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Construction of recombinant newcastle disease virus expressing granulocyte-macrophage colony-stimulating factor
Published 2022“…The expression of both GM-CSF genes was determined via ELISA. High hGM-CSF and mGM-CSF glycoproteins were expressed by both rAF-GFP/hGM-CSF and rAF-GFP/mGM-CSF virus during viral infection in human colorectal carcinoma cells. …”
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2
Immune enhancement of nitroreductase-induced cytotoxicity: studies using a bicistronic adenovirus vector.
Published 2003“…We have preliminary data suggesting an immune bystander effect with NR to further examine these effects and their potential enhancement by cytokines, an adenoviral vector containing CMV-NR, an internal ribosome entry site (IRES) and the gene for murine GM-CSF (mGM-CSF) was constructed. The NR-GM-CSF virus was validated in 2 experimental models and demonstrated increased therapeutic efficacy in the MC26 murine colorectal tumour model. …”
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3
The Psyche Gravity Investigation
Published 2022“…Orbital gravity will allow an estimate of G M $GM$ to better than 0.001 km3 s−2. …”
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Generalized M-estimation for the accelerated failure time model
Published 2017“…In this paper, we propose a robust weighted generalized M (GM) estimation for the AFT model with right-censored data by appropriately using the Kaplan–Meier weights in the GM–type objective function to estimate the regression coefficients and scale parameter simultaneously. …”
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Journal Article -
5
In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease
Published 2023“…One resultant potent Mpro inhibitor (IC50 = 50 nM), GM4, comprising 13 residues with γ1 at the 4th position, manifests a 5.2 nM dissociation constant. …”
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6
Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression
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