Metabolic switch from fatty acid oxidation to glycolysis in knock‐in mouse model of Barth syndrome by Arpita Chowdhury, Angela Boshnakovska, Abhishek Aich, Aditi Methi, Ana Maria Vergel Leon, Ivan Silbern, Christian Lüchtenborg, Lukas Cyganek, Jan Prochazka, Radislav Sedlacek, Jiri Lindovsky, Dominic Wachs, Zuzana Nichtova, Dagmar Zudova, Gizela Koubkova, André Fischer, Henning Urlaub, Britta Brügger, Dörthe M Katschinski, Jan Dudek, Peter Rehling

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Editorial: One health care in psychiatric and neurological diseases by Júlio Belo Fernandes, Júlio Belo Fernandes, Cristina Baixinho, Cristina Baixinho, Tiago F. Outeiro, Tiago F. Outeiro, Tiago F. Outeiro, Tiago F. Outeiro, Catarina Godinho, Catarina Godinho

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The immune system in Parkinson's disease: From biology to diagnosis and therapeutic targets by Tiago Fleming Outeiro, Omar M. El-Agnaf

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Cas1 and Fen1 Display Equivalent Functions During Archaeal DNA Repair by Julia Wörtz, Victoria Smith, Jörg Fallmann, Sabine König, Sabine König, Tharani Thuraisingam, Paul Walther, Henning Urlaub, Henning Urlaub, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Thorsten Allers, Frank Hille, Anita Marchfelder

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Presynaptic Rac1 controls synaptic strength through the regulation of synaptic vesicle priming by Christian Keine, Mohammed Al-Yaari, Tamara Radulovic, Connon I Thomas, Paula Valino Ramos, Debbie Guerrero-Given, Mrinalini Ranjan, Holger Taschenberger, Naomi Kamasawa, Samuel M Young Jr

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Central cavity dehydration as a gating mechanism of potassium channels by Ruo-Xu Gu, Bert L. de Groot

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Extensive Bioinformatics Analyses Reveal a Phylogenetically Conserved Winged Helix (WH) Domain (Zτ) of Topoisomerase IIα, Elucidating Its Very High Affinity for Left-Handed Z-DNA a... by Martin Bartas, Kristyna Slychko, Jiří Červeň, Petr Pečinka, Donna J. Arndt-Jovin, Thomas M. Jovin

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Distinct but overlapping roles of LRRTM1 and LRRTM2 in developing and mature hippocampal circuits by Shreya H Dhume, Steven A Connor, Fergil Mills, Parisa Karimi Tari, Sarah HM Au-Yeung, Benjamin Karimi, Shinichiro Oku, Reiko T Roppongi, Hiroshi Kawabe, Shernaz X Bamji, Yu Tian Wang, Nils Brose, Michael F Jackson, Ann Marie Craig, Tabrez J Siddiqui

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Exosomes in skin photoaging: biological functions and therapeutic opportunity by Amirhossein Hajialiasgary Najafabadi, Mohammad Hasan Soheilifar, Nastaran Masoudi-Khoram

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Acetylation discriminates disease-specific tau deposition by Pijush Chakraborty, Gwladys Rivière, Alina Hebestreit, Alain Ibáñez de Opakua, Ina M. Vorberg, Loren B. Andreas, Markus Zweckstetter

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Editorial: Personalized care in neurological diseases by Júlio Belo Fernandes, Júlio Belo Fernandes, Júlio Belo Fernandes, Catarina Godinho, Catarina Godinho, Catarina Godinho, Tiago F. Outeiro, Tiago F. Outeiro, Tiago F. Outeiro, Tiago F. Outeiro, Cristina Lavareda Baixinho, Cristina Lavareda Baixinho

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Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein by Benedikt Frieg, James A. Geraets, Timo Strohäker, Christian Dienemann, Panagiota Mavroeidi, Byung Chul Jung, Woojin S. Kim, Seung-Jae Lee, Maria Xilouri, Markus Zweckstetter, Gunnar F. Schröder

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Uncovering the temporal dynamics and regulatory networks of thermal stress response in a hyperthermophile using transcriptomics and proteomics by Felix Grünberger, Georg Schmid, Zubeir El Ahmad, Martin Fenk, Katharina Vogl, Robert Reichelt, Winfried Hausner, Henning Urlaub, Christof Lenz, Dina Grohmann

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The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3’-UTR and promoting Rag1 mRNA expression by Meng Xu, Taku Ito-Kureha, Hyun-Seo Kang, Aleksandar Chernev, Timsse Raj, Kai P. Hoefig, Christine Hohn, Florian Giesert, Yinhu Wang, Wenliang Pan, Natalia Ziętara, Tobias Straub, Regina Feederle, Carolin Daniel, Barbara Adler, Julian König, Stefan Feske, George C. Tsokos, Wolfgang Wurst, Henning Urlaub, Michael Sattler, Jan Kisielow, F. Gregory Wulczyn, Marcin Łyszkiewicz, Vigo Heissmeyer

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Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient‐induced pluripotent stem cell‐derived retinal pigment epithelium cells by Maria Georgiou, Chunbo Yang, Robert Atkinson, Kuan‐Ting Pan, Adriana Buskin, Marina Moya Molina, Joseph Collin, Jumana Al‐Aama, Franziska Goertler, Sebastian E. J. Ludwig, Tracey Davey, Reinhard Lührmann, Sushma Nagaraja‐Grellscheid, Colin A. Johnson, Robin Ali, Lyle Armstrong, Viktor Korolchuk, Henning Urlaub, Sina Mozaffari‐Jovin, Majlinda Lako

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BAF (mSWI/SNF) complex regulates mediolateral cortical patterning in the developing forebrain by Huong Nguyen, Huong Nguyen, Godwin Sokpor, Godwin Sokpor, Godwin Sokpor, Arpan Parichha, Linh Pham, Linh Pham, Nidhi Saikhedkar, Yuanbin Xie, Pauline Antonie Ulmke, Pauline Antonie Ulmke, Joachim Rosenbusch, Mehdi Pirouz, Mehdi Pirouz, Rüdiger Behr, Anastassia Stoykova, Beate Brand-Saberi, Huu Phuc Nguyen, Jochen F. Staiger, Shubha Tole, Tran Tuoc, Tran Tuoc

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Hypoxia Sensing and Responses in Parkinson’s Disease by Johannes Burtscher, Yves Duderstadt, Hannes Gatterer, Martin Burtscher, Roman Vozdek, Grégoire P. Millet, Andrew A. Hicks, Hannelore Ehrenreich, Martin Kopp

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Deciphering the molecular functionality of Cdc45 in replisomal complex by Arathi Radhakrishnan, Chandresh Sharma, Viveka Nand Malviya, Rajpal Srivastav

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Multivalent Tau/PSD-95 interactions arrest in vitro condensates and clusters mimicking the postsynaptic density by Zheng Shen, Daxiao Sun, Adriana Savastano, Sára Joana Varga, Maria-Sol Cima-Omori, Stefan Becker, Alf Honigmann, Markus Zweckstetter

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The Hidden Role of Non-Canonical Amyloid β Isoforms in Alzheimer’s Disease by Lukas Busch, Simone Eggert, Kristina Endres, Bernd Bufe

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