Ebola and Marburg hemorrhagic fevers: neglected tropical diseases? by Adam MacNeil, Pierre E Rollin

“…Ebola hemorrhagic fever (EHF) and Marburg hemorrhagic fever (MHF) are rare viral diseases, endemic to central Africa. …”
Get full text

Serosurvey on Household Contacts of Marburg Hemorrhagic Fever Patients by Matthias Borchert, Sabue Mulangu, Robert Swanepoel, Modeste Lifenya Libande, Antoine Tshomba, Amayo Kulidri, Jean-Jacques Muyembe-Tamfum, Patrick Van der Stuyft

Subjects: “…Marburg hemorrhagic fever…”
Get full text

Response to Imported Case of Marburg Hemorrhagic Fever, the Netherlands by Aura Timen, Marion P.G. Koopmans, Ann C.T.M. Vossen, Gerard J.J. van Doornum, Stephan Günther, Franchette van den Berkmortel, Kees M. Verduin, Sabine Dittrich, Petra Emmerich, Albert D.M.E. Osterhaus, Jaap T. van Dissel, Roel A. Coutinho

“…On July 10, 2008, Marburg hemorrhagic fever was confirmed in a Dutch patient who had vacationed recently in Uganda. …”
Get full text

Risk Factors for Marburg Hemorrhagic Fever, Democratic Republic of the Congo by Daniel G. Bausch, Matthias Borchert, Thomas Grein, Cathy Roth, Robert Swanepoel, Modeste L. Libande, Antoine Talarmin, Eric Bertherat, Jean-Jacques Muyembe-Tamfum, Ben Tugume, Robert Colebunders, Kader M. Kondé, Patricia Pirard, Loku L. Olinda, Guénaël R. Rodier, Patricia Campbell, Oyewale Tomori, Thomas G. Ksiazek, Pierre E. Rollin

“…We conducted two antibody surveys to assess risk factors for Marburg hemorrhagic fever in an area of confirmed Marburg virus transmission in the Democratic Republic of the Congo. …”
Get full text

Retrospective Evaluation of Control Measures for Contacts of Patient with Marburg Hemorrhagic Fever by Aura Timen, Leslie D. Isken, Patricia Willemse, Franchette van den Berkmortel, Marion P.G. Koopmans, Danielle E.C. van Oudheusden, Chantal P. Bleeker-Rovers, Annemarie E. Brouwer, Richard P.T.M. Grol, Marlies E.J.L. Hulscher, Jaap T. van Dissel

Subjects: Get full text

Transmission potential and design of adequate control measures for Marburg hemorrhagic fever. by Marco Ajelli, Stefano Merler

“…Marburg hemorrhagic fever is rare yet among the most severe diseases affecting humans, with case fatality ratio even higher than 80%. …”
Get full text

Experimental Vaccines for Prevention of Marburg Hemorrhagic Fever and Animal Models for Studying Pathogenesis by N. V. Volkova, E. I. Kazachinskaya, D. N. Shcherbakov

Get full text

Clinical Documentation and Data Transfer from Ebola and Marburg Virus Disease Wards in Outbreak Settings: Health Care Workers’ Experiences and Preferences by Silja Bühler, Paul Roddy, Ellen Nolte, Matthias Borchert

Subjects: Get full text

Bioinformatic, Biochemical, and Immunological Mining of MHC Class I Restricted T Cell Epitopes for a Marburg Nucleoprotein Microparticle Vaccine by Paul E. Harris, Scott Burkholz, Charles V. Herst, Reid M. Rubsamen

“…The Marburg virus (MARV), the virus responsible for Marburg hemorrhagic fever (MHF), is considered a top-priority pathogen for vaccine development. …”
Get full text

Studies of Reservoir Hosts for Marburg Virus by Robert Swanepoel, Sheilagh B. Smit, Pierre E. Rollin, Pierre Formenty, Patricia A. Leman, Alan Kemp, Felicity J. Burt, Antoinette A. Grobbelaar, Janice Croft, Daniel G. Bausch, Hervé Zeller, Herwig Leirs, L.E.O. Braack, Modeste L. Libande, Sherif Zaki, Stuart T. Nichol, Thomas G. Ksiazek, Janusz T. Paweska

“…The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998–2000. We found MARV nucleic acid in 12 bats, comprising 3.0%–3.6% of 2 species of insectivorous bat and 1 species of fruit bat. …”
Get full text

Infection control during filoviral hemorrhagic fever outbreaks by N Raabe Vanessa, Borchert Matthias

“…Breaking the human-to-human transmission cycle remains the cornerstone of infection control during filoviral (Ebola and Marburg) hemorrhagic fever outbreaks. This requires effective identification and isolation of cases, timely contact tracing and monitoring, proper usage of barrier personal protection gear by health workers, and safely conducted burials. …”
Get full text

Remote-controlled and pulse pressure-guided fluid treatment for adult patients with viral hemorrhagic fevers by Schultz, MJ, Deen, J, von Seidlein, L, Sivakorn, C, Kumar, A, Adhikari, NKJ, Wills, B, Kekulé, AS, Day, NPJ, Cooper, B, White, NJ, Salam, AP, Horby, P, Olliaro, P, Dondorp, AM

“…Circulatory shock, caused by severe intravascular volume depletion resulting from gastrointestinal losses and profound capillary leak, is a common clinical feature of viral hemorrhagic fevers, including Ebola virus disease, Marburg hemorrhagic fever, and Lassa fever. These conditions are associated with high case fatality rates, and they carry a significant risk of infection for treating personnel. …”

Panmicrobial Oligonucleotide Array for Diagnosis of Infectious Diseases by Gustavo Palacios, Phenix-Lan Quan, Omar J. Jabado, Sean Conlan, David L. Hirschberg, Yang Liu, Junhui Zhai, Neil Renwick, Jeffrey Hui, Hedi Hegyi, Allen Grolla, James E. Strong, Jonathan S. Towner, Thomas W. Geisbert, Peter B. Jahrling, Cornelia Büchen-Osmond, Heinz Ellerbrok, Maria Paz Sanchez-Seco, Yves Lussier, Pierre Formenty, Stuart T. Nichol, Heinz Feldmann, Thomas Briese, W. Ian Lipkin

“…Analysis of nasopharyngeal aspirates, blood, urine, and tissue from persons with various infectious diseases confirmed the presence of viruses and bacteria identified by other methods, and implicated Plasmodium falciparum in an unexplained fatal case of hemorrhagic feverlike disease during the Marburg hemorrhagic fever outbreak in Angola in 2004–2005.…”
Get full text

Isolation of genetically diverse Marburg viruses from Egyptian fruit bats. by Jonathan S Towner, Brian R Amman, Tara K Sealy, Serena A Reeder Carroll, James A Comer, Alan Kemp, Robert Swanepoel, Christopher D Paddock, Stephen Balinandi, Marina L Khristova, Pierre B H Formenty, Cesar G Albarino, David M Miller, Zachary D Reed, John T Kayiwa, James N Mills, Deborah L Cannon, Patricia W Greer, Emmanuel Byaruhanga, Eileen C Farnon, Patrick Atimnedi, Samuel Okware, Edward Katongole-Mbidde, Robert Downing, Jordan W Tappero, Sherif R Zaki, Thomas G Ksiazek, Stuart T Nichol, Pierre E Rollin

“…In July and September 2007, miners working in Kitaka Cave, Uganda, were diagnosed with Marburg hemorrhagic fever. The likely source of infection in the cave was Egyptian fruit bats (Rousettus aegyptiacus) based on detection of Marburg virus RNA in 31/611 (5.1%) bats, virus-specific antibody in bat sera, and isolation of genetically diverse virus from bat tissues. …”
Get full text

The use of a mobile laboratory unit in support of patient management and epidemiological surveillance during the 2005 Marburg Outbreak in Angola. by Allen Grolla, Steven M Jones, Lisa Fernando, James E Strong, Ute Ströher, Peggy Möller, Janusz T Paweska, Felicity Burt, Pedro Pablo Palma, Armand Sprecher, Pierre Formenty, Cathy Roth, Heinz Feldmann

“…BACKGROUND: Marburg virus (MARV), a zoonotic pathogen causing severe hemorrhagic fever in man, has emerged in Angola resulting in the largest outbreak of Marburg hemorrhagic fever (MHF) with the highest case fatality rate to date. …”
Get full text

World Health Organization High Priority Pathogens: Ophthalmic Disease Findings and Vision Health Perspectives by Sanjana Kuthyar, Casey L. Anthony, Tolulope Fashina, Steven Yeh, Jessica G. Shantha

“…This review summarizes these key viral pathogens, summarizes major systemic disease findings, and delineates relevant ocular complications of the WHO High Priority pathogens list, including Crimean-Congo hemorrhagic fever, Filovirus diseases (Ebola virus disease and Marburg hemorrhagic fever), human Coronaviruses, Lassa Fever, Nipah virus infection, Zika, and Rift Valley fever.…”
Get full text

Viral Emerging Diseases: Challenges in Developing Vaccination Strategies by Maria Trovato, Rossella Sartorius, Luciana D’Apice, Roberta Manco, Piergiuseppe De Berardinis

“…In the last decades, a number of infectious viruses have emerged from wildlife or re-emerged, generating serious threats to the global health and to the economy worldwide. Ebola and Marburg hemorrhagic fevers, Lassa fever, Dengue fever, Yellow fever, West Nile fever, Zika, and Chikungunya vector-borne diseases, Swine flu, Severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and the recent Coronavirus disease 2019 (COVID-19) are examples of zoonoses that have spread throughout the globe with such a significant impact on public health that the scientific community has been called for a rapid intervention in preventing and treating emerging infections. …”
Get full text