Structural Basis of Sequential and Concerted Cooperativity by Veronica Morea, Francesco Angelucci, Jeremy R. H. Tame, Enrico Di Cera, Andrea Bellelli

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Bohr equation and the lost allosteric Bohr effects in symmetry by Lihsin Lee

Subjects: “…monod-wyman-changeux (mwc) model…”
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A modular gradient‐sensing network for chemotaxis in Escherichia coli revealed by responses to time‐varying stimuli by Thomas S Shimizu, Yuhai Tu, Howard C Berg

Subjects: “…Monod‐Wyman‐Changeux (MWC) model…”
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Quantitative dissection of transcription in development yields evidence for transcription-factor-driven chromatin accessibility by Elizabeth Eck, Jonathan Liu, Maryam Kazemzadeh-Atoufi, Sydney Ghoreishi, Shelby A Blythe, Hernan G Garcia

“…Here, we systematically tested the predictive power of models of DNA accessibility based on the Monod-Wyman-Changeux (MWC) model of allostery, which posits that chromatin fluctuates between accessible and inaccessible states. …”
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Effect of magnitude and variability of energy of activation in multisite ultrasensitive biochemical processes. by Leonila Lagunes, Lee Bardwell, German A Enciso

“…We use a generalized Monod-Wyman-Changeux (MWC) model that allows for variable conformational free energy contributions from distinct sites, and associate a so-called activation parameter to each site. …”
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Physiological Role of Glutamate Dehydrogenase in Cancer Cells by Rafael Moreno-Sánchez, Álvaro Marín-Hernández, Juan C. Gallardo-Pérez, Silvia C. Pacheco-Velázquez, Diana X. Robledo-Cadena, Joaquín Alberto Padilla-Flores, Emma Saavedra, Sara Rodríguez-Enríquez

“…In contrast, data fitting to the Monod–Wyman–Changeux (MWC) model revealed lower Km values for NH4+, of 6 to 12 mM. …”
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A general framework for thermodynamically consistent parameterization and efficient sampling of enzymatic reactions. by Pedro Saa, Lars K Nielsen

“…The former integrates the generalized MWC model and the elementary reaction formalism. By formulating the appropriate thermodynamic constraints, our framework enables parameterization of any oligomeric enzyme kinetics without sacrificing complexity or using simplifying assumptions. …”
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A Modulated Wideband Converter Model Based on Linear Algebra and Its Application to Fast Calibration by Gilles Burel, Anthony Fiche, Roland Gautier

“…In this paper, we develop an MWC model that is entirely based on linear algebra, matrix theory and block processing. …”
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The tertiary origin of the allosteric activation of E. coli glucosamine-6-phosphate deaminase studied by sol-gel nanoencapsulation of its T conformer. by Sergio Zonszein, Laura I Álvarez-Añorve, Roberto J Vázquez-Núñez, Mario L Calcagno

“…By fitting the velocity-substrate curves as a linear combination of two hyperbolic functions with Kt and Kr as KM values, we obtained comparable values to those reported for the quaternary conformers in solution fitted to MWC model. These results are discussed in the background of the known crystallographic structures of T and R EcGNPDA conformers. …”
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Vibration Response of Manual Wheelchairs According to Loads, Propulsion Methods, Speeds, and Ground Floor Types by Ophélie Larivière, Delphine Chadefaux, Christophe Sauret, Patricia Thoreux

“…A possible solution relies on the implementation of a User/MWC model to point out the effect of propelling conditions (MWC loads, propulsion methods, speeds, and ground floor types) on the vibration exposure and eventually on the MWC user’s health. …”
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Structures of oxygen dissociation intermediates of 400 kDa V2 hemoglobin provide coarse snapshots of the protein allostery by Nobutaka Numoto, Seiko Onoda, Yoshiaki Kawano, Hideo Okumura, Seiki Baba, Yoshihiro Fukumori, Kunio Miki, Nobutoshi Ito

“…Our crystallographic snapshots of the allosteric transition of V2Hb provide important experimental evidence for a more detailed understanding of the allostery of Hbs by extension of the Monod–Wyman–Changeux (MWC) model.…”
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Allosteric mechanism of the V. vulnificus adenine riboswitch resolved by four-dimensional chemical mapping by Siqi Tian, Wipapat Kladwang, Rhiju Das

“…These LM2R measurements give strong support to the pre-existing correlations predicted by MWC models, disfavor alternative models, and suggest additional structural heterogeneities that may be general across ligand-free riboswitches.…”
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Regulation of KATP channel activity by Usher, S

“…The combination of binding and current measurements with MWC modelling is then applied to determine how mutations at different residues of Kir6.2 and SUR1 contribute to nucleotide binding and transduction at the inhibitory binding site.…”