Comparison of two protocols for the generation of iPSC-derived human astrocytes by Patrycja Mulica, Carmen Venegas, Zied Landoulsi, Katja Badanjak, Sylvie Delcambre, Maria Tziortziou, Soraya Hezzaz, Jenny Ghelfi, Semra Smajic, Jens Schwamborn, Rejko Krüger, Paul Antony, Patrick May, Enrico Glaab, Anne Grünewald, Sandro L. Pereira

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A microfluidics-based in vitro model of the gastrointestinal human–microbe interface by Pranjul Shah, Joëlle V. Fritz, Enrico Glaab, Mahesh S. Desai, Kacy Greenhalgh, Audrey Frachet, Magdalena Niegowska, Matthew Estes, Christian Jäger, Carole Seguin-Devaux, Frederic Zenhausern, Paul Wilmes

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Birth mode is associated with earliest strain-conferred gut microbiome functions and immunostimulatory potential by Linda Wampach, Anna Heintz-Buschart, Joëlle V. Fritz, Javier Ramiro-Garcia, Janine Habier, Malte Herold, Shaman Narayanasamy, Anne Kaysen, Angela H. Hogan, Lutz Bindl, Jean Bottu, Rashi Halder, Conny Sjöqvist, Patrick May, Anders F. Andersson, Carine de Beaufort, Paul Wilmes

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Publisher Correction: Age at onset as stratifier in idiopathic Parkinson’s disease – effect of ageing and polygenic risk score on clinical phenotypes by L. Pavelka, A. Rauschenberger, Z. Landoulsi, S. Pachchek, P. May, E. Glaab, R. Krüger, on behalf of the NCER-PD Consortium

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Altered infective competence of the human gut microbiome in COVID-19 by Laura de Nies, Valentina Galata, Camille Martin-Gallausiaux, Milena Despotovic, Susheel Bhanu Busi, Chantal J. Snoeck, Lea Delacour, Deepthi Poornima Budagavi, Cédric Christian Laczny, Janine Habier, Paula-Cristina Lupu, Rashi Halder, Joëlle V. Fritz, Taina Marques, Estelle Sandt, Marc Paul O’Sullivan, Soumyabrata Ghosh, Venkata Satagopam, CON-VINCE Consortium, Rejko Krüger, Guy Fagherazzi, Markus Ollert, Feng Q. Hefeng, Patrick May, Paul Wilmes

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The Translational Data Catalog - discoverable biomedical datasets by Danielle Welter, Philippe Rocca-Serra, Valentin Grouès, Nirmeen Sallam, François Ancien, Abetare Shabani, Saeideh Asariardakani, Pinar Alper, Soumyabrata Ghosh, Tony Burdett, Susanna-Assunta Sansone, Wei Gu, Venkata Satagopam

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Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells by Anna S. Monzel, Lisa M. Smits, Kathrin Hemmer, Siham Hachi, Edinson Lucumi Moreno, Thea van Wuellen, Javier Jarazo, Jonas Walter, Inga Brüggemann, Ibrahim Boussaad, Emanuel Berger, Ronan M.T. Fleming, Silvia Bolognin, Jens C. Schwamborn

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The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1 by Jonas Walter, Silvia Bolognin, Suresh K. Poovathingal, Stefano Magni, Deborah Gérard, Paul M.A. Antony, Sarah L. Nickels, Luis Salamanca, Emanuel Berger, Lisa M. Smits, Kamil Grzyb, Rita Perfeito, Fredrik Hoel, Xiaobing Qing, Jochen Ohnmacht, Michele Bertacchi, Javier Jarazo, Tomasz Ignac, Anna S. Monzel, Laura Gonzalez-Cano, Rejko Krüger, Thomas Sauter, Michèle Studer, Luis Pereira de Almeida, Karl J. Tronstad, Lasse Sinkkonen, Alexander Skupin, Jens C. Schwamborn

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Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids by Isabel Rosety, Alise Zagare, Claudia Saraiva, Sarah Nickels, Paul Antony, Catarina Almeida, Enrico Glaab, Rashi Halder, Sergiy Velychko, Thomas Rauen, Hans R. Schöler, Silvia Bolognin, Thomas Sauter, Javier Jarazo, Rejko Krüger, Jens C. Schwamborn

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Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality by Jonas Walter, Silvia Bolognin, Paul M.A. Antony, Sarah L. Nickels, Suresh K. Poovathingal, Luis Salamanca, Stefano Magni, Rita Perfeito, Fredrik Hoel, Xiaobing Qing, Javier Jarazo, Jonathan Arias-Fuenzalida, Tomasz Ignac, Anna S. Monzel, Laura Gonzalez-Cano, Luis Pereira de Almeida, Alexander Skupin, Karl J. Tronstad, Jens C. Schwamborn

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Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function by Peter A. Barbuti, Jochen Ohnmacht, Bruno F. R. Santos, Paul M. Antony, François Massart, Gérald Cruciani, Claire M. Dording, Lukas Pavelka, Nicolas Casadei, Yong-Jun Kwon, Rejko Krüger

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Generation of isogenic control DJ-1-delP GC13 for the genetic Parkinson‘s disease-patient derived iPSC line DJ-1-delP (LCSBi008-A-1) by Pauline Mencke, Zoé Hanss, Javier Jarazo, François Massart, Arkadiusz Rybicki, Elizabet Petkovski, Enrico Glaab, Ibrahim Boussaad, Vincenzo Bonifati, Jens Christian Schwamborn, Wim Mandemakers, Rejko Krüger

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Occurrence and Distribution of Pharmaceuticals and Their Transformation Products in Luxembourgish Surface Waters by Randolph R. Singh, Adelene Lai, Jessy Krier, Todor Kondić, Philippe Diderich, Emma L. Schymanski

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Author Correction: SeesawPred: a web application for predicting cell-fate determinants in cell differentiation by András Hartmann, Satoshi Okawa, Gaia Zaffaroni, Antonio del Sol

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Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.815G > A (p.R2... by Axel Chemla, Giuseppe Arena, Gizem Onal, Jonas Walter, Clara Berenguer-Escuder, Dajana Grossmann, Anne Grünewald, Jens C. Schwamborn, Rejko Krüger

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Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by integrated multi-omic analyses by B. J. Kunath, O. Hickl, P. Queirós, C. Martin-Gallausiaux, L. A. Lebrun, R. Halder, C. C. Laczny, T. S. B. Schmidt, M. R. Hayward, D. Becher, A. Heintz-Buschart, C. de Beaufort, P. Bork, P. May, P. Wilmes

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Gut microbiome is not associated with mild cognitive impairment in Parkinson’s disease by Velma T. E. Aho, Matthias Klee, Zied Landoulsi, Anna Heintz-Buschart, Lukas Pavelka, Anja K. Leist, Rejko Krüger, Patrick May, Paul Wilmes, on behalf of the NCER-PD Consortium

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Small RNA profiling of low biomass samples: identification and removal of contaminants by Anna Heintz-Buschart, Dilmurat Yusuf, Anne Kaysen, Alton Etheridge, Joëlle V. Fritz, Patrick May, Carine de Beaufort, Bimal B. Upadhyaya, Anubrata Ghosal, David J. Galas, Paul Wilmes

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Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-dependent dysregulations by Muhammad Ali, Pierre Garcia, Laetitia P. Lunkes, Alessia Sciortino, Melanie Thomas, Tony Heurtaux, Kamil Grzyb, Rashi Halder, Djalil Coowar, Alex Skupin, Luc Buée, David Blum, Manuel Buttini, Enrico Glaab

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Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease by Kristopher J. Schmit, Pierre Garcia, Alessia Sciortino, Velma T.E. Aho, Beatriz Pardo Rodriguez, Mélanie H. Thomas, Jean-Jacques Gérardy, Irati Bastero Acha, Rashi Halder, Camille Cialini, Tony Heurtaux, Irina Ostahi, Susheel B. Busi, Léa Grandmougin, Tuesday Lowndes, Yogesh Singh, Eric C. Martens, Michel Mittelbronn, Manuel Buttini, Paul Wilmes

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