A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) [version 1; peer review: 1 approved, 3 approved with reservations] by Christine Orengo, Sameer Velankar, Shoshana Wodak, Vincent Zoete, Alexandre M.J.J. Bonvin, Arne Elofsson, K. Anton Feenstra, Dietland L. Gerloff, Thomas Hamelryck, John M. Hancock, Manuela Helmer-Citterich, Adam Hospital, Modesto Orozco, Anastassis Perrakis, Matthias Rarey, Claudio Soares, Joel L. Sussman, Janet M. Thornton, Pierre Tuffery, Gabor Tusnady, Rikkert Wierenga, Tiina Salminen, Bohdan Schneider

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Erratum to: Making sense of big data in health research: towards an EU action plan by Charles Auffray, Rudi Balling, Inês Barroso, László Bencze, Mikael Benson, Jay Bergeron, Enrique Bernal-Delgado, Niklas Blomberg, Christoph Bock, Ana Conesa, Susanna Del Signore, Christophe Delogne, Peter Devilee, Alberto Di Meglio, Marinus Eijkemans, Paul Flicek, Norbert Graf, Vera Grimm, Henk-Jan Guchelaar, Yi-Ke Guo, Ivo Glynne Gut, Allan Hanbury, Shahid Hanif, Ralf-Dieter Hilgers, Ángel Honrado, D. Rod Hose, Jeanine Houwing-Duistermaat, Tim Hubbard, Sophie Helen Janacek, Haralampos Karanikas, Tim Kievits, Manfred Kohler, Andreas Kremer, Jerry Lanfear, Thomas Lengauer, Edith Maes, Theo Meert, Werner Müller, Dörthe Nickel, Peter Oledzki, Bertrand Pedersen, Milan Petkovic, Konstantinos Pliakos, Magnus Rattray, Josep Redón i Màs, Reinhard Schneider, Thierry Sengstag, Xavier Serra-Picamal, Wouter Spek, Lea A. I. Vaas, Okker van Batenburg, Marc Vandelaer, Peter Varnai, Pablo Villoslada, Juan Antonio Vizcaíno, John Peter Mary Wubbe, Gianluigi Zanetti

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Effects of Subthalamic and Nigral Stimulation on Gait Kinematics in Parkinson’s Disease by Marlieke Scholten, Marlieke Scholten, Marlieke Scholten, Marlieke Scholten, Johannes Klemt, Johannes Klemt, Johannes Klemt, Melanie Heilbronn, Melanie Heilbronn, Melanie Heilbronn, Christian Plewnia, Christian Plewnia, Bastiaan R. Bloem, Friedemann Bunjes, Rejko Krüger, Rejko Krüger, Rejko Krüger, Rejko Krüger, Alireza Gharabaghi, Alireza Gharabaghi, Daniel Weiss, Daniel Weiss, Daniel Weiss

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Genomic and clinical predictors of lacosamide response in refractory epilepsies by Sinéad B. Heavin, Mark McCormack, Stefan Wolking, Lisa Slattery, Nicole Walley, Andreja Avbersek, Jan Novy, Saurabh R. Sinha, Rod Radtke, Colin Doherty, Pauls Auce, John Craig, Michael R. Johnson, Bobby P. C. Koeleman, Roland Krause, Wolfram S. Kunz, Anthony G. Marson, Terence J. O'Brien, Josemir W. Sander, Graeme J. Sills, Hreinn Stefansson, Pasquale Striano, Federico Zara, EPIGEN Consortium, EpiPGX Consortium, Chantal Depondt, Sanjay Sisodiya, David Goldstein, Holger Lerche, Gianpiero L. Cavalleri, Norman Delanty

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Mitochondrial Morphology, Function and Homeostasis Are Impaired by Expression of an N-terminal Calpain Cleavage Fragment of Ataxin-3 by Tina Harmuth, Tina Harmuth, Tina Harmuth, Caroline Prell-Schicker, Jonasz J. Weber, Jonasz J. Weber, Frank Gellerich, Claudia Funke, Stefan Drießen, Janine C. D. Magg, Janine C. D. Magg, Guido Krebiehl, Hartwig Wolburg, Stefanie N. Hayer, Stefanie N. Hayer, Stefan Hauser, Rejko Krüger, Rejko Krüger, Ludger Schöls, Ludger Schöls, Olaf Riess, Olaf Riess, Jeannette Hübener-Schmid, Jeannette Hübener-Schmid

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Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation by Nesli-Ece Sen, Júlia Canet-Pons, Melanie V. Halbach, Aleksandar Arsovic, Ulrich Pilatus, Woon-Hyung Chae, Zeynep-Ece Kaya, Kay Seidel, Ewa Rollmann, Michel Mittelbronn, David Meierhofer, Chris I. De Zeeuw, Laurens W.J. Bosman, Suzana Gispert, Georg Auburger

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Data-Driven Discovery of Stochastic Differential Equations by Yasen Wang, Huazhen Fang, Junyang Jin, Guijun Ma, Xin He, Xing Dai, Zuogong Yue, Cheng Cheng, Hai-Tao Zhang, Donglin Pu, Dongrui Wu, Ye Yuan, Jorge Gonçalves, Jürgen Kurths, Han Ding

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NORMAN guidance on suspect and non-target screening in environmental monitoring by Juliane Hollender, Emma L. Schymanski, Lutz Ahrens, Nikiforos Alygizakis, Frederic Béen, Lubertus Bijlsma, Andrea M. Brunner, Alberto Celma, Aurelie Fildier, Qiuguo Fu, Pablo Gago-Ferrero, Ruben Gil-Solsona, Peter Haglund, Martin Hansen, Sarit Kaserzon, Anneli Kruve, Marja Lamoree, Christelle Margoum, Jeroen Meijer, Sylvain Merel, Cassandra Rauert, Pawel Rostkowski, Saer Samanipour, Bastian Schulze, Tobias Schulze, Randolph R. Singh, Jaroslav Slobodnik, Teresa Steininger-Mairinger, Nikolaos S. Thomaidis, Anne Togola, Katrin Vorkamp, Emmanuelle Vulliet, Linyan Zhu, Martin Krauss

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Relevance of the TRIAP1/p53 axis in colon cancer cell proliferation and adaptation to glutamine deprivation by Kenza Nedara, Camille Reinhardt, Emilie Lebraud, Giuseppe Arena, Giuseppe Arena, Céline Gracia, Valérie Buard, Catherine Pioche-Durieu, Florence Castelli, Benoit Colsch, Paule Bénit, Pierre Rustin, Benoit Albaud, Pierre Gestraud, Sylvain Baulande, Nicolas Servant, Eric Deutsch, Eric Deutsch, Jean-Marc Verbavatz, Catherine Brenner, Fabien Milliat, Nazanine Modjtahedi

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Multifactorial assessment of Parkinson’s disease course and outcomes using trajectory modeling in a multiethnic, multisite cohort – extension of the LONG-PD study by Bruce A. Chase, Rejko Krueger, Rejko Krueger, Rejko Krueger, Rejko Krueger, Lukas Pavelka, Lukas Pavelka, Lukas Pavelka, Sun Ju Chung, Jan Aasly, Jan Aasly, Efthimios Dardiotis, Ashvini P. Premkumar, Bernadette Schoneburg, Ninith Kartha, Navamon Aunaetitrakul, Roberta Frigerio, Demetrius Maraganore, Katerina Markopoulou, Katerina Markopoulou

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Multi-Omics Interdisciplinary Research Integration to Accelerate Dementia Biomarker Development (MIRIADE) by Ekaterina Mavrina, Ekaterina Mavrina, Leighann Kimble, Leighann Kimble, Katharina Waury, Katharina Waury, Dea Gogishvili, Dea Gogishvili, Nerea Gómez de San José, Nerea Gómez de San José, Shreyasee Das, Shreyasee Das, Salomé Coppens, Salomé Coppens, Bárbara Fernandes Gomes, Bárbara Fernandes Gomes, Sára Mravinacová, Sára Mravinacová, Anna Lidia Wojdała, Anna Lidia Wojdała, Katharina Bolsewig, Katharina Bolsewig, Sherif Bayoumy, Sherif Bayoumy, Felicia Burtscher, Felicia Burtscher, Pablo Mohaupt, Pablo Mohaupt, Eline Willemse, Eline Willemse, Charlotte Teunissen, Charlotte Teunissen, the MIRIADE consortium

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Towards a European health research and innovation cloud (HRIC) by F. M. Aarestrup, A. Albeyatti, W. J. Armitage, C. Auffray, L. Augello, R. Balling, N. Benhabiles, G. Bertolini, J. G. Bjaalie, M. Black, N. Blomberg, P. Bogaert, M. Bubak, B. Claerhout, L. Clarke, B. De Meulder, G. D’Errico, A. Di Meglio, N. Forgo, C. Gans-Combe, A. E. Gray, I. Gut, A. Gyllenberg, G. Hemmrich-Stanisak, L. Hjorth, Y. Ioannidis, S. Jarmalaite, A. Kel, F. Kherif, J. O. Korbel, C. Larue, M. Laszlo, A. Maas, L. Magalhaes, I. Manneh-Vangramberen, E. Morley-Fletcher, C. Ohmann, P. Oksvold, N. P. Oxtoby, I. Perseil, V. Pezoulas, O. Riess, H. Riper, J. Roca, P. Rosenstiel, P. Sabatier, F. Sanz, M. Tayeb, G. Thomassen, J. Van Bussel, M. Van den Bulcke, H. Van Oyen

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ImmUniverse Consortium: Multi-omics integrative approach in personalized medicine for immune-mediated inflammatory diseases by Stefania Vetrano, Stefania Vetrano, Gerben Bouma, Robert J. Benschop, Thomas Birngruber, Antonio Costanzo, Antonio Costanzo, G. R. A. M. D’Haens, Loredana Frasca, Rainer Hillenbrand, Lars Iversen, Claus Johansen, Arthur Kaser, Hans J. P. M. Koenen, Christa Noehammer, Laurent Peyrin-Biroulet, Jeroen Raes, Leonardo Ricotti, Leonardo Ricotti, Philip Rosenstiel, Venkata P. Satagopam, Stefan Schreiber, Severine Vermeire, Andreas Wollenberg, Andreas Wollenberg, Stephan Weidinger, Daniel Ziemek, Silvio Danese, Silvio Danese, Silvio Danese, ImmUniverse Consortium, Alessandro Armuzzi, Alessia Butera, Andrea Cafarelli, Lucia Ciglar, Ellen van den Bogaard, Elke MGJ de Jong, Ernst Dow, Marjolijn Duijvenstein, Ahmed Essaghir, Rebecca Favaro, Gionata Fiorino, Soumyabrata Ghosh, Wei Gu, Robert Häsler, Xuehui He, Roberto Lande, Judith Logmans, Christoph Magnes, Karl Nocka, Loulou Peisl, Samuel Pineda Chavez, Angela Sorriento, Klemens Vierlinger, Laurien Waaijer, Xinhui Wang, Nicolas Wisniacki, Mary Zuniga

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Severe metabolic alterations in liver cancer lead to ERK pathway activation and drug resistance by Zeribe Chike Nwosu, Weronika Piorońska, Nadia Battello, Andreas David Zimmer, Bedair Dewidar, Mei Han, Sharon Pereira, Biljana Blagojevic, Darko Castven, Verodia Charlestin, Pavlo Holenya, Julia Lochead, Carolina De La Torre, Norbert Gretz, Peter Sajjakulnukit, Li Zhang, Matthew H. Ward, Jens U. Marquardt, Marina Pasca di Magliano, Costas A. Lyssiotis, Jonathan Sleeman, Stefan Wölfl, Matthias Philip Ebert, Christoph Meyer, Ute Hofmann, Steven Dooley

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Enhancement of COPD biological networks using a web-based collaboration interface [v2; ref status: indexed, http://f1000r.es/5ew] by The sbv IMPROVER project team (in alphabetical order), Stephanie Boue, Brett Fields, Julia Hoeng, Jennifer Park, Manuel C. Peitsch, Walter K. Schlage, Marja Talikka, The Challenge Best Performers (in alphabetical order), Ilona Binenbaum, Vladimir Bondarenko, Oleg V. Bulgakov, Vera Cherkasova, Norberto Diaz-Diaz, Larisa Fedorova, Svetlana Guryanova, Julia Guzova, Galina Igorevna Koroleva, Elena Kozhemyakina, Rahul Kumar, Noa Lavid, Qingxian Lu, Swapna Menon, Yael Ouliel, Samantha C. Peterson, Alexander Prokhorov, Edward Sanders, Sarah Schrier, Golan Schwaitzer Neta, Irina Shvydchenko, Aravind Tallam, Gema Villa-Fombuena, John Wu, Ilya Yudkevich, Mariya Zelikman

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Serine metabolism is crucial for cGAS-STING signaling and viral defense control in the gut by Björn Becker, Felix Wottawa, Mohamed Bakr, Eric Koncina, Lisa Mayr, Julia Kugler, Guang Yang, Samuel J. Windross, Laura Neises, Neha Mishra, Danielle Harris, Florian Tran, Lina Welz, Julian Schwärzler, Zoltán Bánki, Stephanie T. Stengel, Go Ito, Christina Krötz, Olivia I. Coleman, Christian Jaeger, Dirk Haller, Søren R. Paludan, Richard Blumberg, Arthur Kaser, Luka Cicin-Sain, Stefan Schreiber, Timon E. Adolph, Elisabeth Letellier, Philip Rosenstiel, Johannes Meiser, Konrad Aden

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Model-based assessment of mammalian cell metabolic functionalities using omics data by Anne Richelle, Benjamin P. Kellman, Alexander T. Wenzel, Austin W.T. Chiang, Tyler Reagan, Jahir M. Gutierrez, Chintan Joshi, Shangzhong Li, Joanne K. Liu, Helen Masson, Jooyong Lee, Zerong Li, Laurent Heirendt, Christophe Trefois, Edwin F. Juarez, Tyler Bath, David Borland, Jill P. Mesirov, Kimberly Robasky, Nathan E. Lewis

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An ecotoxicological view on neurotoxicity assessment by J. B. Legradi, C. Di Paolo, M. H. S. Kraak, H. G. van der Geest, E. L. Schymanski, A. J. Williams, M. M. L. Dingemans, R. Massei, W. Brack, X. Cousin, M.-L. Begout, R. van der Oost, A. Carion, V. Suarez-Ulloa, F. Silvestre, B. I. Escher, M. Engwall, G. Nilén, S. H. Keiter, D. Pollet, P. Waldmann, C. Kienle, I. Werner, A.-C. Haigis, D. Knapen, L. Vergauwen, M. Spehr, W. Schulz, W. Busch, D. Leuthold, S. Scholz, C. M. vom Berg, N. Basu, C. A. Murphy, A. Lampert, J. Kuckelkorn, T. Grummt, H. Hollert

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Systems Biology in ELIXIR: modelling in the spotlight [version 1; peer review: 1 approved, 2 approved with reservations] by Katharina F. Heil, Anze Zupanic, Chris T. Evelo, Carole Goble, Kristel Van Steen, Tadeja Rezen, Hans V Westerhoff, Rahuman S. Malik Sheriff, Maria Suarez Diez, Henning Hermjakob, Marco Pagni, Damjana Rozman, Barbara Szomolay, Miguel Rocha, Jasper Koehorst, Alexey Kolodkin, Victoria Dominguez Del Angel, David Šafránek, Dirk Fey, Ilja Arts, Rui Benfeitas, Vitor Martins dos Santos, Mihail Anton, Marek Ostaszewski, Ulrike Wittig, John M. Hancock, Brane Leskošek, Katherine Wolstencroft, Martin Golebiewski, Wolfgang Müller, Polonca Ferk, Kristina Gruden, Martina Kutmon, Maria I. Klapa, Sébastien Moretti, Pascal Kahlem

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Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions by Isabel Moreno-Indias, Isabel Moreno-Indias, Leo Lahti, Miroslava Nedyalkova, Ilze Elbere, Gennady Roshchupkin, Muhamed Adilovic, Onder Aydemir, Burcu Bakir-Gungor, Enrique Carrillo-de Santa Pau, Domenica D’Elia, Mahesh S. Desai, Mahesh S. Desai, Laurent Falquet, Laurent Falquet, Aycan Gundogdu, Aycan Gundogdu, Karel Hron, Thomas Klammsteiner, Marta B. Lopes, Marta B. Lopes, Laura Judith Marcos-Zambrano, Cláudia Marques, Michael Mason, Patrick May, Lejla Pašić, Gianvito Pio, Sándor Pongor, Vasilis J. Promponas, Piotr Przymus, Julio Saez-Rodriguez, Alexia Sampri, Rajesh Shigdel, Blaz Stres, Blaz Stres, Blaz Stres, Ramona Suharoschi, Jaak Truu, Ciprian-Octavian Truică, Baiba Vilne, Dimitrios Vlachakis, Ercument Yilmaz, Georg Zeller, Aldert L. Zomer, David Gómez-Cabrero, Marcus J. Claesson

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