Published 2018-04-01
“…Cellular analysis of the cells was carried out using Flo
Max software (Partec, Germany) in full numeric matching according to the mathematical model, which determined: G0G1 – percentage ratio of G0G1 phase cells to all cells of the cell cycle (DNA content = 2c); S – percentage ratio of the phase of DNA synthesis to all cells of the cell cycle (DNA content > 2c and < 4c); G2 + M - percentage ratio of the G2 + M phase to all cells of the cell cycle (DNA = 4c); IP - the index of proliferation, which is determined by the sum of the indices S + G2 + M; BP – block of proliferation, which is evaluated by the ratio S / (G2 + M); SUB -G0G1 is an interval on the DNA histograms RN 1 before the peak G0G1, which indicates the cell nuclei containing DNA < 2c (DNA fragmentation detection). …”
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