Comparison of Remimazolam–Flumazenil versus Propofol for Recovery from General Anesthesia: A Systematic Review and Meta-Analysis by Quantong Wu, Fuchao Xu, Jie Wang, Ming Jiang

“…Compared to propofol, the remimazolam–flumazenil combination shortened the emergence time (MD = −4.34 min, 95% CI = [−6.88, −1.81], <i>p</i> = 0.0008, low certainty), extubation time (MD = −4.26 min, 95% CI = [−6.81, −1.7], <i>p</i> = 0.0011, low certainty), and the post-anesthesia care unit (PACU) stay (MD = −4.42 min, 95% CI = [−7.45, −1.38], <i>p</i> = 0.0044, low certainty), while reducing the incidence of respiratory depression (RR = 0.2, 95% CI = [0.04, 0.89], <i>p</i> = 0.03, high certainty) after general anesthesia. …”
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Effects and safety of Ginkgo biloba on depression: a systematic review and meta-analysis by Jingya Lin, Xiaojing Sun, Lingli Yang

“…Several outcomes showed a difference, and the GKB group had better results than the control group, including the Hamilton Depression Scale (HAMD), after taking GKB for 4 weeks (MD = −2.86, 95%CI [−4.27, −1.46], p &lt; 0.01), 6 weeks (mean difference (MD) = −3.36, 95%CI [−4.05, −2.67], p &lt; 0.01), and 8 weeks (MD = −4.58, 95% CI [−6.11, −3.05], p &lt; 0.01), modified Barthel index (MBI) (MD = 14.86, 95%CI [12.07, 17.64], p &lt; 0.01), modified Edinburgh-Scandinavian stroke scale (MESSS) (MD = −4.57, 95%CI [−6.34, −2.79], p &lt; 0.01), brain-derived neurotrophic factor (BDNF) (MD = 16.35, 95%CI [7.34, 25.36], p &lt; 0.01), 5-hydroxytryptamine (5-HT) (MD = 4.57, 95%CI [3.08, 6.05], p &lt; 0.01), and clinical efficacy (risk ratio, RR = 1.24, 95%CI [1.17, 1.32], p &lt; 0.01). …”
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Xinmailong injection on left ventricular remodeling and inflammatory mediators in patients with CHF: a systematic review and meta-analysis by Xu Han, Xi Chen, Yanling Liu, Jie Yang, Wuzhi Nie, Mingjiu Yang, Xinglang Mou

“…Furthermore, statistical analysis, sensitivity analysis, and publication bias assessment were conducted using Stata 17.0 software.Result:Compared with conventional treatment (CT), the combination therapy of XMLI and CT significantly improved LVR and reduced inflammatory mediators, mainly manifested by an increase in LVEF (MD = 6.40, 95% CI: 5.25 to 7.55, p = 0.000), a decrease in LVEDD (MD = −4.63, 95% CI: −5.69 to −3.57, p = 0.000) and LVESD (MD = −4.00, 95% CI: −5.50 to −2.50, p = 0.000), as well as a decrease in TNF-α (MD = −7.93, 95% CI: −9.86 to −6.00, p = 0.000), IL-6 (MD = −5.25, 95% CI: −6.59 to −3.92, p = 0.000), IL-18 (MD = −36.07, 95% CI: −46.76 to −25.38, p = 0.000), CRP (MD = −4.41, 95% CI: −6.40 to −2.42, p = 0.000), hs-CRP (MD = −4.90, 95% CI: −5.71 to −4.08, p = 0.000), and an increase in IL-10 (MD = 20.19, 95% CI: 10.42 to 29.97, p = 0.000). …”
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Comparison of the external load of professional goalkeepers in different weekly training sessions by David Casamichana, Eider Barba, Andres Martín-García, Iñaki Ulloa, Fabio Yuzo Nakamura, Julen Castellano

“…Three professional GKs (age: 28.1±6.9 years; stature: 190.1±1.9 cm; body mass: 84.8±1.1 kg) were monitored by GPS devices during different training sessions according to the days since/until the match day (MD) at MD+1, MD-4, MD-3, MD-2 and MD-1. Different external load measures were calculated: total distance, distance covered at > 14 km· h −1 , acceleration load, player load, number of dives, dive load, number of explosive efforts of displacement, number of low intensity ( 0.4 m) and medium-high intensity jumps (> 0.3 m). …”
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Signals from a self-antigen induce positive selection in early B cell ontogeny but are tolerogenic in adults. by Ferry, H, Crockford, T, Leung, J, Cornall, R

“…To address this question, we have studied the development of anti-hen egg lysozyme MD4 Ig transgene B cells while systematically varying the level, distribution, and timing of exposure to different forms of hen egg lysozyme as a self-Ag. …”

Crowdsourcing for Plagiocephaly Helmets – A National Review by Brendan Podszus, Jason Pham, Erika Dopson, Shikha Trivedi, Yifan Guo, MD

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Meta-analysis of the efficacy of intravitreal Ranibizumab combined with compound trabeculectomy and panretinal photocoagulation in the treatment of neovascular glaucoma by Xiao-Lan Zhao, Hong-Yu Zhu, Yan-Ni Dai, Xiao-Li Yang

“…Meta-analysis showed that the intraocular pressure of patients in the experimental group was lower than that in the control group at 1wk, 1 and 3mo after surgery(1wk: MD=-4.00, 95%CI: -4.62～-3.38, P&#x003C;0.05; 1mo: MD=-4.11, 95%CI: -4.66～-3.56, P&#x003C;0.05; 3mo: MD=-4.58, 95%CI: -5.61～-3.55, P&#x003C;0.05). …”
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The Quality of Life of Patients Living with a Urinary Catheter and Its Associated Factors: A Cross-Sectional Study in Egypt by Naglaa Youssef, Ashley Shepherd, Catherine Best, Suzanne Hagen, William Mackay, Debbie Waddell, Hanan El Sebaee

“…Moreover, catheter material was significantly related to the catheter function domain with Silicone Foley Catheter (100% Silicon) users experiencing poorer QoL related to catheter function than those with Latex Foley Catheter (Silicon-coated) (MD 4.43 (95% CI: 0.62 to 8.24). Workers/employees were found to have poorer QoL than those who were retired (MD = 4.94 (95% CI: 0.3 to 9.63)). …”
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Esophageal stent placement without optical or fluoroscopic visualization by Michael M. Mwachiro, MBChB, Robert K. Parker, MD, Robert Chepkwony, KRCHN, Stephen L. Burgert, MD, Russell E. White, MD

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Macromastia and Reduction Mammoplasty: Analysis of Total Cost of Care and Opioid Consumption at 10 Years Postoperatively by Kayvon Jabbari, MPH, Michael B Gehring, MD, Matthew L Iorio, MD, David W Mathes, MD, Christodoulos Kaoutzanis, MD

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Endoscopic submucosal dissection of a large pedunculated gastric polyp causing gastric outlet obstruction using clip-snare traction technique by Shelini Sooklal, MD, Siva Raja, MD, Sunguk Jang, MD, Scott Robertson, MD, PhD, Amit Bhatt, MD

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Barriers to Obtaining Orthodontic Care for Patients with Orofacial Clefts: A Survey of Orthodontists and Families by Molly Macisaac, Joshua Wright, Lindsay Schuster, Jordan Halsey, MD, S. Alex Rottgers, MD

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DIEP Flap Salvage of Infected Tissue Expanders by William Tian, Amanda Sergesketter, MD, Ronnie Shammas, MD, Annie Glenney, Scott Hollenbeck, MD

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Knife-assisted resection of flat dysplastic lesions in colitis by Kesavan Kandiah, MBChB, Sharmila Subramaniam, MBChB, Fergus Chedgy, MBBS, Sreedhari Thayalasekaran, MBBS, Pradeep Bhandari, MBBS, MD

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Analysis of Costs Associated with Revascularization and Replantation of Digits by Sagar S Deshpande, MD, Sergey Toshinskiy, MD, Michelle Frees, MD, Pedram Zargari, MD, Chrisopher Hillard, MD

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Endoscopic findings of esophageal submucosal gland duct adenoma by Juan Reyes Genere, MD, Hee Eun Lee, MD, PhD, Tsung-Teh Wu, MD, David O. Prichard, MB, BCh, PhD, Kenneth K. Wang, MD

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Endoscopic salvage of a large esophagojejunostomy dehiscence by Omar Y. Mousa, MD, Bhaumik Brahmbhatt, MD, Monia Werlang, MD, Maoyin Pang, MD, Timothy A. Woodward, MD

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Review of Outpatient Aesthetic Surgery Complications by Dieter Brummund, MD, Brittany Puebla, MBS, Samuel Ruiz, Haaris Mir, MD, Orlando Morejon, MD

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Free Fibula Mandible Reconstruction for Osteoradionecrosis is More Challenging than for Primary Cancer by Z-Hye Lee, MD, John Shuck, MD, Rene Largo, MD, Edward Chang, MD, Matthew Hanasono, MD, Peirong Yu, MD, Patrick Garvey, MD, FACS

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Magnetic anchor-guided endoscopic submucosal dissection for colonic tumor by Ippei Matsuzaki, MD, PhD, Sho Isobe, MD, Ken Hirose, MD, Takahiro Marukawa, MD, Masaya Esaki, MD

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