Natural product fragment combination to performance-diverse pseudo-natural products by Michael Grigalunas, Annina Burhop, Sarah Zinken, Axel Pahl, José-Manuel Gally, Niklas Wild, Yannik Mantel, Sonja Sievers, Daniel J. Foley, Rebecca Scheel, Carsten Strohmann, Andrey P. Antonchick, Herbert Waldmann

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A self-organized synthetic morphogenic liposome responds with shape changes to local light cues by Konstantin Gavriljuk, Bruno Scocozza, Farid Ghasemalizadeh, Hans Seidel, Akhilesh P. Nandan, Manuel Campos-Medina, Malte Schmick, Aneta Koseska, Philippe I. H. Bastiaens

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Structural basis for specific inhibition of the deubiquitinase UCHL1 by Christian Grethe, Mirko Schmidt, Gian-Marvin Kipka, Rachel O’Dea, Kai Gallant, Petra Janning, Malte Gersch

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Aminothiazolone Inhibitors Disrupt the Protein–RNA Interaction of METTL16 and Modulate the m6A RNA Modification by Yang Liu, Georg L. Goebel, Laurin Kanis, Oguz Hastürk, Claus Kemker, Peng Wu

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TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM by Markus Stabrin, Fabian Schoenfeld, Thorsten Wagner, Sabrina Pospich, Christos Gatsogiannis, Stefan Raunser

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Small-molecule screening of ribonuclease L binders for RNA degradation by Lydia Borgelt, Neele Haacke, Philipp Lampe, Xiaqiu Qiu, Raphael Gasper, Damian Schiller, Jimin Hwang, Sonja Sievers, Peng Wu

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Synthesis of Indofulvin Pseudo‐Natural Products Yields a New Autophagy Inhibitor Chemotype by Annina Burhop, Sukdev Bag, Michael Grigalunas, Sophie Woitalla, Pia Bodenbinder, Lukas Brieger, Carsten Strohmann, Axel Pahl, Sonja Sievers, Herbert Waldmann

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Spatial cycles mediated by UNC119 solubilisation maintain Src family kinases plasma membrane localisation by Antonios D. Konitsiotis, Lisaweta Roßmannek, Angel Stanoev, Malte Schmick, Philippe I. H. Bastiaens

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The pseudo GTPase CENP-M drives human kinetochore assembly by Federica Basilico, Stefano Maffini, John R Weir, Daniel Prumbaum, Ana M Rojas, Tomasz Zimniak, Anna De Antoni, Sadasivam Jeganathan, Beate Voss, Suzan van Gerwen, Veronica Krenn, Lucia Massimiliano, Alfonso Valencia, Ingrid R Vetter, Franz Herzog, Stefan Raunser, Sebastiano Pasqualato, Andrea Musacchio

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Electroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biology by Amal Alex, Valentina Piano, Soumitra Polley, Marchel Stuiver, Stephanie Voss, Giuseppe Ciossani, Katharina Overlack, Beate Voss, Sabine Wohlgemuth, Arsen Petrovic, Yaowen Wu, Philipp Selenko, Andrea Musacchio, Stefano Maffini

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Molecular basis of outer kinetochore assembly on CENP-T by Pim J Huis in 't Veld, Sadasivam Jeganathan, Arsen Petrovic, Priyanka Singh, Juliane John, Veronica Krenn, Florian Weissmann, Tanja Bange, Andrea Musacchio

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bMERB domains are bivalent Rab8 family effectors evolved by gene duplication by Amrita Rai, Anastasia Oprisko, Jeremy Campos, Yangxue Fu, Timon Friese, Aymelt Itzen, Roger S Goody, Emerich Mihai Gazdag, Matthias P Müller

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Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin by Alexander Belyy, Florian Lindemann, Daniel Roderer, Johanna Funk, Benjamin Bardiaux, Jonas Protze, Peter Bieling, Hartmut Oschkinat, Stefan Raunser

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CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading by Dongqing Pan, Kerstin Klare, Arsen Petrovic, Annika Take, Kai Walstein, Priyanka Singh, Arnaud Rondelet, Alexander W Bird, Andrea Musacchio

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Electron cryo-microscopy structure of the canonical TRPC4 ion channel by Deivanayagabarathy Vinayagam, Thomas Mager, Amir Apelbaum, Arne Bothe, Felipe Merino, Oliver Hofnagel, Christos Gatsogiannis, Stefan Raunser

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A recombinant BBSome core complex and how it interacts with ciliary cargo by Björn Udo Klink, Eldar Zent, Puneet Juneja, Anne Kuhlee, Stefan Raunser, Alfred Wittinghofer

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Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype by Gang Xue, Jianing Xie, Matthias Hinterndorfer, Marko Cigler, Lara Dötsch, Hana Imrichova, Philipp Lampe, Xiufen Cheng, Soheila Rezaei Adariani, Georg E. Winter, Herbert Waldmann

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A translational repression reporter assay for the analysis of RNA-binding protein consensus sites by Jessica Nowacki, Mateo Malenica, Stefan Schmeing, Damian Schiller, Benjamin Buchmuller, Gulshan Amrahova, Peter ‘t Hart

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The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members by Amrita Rai, Nathalie Bleimling, Ingrid R. Vetter, Roger S. Goody

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Towards the application of Tc toxins as a universal protein translocation system by Daniel Roderer, Evelyn Schubert, Oleg Sitsel, Stefan Raunser

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