Exposure to surgery with regional anesthesia and cortical thickness in older adults by Juraj Sprung, David S. Knopman, Ronald C. Petersen, Prashanthi Vemuri, Michelle M. Mielke, Toby N. Weingarten, Phillip J. Schulte, Darrell R. Schroeder, David O. Warner

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Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis by Donglin Ding, Alexandra M. Blee, Jianong Zhang, Yunqian Pan, Nicole A. Becker, L. James Maher, Rafael Jimenez, Liguo Wang, Haojie Huang

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Retinoblastoma protein as an intrinsic BRD4 inhibitor modulates small molecule BET inhibitor sensitivity in cancer by Donglin Ding, Rongbin Zheng, Ye Tian, Rafael Jimenez, Xiaonan Hou, Saravut J. Weroha, Liguo Wang, Lei Shi, Haojie Huang

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Reimagining Learning Spaces of the Future: An Interprofessional, Virtual Workshop Utilizing Rapid Idea Generation and Lean Startup Methodologies by Heather Billings, Theresa Malin, Jennifer Allen, Angela Bergene, Katherine Cornelius, Stacy Craft, Lisa Hartzheim, Stacy A. Johnson, Jennifer Kallay, Justin Kreuter, Michelle Raths, Amy Seegmiller Renner, Elissa Hall

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Noncanonical TRAIL Signaling Promotes Myeloid-Derived Suppressor Cell Abundance and Tumor Growth in CholangiocarcinomaSummary by Emilien J. Loeuillard, Binbin Li, Hannah E. Stumpf, Jingchun Yang, Jessica R. Willhite, Jennifer L. Tomlinson, Fred Rakhshan Rohakhtar, Vernadette A. Simon, Rondell P. Graham, Rory L. Smoot, Haidong Dong, Sumera I. Ilyas

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Ultrasound Radiation Force for the Assessment of Bone Fracture Healing in Children: An In Vivo Pilot Study by Siavash Ghavami, Adriana Gregory, Jeremy Webb, Mahdi Bayat, Max Denis, Viksit Kumar, Todd A. Milbrand, A. Noelle Larson, Mostafa Fatemi, Azra Alizad

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SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition by Jian Ma, Qing Shi, Gaofeng Cui, Haoyue Sheng, Maria Victoria Botuyan, Yingke Zhou, Yuqian Yan, Yundong He, Liguo Wang, Yuzhuo Wang, Georges Mer, Dingwei Ye, Chenji Wang, Haojie Huang

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Combined Antitumor Effect of the Serine Protease Urokinase Inhibitor Upamostat and the Sphingosine Kinase 2 Inhibitor Opaganib on Cholangiocarcinoma Patient-Derived Xenografts by Faizal Z. Asumda, Nellie A. Campbell, Mohamed A. Hassan, Reza Fathi, Daniella F. Vasquez Rico, Melanie Kiem, Ethan V. Vang, Yo Han Kim, Xin Luo, Daniel R. O’Brien, Sarah A. Buhrow, Joel M. Reid, Michael J. Moore, Vered Katz Ben-Yair, Mark L. Levitt, Jennifer L. Leiting, Amro M. Abdelrahman, Xinli Zhu, Fabrice Lucien, Mark J. Truty, Lewis R. Roberts

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A Knowledge-Based Discovery Approach Couples Artificial Neural Networks With Weight Engineering to Uncover Immune-Related Processes Underpinning Clinical Traits of Breast Cancer by Cheng Zhang, Cristina Correia, Taylor M. Weiskittel, Shyang Hong Tan, Kevin Meng-Lin, Grace T. Yu, Jingwen Yao, Kok Siong Yeo, Shizhen Zhu, Choong Yong Ung, Hu Li

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Teaming beyond the clinical environment – building collective commitment across graduate medical education by Brady S. Laughlin, Elaine M. Griffeth, Aaron F. Bush, Cheryll A. Albold, Christopher J. Boes, Annie T. Sadosty

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Comparison of emergency department throughput and process times between male and female patients: A retrospective cohort investigation by the Reducing Disparities Increasing Equity... by Ege G. Onal, Kit Knier, Alexander W. Hunt, John M. Knudsen, David M. Nestler, Ronna L. Campbell, Kristine M. Thompson, Kharmene L. Sunga, Laura E. Walker, Bo E. Madsen, Annie T. Sadosty, Alyson J. McGregor, Aidan F. Mullan, Molly M. Jeffery, Venkatesh R. Bellamkonda

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Predictors of Treatment Failure in Patients With Pyogenic Brain Abscess by Cristina Corsini Campioli, John C. O’Horo, Brian D. Lahr, Walter R. Wilson, Daniel C. DeSimone, Larry M. Baddour, Jamie J. Van Gompel, M. Rizwan Sohail

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Tissue-Resident Macrophages Limit Pulmonary CD8 Resident Memory T Cell Establishment by Nick P. Goplen, Su Huang, Bibo Zhu, In Su Cheon, Young Min Son, Zheng Wang, Chaofan Li, Qigang Dai, Li Jiang, Jie Sun, Jie Sun

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Cytochrome P450 2C19 Poor Metabolizer Phenotype in Treatment Resistant Depression: Treatment and Diagnostic Implications by Marin Veldic, Ahmed T. Ahmed, Caren J. Blacker, Jennifer R. Geske, Joanna M. Biernacka, Joanna M. Biernacka, Kristin L. Borreggine, Katherine M. Moore, Miguel L. Prieto, Miguel L. Prieto, Jennifer L. Vande Voort, Paul E. Croarkin, Astrid A. Hoberg, Simon Kung, Renato D. Alarcon, Renato D. Alarcon, Nicola Keeth, Balwinder Singh, William V. Bobo, Mark A. Frye

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Chronic Alcohol Exposure Induces Aberrant Mitochondrial Morphology and Inhibits Respiratory Capacity in the Medial Prefrontal Cortex of Mice by Pei Shang, Pei Shang, Daniel Lindberg, Phillip Starski, Lee Peyton, Sa-Ik Hong, Sun Choi, Doo-Sup Choi, Doo-Sup Choi, Doo-Sup Choi

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Coronary Endothelial Dysfunction Is Associated With Increased Risk of Incident Atrial Fibrillation by Michel T. Corban, Shigeo Godo, Daniel R. Burczak, Peter A. Noseworthy, Takumi Toya, Bradley R. Lewis, Lilach O. Lerman, Rajiv Gulati, Amir Lerman

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SPOP mutation induces DNA methylation via stabilizing GLP/G9a by Jianong Zhang, Kun Gao, Hongyan Xie, Dejie Wang, Pingzhao Zhang, Ting Wei, Yuqian Yan, Yunqian Pan, Wenbin Ye, Huifen Chen, Qing Shi, Yao Li, Shi-min Zhao, Xiaonan Hou, Saravut J. Weroha, Yuzhuo Wang, Jun Zhang, R. Jeffrey Karnes, Housheng Hansen He, Liguo Wang, Chenji Wang, Haojie Huang

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Automated Segmentation of Thyroid Nodule, Gland, and Cystic Components From Ultrasound Images Using Deep Learning by Viksit Kumar, Jeremy Webb, Adriana Gregory, Duane D. Meixner, John M. Knudsen, Matthew Callstrom, Mostafa Fatemi, Azra Alizad

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Morphometric analysis of tumor microvessels for detection of hepatocellular carcinoma using contrast-free ultrasound imaging: A feasibility study by Soroosh Sabeti, Redouane Ternifi, Nicholas B. Larson, Michael C. Olson, Thomas D. Atwell, Mostafa Fatemi, Azra Alizad, Azra Alizad

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Dissecting VEGF-induced acute versus chronic vascular hyperpermeability: Essential roles of dimethylarginine dimethylaminohydrolase-1 by Ying Wang, Ramcharan Singh Angom, Tanmay A. Kulkarni, Luke H. Hoeppner, Krishnendu Pal, Enfeng Wang, Alexander Tam, Rachael A. Valiunas, Shamit K. Dutta, Baoan Ji, Natalia Jarzebska, Yingjie Chen, Roman N. Rodionov, Debabrata Mukhopadhyay

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