Scoping Review of Off-Label Topical Analgesia in Palliative, Hospice and Cancer Care: Towards Flexibility in Evidence-Based Medicine by Tayeb BO, Winegarden JA, Alashari RA, Alasmari M, Winegarden J, Boker F, Halawi A, Lapidow A, Bradshaw YS, Carr DB

“…Baraa O Tayeb,1,2 Jennifer A Winegarden,3 Rawabi A Alashari,4,5 Moudi Alasmari,6,7 Jonathan Winegarden,8 Faisal Boker,9 Abdulaziz Halawi,2 Amy Lapidow,10 Ylisabyth S Bradshaw,11 Daniel B Carr11 1Department of Anesthesiology and Critical Care, King Abdulaziz University Faculty of Medicine, Jeddah, Saudi Arabia; 2King Abdulaziz University Hospital, Jeddah, Saudi Arabia; 3Department of Medicine, The Medical Team Hospice, Livonia, MI, USA; 4Department of Pharmacology, King Abdulaziz University, Faculty of Medicine, Jeddah, Saudi Arabia; 5Department of Pharmaceutical Science, MCPHS University, Boston, MA, USA; 6College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia; 7King Abdullah International Medical Research Center (KAIMRC), Jeddah, Saudi Arabia; 8Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA; 9Emergency Department, King Abdulaziz Medical City-Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia; 10Tufts Hirsh Health Sciences Library, Boston, MA, USA; 11Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USACorrespondence: Baraa O TayebFaculty of Medicine, King Abdulaziz University, P.B. …”
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Comparative diagnostic accuracy of EUS needles in solid pancreatic masses: a network meta-analysis by Samuel Han, Furqan Bhullar, Omar Alaber, Ayesha Kamal, Puanani Hopson, Kavin Kanthasamy, Sarah Coughlin, Livia Archibugi, Nikhil Thiruvengadam, Christopher Moreau, David Jin, Pedram Paragomi, Francisco Valverde-López, Sajan Nagpal, Cemal Yazici, Georgios Papachristou, Peter J Lee, Venkata Akshintala

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Safety and efficacy of liquid nitrogen spray cryotherapy in Barrett’s neoplasia – a comprehensive review and meta-analysis by Saurabh Chandan, Jay Bapaye, Shahab R. Khan, Smit Deliwala, Babu P. Mohan, Daryl Ramai, Banreet S. Dhindsa, Hemant Goyal, Lena L. Kassab, Muhammad Aziz, Faisal Kamal, Antonio Facciorusso, Douglas G. Adler

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International Consensus (ICON): allergic reactions to vaccines by Stephen C. Dreskin, Neal A. Halsey, John M. Kelso, Robert A. Wood, Donna S. Hummell, Kathryn M. Edwards, Jean-Christoph Caubet, Renata J.M. Engler, Michael S. Gold, Claude Ponvert, Pascal Demoly, Mario Sanchez-Borges, Antonella Muraro, James T. Li, Menachem Rottem, Lanny J. Rosenwasser

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Artificial intelligence-assisted clinical decision support for childhood asthma management: A randomized clinical trial. by Hee Yun Seol, Pragya Shrestha, Joy Fladager Muth, Chung-Il Wi, Sunghwan Sohn, Euijung Ryu, Miguel Park, Kathy Ihrke, Sungrim Moon, Katherine King, Philip Wheeler, Bijan Borah, James Moriarty, Jordan Rosedahl, Hongfang Liu, Deborah B McWilliams, Young J Juhn

“…<h4>Methods</h4>This was a single-center pragmatic RCT with a stratified randomization design conducted for one year in the primary care pediatric practice of the Mayo Clinic, MN. Children (<18 years) diagnosed with asthma receiving care at the study site were enrolled along with their 42 primary care providers. …”
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Phase I study of PT-112, a novel pyrophosphate-platinum immunogenic cell death inducer, in advanced solid tumours by Daniel D. Karp, D. Ross Camidge, Jeffery R. Infante, Tyler D. Ames, Matthew R. Price, José Jimeno, Alan H. Bryce

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Liraglutide to Improve corONary haemodynamics during Exercise streSS (LIONESS): a double-blind randomised placebo-controlled crossover trial by Aung Myat, Simon R. Redwood, Satpal Arri, Bernard J. Gersh, Deepak L. Bhatt, Michael S. Marber

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Differential diagnosis of frontotemporal dementia subtypes with explainable deep learning on structural MRI by Da Ma, Jane Stocks, Howard Rosen, Kejal Kantarci, Samuel N. Lockhart, James R. Bateman, Suzanne Craft, Metin N. Gurcan, Karteek Popuri, Mirza Faisal Beg, Lei Wang, Lei Wang, on behalf of the ALLFTD consortium

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Relationship Among Clinically Obtained Biomarkers of Inflammation, Hypercoagulability, and Macrophage Activation, and Delirium in Critically Ill Patients With COVID-19 by Sikandar H. Khan, DO, MS, Anthony J. Perkins, MS, Rosalyn Chi, MD, Sarah Seyffert, MD, Peter Conrad, MD, Heidi Lindroth, PhD, RN, Sophia Wang, MD, Malissa Mulkey, PhD, APRN, CCNS, CCRN, CNRN, Sujuan Gao, PhD, Babar Khan, MD, MS

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UNet Deep Learning Architecture for Segmentation of Vascular and Non-Vascular Images: A Microscopic Look at UNet Components Buffered With Pruning, Explainable Artificial Intelligen... by Jasjit S. Suri, Mrinalini Bhagawati, Sushant Agarwal, Sudip Paul, Amit Pandey, Suneet K. Gupta, Luca Saba, Kosmas I. Paraskevas, Narendra N. Khanna, John R. Laird, Amer M. Johri, Manudeep K. Kalra, Mostafa M. Fouda, Mostafa Fatemi, Subbaram Naidu

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Posttransplant Diabetes Mellitus and Immunosuppression Selection in Older and Obese Kidney RecipientsPlain-Language Summary by David A. Axelrod, Wisit Cheungpasitporn, Suphamai Bunnapradist, Mark A. Schnitzler, Huiling Xiao, Mara McAdams-DeMarco, Yasar Caliskan, Sunjae Bae, JiYoon B. Ahn, Dorry L. Segev, Ngan N. Lam, Gregory P. Hess, Krista L. Lentine

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Outpatient and inpatient anticoagulation therapy and the risk for hospital admission and death among COVID-19 patients by Sameh M. Hozayen, Diana Zychowski, Sydney Benson, Pamela L. Lutsey, Jasmin Haslbauer, Alexandar Tzankov, Zachary Kaltenborn, Michael Usher, Surbhi Shah, Christopher J. Tignanelli, Ryan T. Demmer

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Corticosteroids in Sepsis and Septic Shock: A Systematic Review, Pairwise, and Dose-Response Meta-Analysis by Tyler Pitre, MD, MA, Katherine Drover, Dipayan Chaudhuri, MD, MSc, Dena Zeraaktkar, PhD, Kusum Menon, MD, MSc, Hayley B. Gershengorn, MD, Namita Jayaprakash, MD, Joanna L. Spencer-Segal, MD, PhD, Stephen M. Pastores, MD, Andrea M. Nei, PharmD, Djillali Annane, MD, PhD, Bram Rochwerg, MD, MSc

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Real-world experience of patients with multiple myeloma receiving ide-cel after a prior BCMA-targeted therapy by Christopher J. Ferreri, Michelle A. T. Hildebrandt, Hamza Hashmi, Leyla O. Shune, Joseph P. McGuirk, Douglas W. Sborov, Charlotte B. Wagner, M. Hakan Kocoglu, Aaron Rapoport, Shebli Atrash, Peter M. Voorhees, Jack Khouri, Danai Dima, Aimaz Afrough, Gurbakhash Kaur, Larry D. Anderson, Gary Simmons, James A. Davis, Nilesh Kalariya, Lauren C. Peres, Yi Lin, Murali Janakiram, Omar Nadeem, Melissa Alsina, Frederick L. Locke, Surbhi Sidana, Doris K. Hansen, Krina K. Patel, Omar Alexis Castaneda Puglianini

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Long-acting dolutegravir formulations prevent neurodevelopmental impairments in a mouse model by Emma G. Foster, Brady Sillman, Yutong Liu, Micah Summerlin, Vikas Kumar, Balasrinivasa R. Sajja, Adam R. Cassidy, Benson Edagwa, Howard E. Gendelman, Howard E. Gendelman, Aditya N. Bade

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Isoliquiritigenin from licorice root: A multi-stage anti-malarial with synergistic impact on multidrug-resistant P. falciparum by Saurabh Kumar, Deepak Singh kapkoti, Pooja Rani Mina, Divya Bhatt, Parmanand Kumar, Manju Singh, Karuna Shanker, Dnyaneshwar Umrao Bawankule, Rajendra Singh Bhakuni, Anirban Pal, Mahendra P. Darokar

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Erratum to Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized co... by T. Bluth, R. Teichmann, T. Kiss, I. Bobek, J. Canet, G. Cinnella, L. De Baerdemaeker, C. Gregoretti, G. Hedenstierna, S. N. Hemmes, M. Hiesmayr, M. W. Hollmann, S. Jaber, J. G. Laffey, M. J. Licker, K. Markstaller, I. Matot, G. Müller, G. H. Mills, J. P. Mulier, C. Putensen, R. Rossaint, J. Schmitt, M. Senturk, A. Serpa Neto, P. Severgnini, J. Sprung, M. F. Vidal Melo, H. Wrigge, M. J. Schultz, P. Pelosi, Marcelo Gama de Abreu, for the PROBESE investigators, and the PROtective VEntilation Network (PROVEnet) and on behalf of the Clinical Trial Network of the European Society of Anaesthesiology (ESA)

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Clinical Amyloid Typing by Proteomics: Performance Evaluation and Data Sharing between Two Centres by Diana Canetti, Francesca Brambilla, Nigel B. Rendell, Paola Nocerino, Janet A. Gilbertson, Dario Di Silvestre, Andrea Bergamaschi, Francesca Lavatelli, Giampaolo Merlini, Julian D. Gillmore, Vittorio Bellotti, Pierluigi Mauri, Graham W. Taylor

“…Proteomic analysis of patients’ biopsies, developed by Dogan and colleagues at the Mayo Clinic, has become crucial for clinical diagnosis and for identifying the amyloid type. …”
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Corrigendum: Thrombotic Microangiopathy in the Renal Allograft: Results of the TMA Banff Working Group Consensus on Pathologic Diagnostic Criteria by Marjan Afrouzian, Nicolas Kozakowski, Helen Liapis, Verena Broecker, Luon Truong, Carmen Avila-Casado, Heinz Regele, Surya Seshan, Josephine M. Ambruzs, Alton Brad Farris, David Buob, Praveen N. Chander, Lukman Cheraghvandi, Marian C. Clahsen-van Groningen, Marian C. Clahsen-van Groningen, Stanley de Almeida Araujo, Dilek Ertoy Baydar, Mark Formby, Mark Formby, Danica Galesic Ljubanovic, Loren Herrera Hernandez, Eva Honsova, Nasreen Mohamed, Yasemin Ozluk, Marion Rabant, Virginie Royal, Heather L. Stevenson, Maria Fernanda Toniolo, Diana Taheri, Diana Taheri

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Increased RV:LV ratio on chest CT-angiogram in COVID-19 is a marker of adverse outcomes by Ran Tao, Zuzana Burivalova, S. Carolina Masri, Naga Dharmavaram, Aurangzeb Baber, Roderick Deaño, Timothy Hess, Ravi Dhingra, James Runo, Nizar Jarjour, Rebecca R. Vanderpool, Naomi Chesler, Joanna E. Kusmirek, Marlowe Eldridge, Christopher Francois, Farhan Raza

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