Matrin3 (MATR3) Expression Is Associated with Hemophagocytosis by Wen-Chi Yang, Sheng-Fung Lin, Shih-Chi Wu, Chih-Wen Shu

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MATR3 is an endogenous inhibitor of DUX4 in FSHD muscular dystrophy by Valeria Runfola, Roberto Giambruno, Claudia Caronni, Maria Pannese, Annapaola Andolfo, Davide Gabellini

“…Collectively, our data suggest MATR3 as a candidate for developing a treatment for FSHD.…”
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Selective Loss of MATR3 in Spinal Interneurons, Upper Motor Neurons and Hippocampal CA1 Neurons in a MATR3 S85C Knock-In Mouse Model of Amyotrophic Lateral Sclerosis by Justin You, Katarina Maksimovic, Jooyun Lee, Mashiat Khan, Rintaro Masuda, Jeehye Park

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Low Expression of MATR3 Is Associated with Poor Survival in Clear Cell Renal Cell Carcinoma by Justyna Durślewicz, Anna Klimaszewska-Wiśniewska, Paulina Antosik, Dariusz Grzanka

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Long non-coding RNA MIDEAS-AS1 inhibits growth and metastasis of triple-negative breast cancer via transcriptionally activating NCALD by Dan Luo, Yiran Liang, Yajie Wang, Fangzhou Ye, Yuhan Jin, Yaming Li, Dianwen Han, Zekun Wang, Bing Chen, Wenjing Zhao, Lijuan Wang, Xi Chen, Liyu Jiang, Qifeng Yang

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The Impact of ALS-Associated Genes <i>hnRNPA1</i>, <i>MATR3</i>, <i>VCP</i> and <i>UBQLN2</i> on the Severity of TDP-43 Aggregation by Ana Bajc Česnik, Helena Motaln, Boris Rogelj

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Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function by Myers Michael P, Kleva Danijela, Knezevich Anna, Guerra Jessica, Kula Anna, Marcello Alessandro

“…Knockdown of MATR3 suppressed Rev/RRE function in the export of unspliced HIV-1 RNAs. …”
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Matrin3 mediates differentiation through stabilizing chromatin loop-domain interactions and YY1 mediated enhancer-promoter interactions by Tianxin Liu, Qian Zhu, Yan Kai, Trevor Bingham, Stacy Wang, Hye Ji Cha, Stuti Mehta, Thorsten M. Schlaeger, Guo-Cheng Yuan, Stuart H. Orkin

“…Changes in chromatin occupancy by Matr3 also correlated with these alterations. Overall, our results suggest that Matr3 mediates differentiation through stabilizing chromatin accessibility and chromatin loop-domain interactions, and highlight a conserved and direct role for Matr3 in maintenance of chromosomal architecture.…”
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Research on radiotherapy related genes and prognostic target identification of rectal cancer based on multi-omics by Yi Liu, Yanguang Yang, Feng Ni, Guomei Tai, Cenming Yu, Xiaohui Jiang, Ding Wang

“…Five key genes, TOP2A, MATR3, APOL6, JOSD1, and HOXC6, were finally screened by random survival forest analysis. …”
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Integrative identification of hub genes in development of atrial fibrillation related stroke by Kai Huang, Xi Fan, Yuwen Jiang, Sheng Jin, Jiechun Huang, Liewen Pang, Yiqing Wang, Yuming Wu, Xiaotian Sun

“…Co-expressed hub genes of EIF4E3, ZNF595, ZNF700, MATR3, ACKR4, ANXA3, SEPSECS-AS1, and RNF166 were significantly associated with AF-related stroke. …”
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Integrative identification of hub genes in development of atrial fibrillation related stroke. by Kai Huang, Xi Fan, Yuwen Jiang, Sheng Jin, Jiechun Huang, Liewen Pang, Yiqing Wang, Yuming Wu, Xiaotian Sun

“…Co-expressed hub genes of EIF4E3, ZNF595, ZNF700, MATR3, ACKR4, ANXA3, SEPSECS-AS1, and RNF166 were significantly associated with AF-related stroke. …”
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CIZ1 in Xist seeded assemblies at the inactive X chromosome by Sajad Sofi, Dawn Coverley, Dawn Coverley

“…However, among the many proteins recruited to the inactive X chromosome by Xist long non-coding RNA, so far only a minority (CIZ1, CELF1, SPEN, TDP-43, MATR3, PTBP1, PCGF5) have been shown to form Xist-seeded protein assemblies, and of these most have not been analyzed in detail. …”
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Expression of Long Noncoding RNAs in Fibroblasts from Mucopolysaccharidosis Patients by Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, Grzegorz Węgrzyn

“…Some potential target genes for these lncRNAs were identified, and correlations between changed levels of specific lncRNAs and modulations in the abundance of mRNA transcripts of these genes (<i>HNRNPC, FXR1</i>, <i>TP53</i>, <i>TARDBP</i>, and <i>MATR3</i>) were found. Interestingly, the affected genes code for proteins involved in various regulatory processes, especially gene expression control through interactions with DNA or RNA regions. …”
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Nationwide survey of patients with multisystem proteinopathy in Japan by Satoshi Yamashita, Yuji Takahashi, Jun Hashimoto, Ayuka Murakami, Ryoichi Nakamura, Masahisa Katsuno, Rumiko Izumi, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, the Japan MSP Study Group

“…Mutations in VCP, HNRNPA2B1, HNRNPA1, SQSTM1, MATR3, and ANXA11 are causative for MSP. This study aimed to conduct a nationwide epidemiological survey based on the diagnostic criteria established by the Japan MSP study group. …”
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Multisystem proteinopathies (MSPs) and MSP‐like disorders: Clinical‐pathological‐molecular spectrum by Pitcha Chompoopong, Björn Oskarsson, Nicolas N. Madigan, Igal Mirman, Jennifer M. Martinez‐Thompson, Teerin Liewluck, Margherita Milone

“…Results Thirty‐one individuals (27 families) had pathogenic mutations in: VCP (n = 17), SQSTM1 + TIA1 (n = 5), TIA1 (n = 5), MATR3, HNRNPA1, HSPB8, and TFG (n = 1, each). Myopathy occurred in all but 2 VCP‐MSP patients with disease onset at age 52 (median). …”
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Identification of mitophagy-related biomarkers and immune infiltration in major depressive disorder by Jing Zhang, Shujun Xie, Rong Xiao, Dongrong Yang, Zhi Zhan, Yan Li

“…Two distinct clusters with diverse immune infiltration characteristics were identified in the 144 MDD samples. MATR3, ACTL6A, FUS, BIRC2, and RIPK1 have been identified as potential biomarkers of MDD. …”
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TRPC4 deletion elicits behavioral defects in sociability by dysregulating expression of microRNA-138-2 by Jee Young Seo, Hye-Ryeong Jo, Seung Hoon Lee, Do Gyeong Kim, Huiju Lee, Ye Lim Kim, Young In Choi, Sung Jun Jung, Hyeon Son

“…We also found that binding of Matrin3 (MATR3), a selective miR-138-2 binding nuclear protein, to miR-138-2 was prominently enhanced, resulting in the downregulation of miR-138 in Trpc4−/− mice. …”
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The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart by Valeria Taliani, Giulia Buonaiuto, Fabio Desideri, Adriano Setti, Tiziana Santini, Silvia Galfrè, Leonardo Schirone, Davide Mariani, Giacomo Frati, Valentina Valenti, Sebastiano Sciarretta, Emerald Perlas, Carmine Nicoletti, Antonio Musarò, Monica Ballarino

“…Since the early steps of cardiomyogenesis, we found the lncRNA being specifically restricted to cardiomyocytes, where it assists the formation of specific nuclear condensates containing MATR3, as well as important RNAs for cardiac development. …”
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Exosomal miR-200c and miR-141 as cerebrospinal fluid biopsy biomarkers for the response to chemotherapy in primary central nervous system lymphoma by Yao Hu, Qingyun Zhang, Zhiyuan Wu, Kun Chen, Xiao Xu, Weizhe Ma, Bobin Chen, Limin Jin, Ming Guan

“…The potential target genes of miR-200c and miR-141 in PCNSL included ATP1B3, DYNC1H1, MATR3, NUCKS1, ZNF638, NUDT4, RCN2, GNPDA1, ZBTB38, and DOLK. …”
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Artistic representations of data can help bridge the US political divide over climate change by Nan Li, Isabel I. Villanueva, Thomas Jilk, Brianna Rae Van Matre, Dominique Brossard

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