Regulation of the hif-1-dependent hypoxic stress response by C. elegans by Diehl, Calista Sorine

“…First, we discovered that loss of the conserved nonsense-mediated decay (NMD) pathway, an RNA surveillance mechanism that degrades aberrant mRNA transcripts with premature termination codons, suppressed the egl-9(lf)-induced changes in egg laying and defecation and caused increased hypoxia sensitivity. …”
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Targeted hematopoietic stem cell depletion through SCF-blockade by Chan, Yan Y., Ho, Pui Y., Dib, Carla, Swartzrock, Leah, Rayburn, Maire, Willner, Hana, Ko, Ethan, Ho, Katie, Down, Julian D., Wilkinson, Adam C., Nakauchi, Hiro, Denis, Morgane, Cool, Taylor, Czechowicz, Agnieszka

“…Conclusion These findings shed new insights into the mechanism of αCD117 mAb-mediated HSC depletion. Further, they highlight multiple approaches for efficacy in SCID settings and optimal combinations for WT settings. …”
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Beyond Color: Lattice Gauge Theory for Strongly-Coupled Physics by Oare, Patrick R.

“…Lattice methods are used to compute the static quark potential, string tensions, and the low-lying spectrum of the theory, which will provide input that may be used to understand better QCD₂ and the confinement mechanism in general.…”
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P2P energy trading among isolated microgrids in the remote area by Huang, Rui

“…Combining with the emission standard of carbon allowance, the incentive mechanism of each MG is set to improve the robustness of the model and the rationality of each MG while trading. …”
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Learning-based robot navigation in dynamic environments: from indoor scenes to human crowd scenes by Jiang, Haoge

“…It models the environment information in a graph representation and employs a Message-Passing Graph Convolutional Network (MP-GCN) with edge-wise gating mechanisms to encode asymmetric human-human and human-robot interactions. …”
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Modeling and analysis of device-to-device communications and interference management in heterogeneous cellular networks by Afshang, Mehrnaz

“…The effects of the proposed interference mitigation mechanisms on the whole network are captured by modeling the locations of transmitters as a Poisson hole process. …”
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Engineering memristor : control over the fourth fundamental element for memory application and beyond by Ge, Ning

“…However, until today many fundamental questions, including an accurate understanding of the switching mechanism, availability for high quality selector devices, and implementation the fundamental element to the novel circuit design etc., are still in question. …”
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Novel nitric oxide donors for the dispersal and control of Pseudomonas aeruginosa biofilms by Poh, Wee Han

“…Two purified proteins, DipA and RbdA, were not found to act as sensors of NO, and are likely to be involved in the dispersal process through other mechanisms. Using a batch microplate system for biofilm dispersal, transposon mutants of several genes previously shown to be defective in dispersal in flow systems, were unexpectedly found to be unaffected in NO induced dispersal, indicating that there may be genetic redundancies and that the response to NO and that NO induced dispersal may be additionally regulated by the growth conditions.…”
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Screen printed quinone-derivatives-based carbon electrode : a novel universal voltammetric pH sensor in buffered and unbuffered solution by Karya, Arthur Bentus

“…Alizarin, TMNW and DMQ are suggested to have 2e-,2H+ redox mechanism with probable electron hopping and in-film diffusion suggested for 3 layer thickness kinetics. …”
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Analysis of high power gallium nitride based high electron mobility transistors for next generation electronics applications by Vompolu, Ganesh Sampath

“…It is also widely recognized that, the semiconductor devices which can function at ambient temperatures beyond 150°C without any external cooling mechanisms can very well help a lot of future electronics applications in the fields of aerospace, automotive, energy production, etc. …”
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Words and facts: children's fast mapping, retention and extension by Holland, Amanda

“…This indicated that facts can be as extendable as words and supports the conclusion that learning words and facts utilize similar cognitive mechanisms.…”
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Reverse translational approaches to population neuroimaging: using rodent models to interpret genetic associations with MRI by Tisca, C

“…</p> <p>To investigate the biological mechanisms driving the observed MRI signal changes, we conducted multi-modal <em>ex-vivo</em> MRI and histology studies in <em>Vcan</em> and <em>Bcan</em> mouse models.…”

Acquisition of musical skills and abilities in older adults—results of 12 months of music training by Losch, H, Altenmüller, E, Marie, D, Passarotto, E, Kretschmer, CR, Scholz, DS, Kliegel, M, Krüger, THC, Sinke, C, Jünemann, K, James, CE, Worschech, F

“…Practicing a musical instrument has been identified as a promising activity for improving cognition, promoting well-being, and inducing brain plasticity in older individuals. However, the mechanisms of these changes are still poorly understood. …”

The molecular determinants of Polycomb-mediated gene repression by Fursova, N

“…Elucidating the molecular mechanisms of Polycomb-mediated transcriptional silencing has proven challenging, as both PRC1 and PRC2 exist as an array of protein assemblies with distinct targeting modules and regulatory activities. …”

Electronic structure of topological quantum materials probed by angle-resolved photoelectron spectroscopy by Schröter, N

“…For the superconducting hole doped Sr₃SnO, which may realize unconventional odd-parity Cooper pairing, we can resolve a controversial question about its Fermi surface morphology that may be relevant for its pairing mechanism.</p>…”

Distinctive antibody responses to Mycobacterium tuberculosis in pulmonary and brain infection by Spatola, M, Nziza, N, Irvine, EB, Cizmeci, D, Jung, W, Van, LH, Nhat, LTH, Ha, VTN, Phu, NH, Nghia, HDT, Thwaites, GE, Lauffenburger, DA, Fortune, S, Thuong, NTT, Alter, G

“…However, little is known about the immunological mechanisms that lead to differential disease across organs. …”

The relationship between leisure time physical activity patterns, Alzheimer’s disease markers and cognition by James, S, Sudre, CH, Barnes, J, Cash, DM, Chiou, Y, Coath, W, Keshavan, A, Lu, K, Malone, I, Murray-Smith, H, Nicholas, JM, Orini, M, Parker, T, Almeida-Meza, P, Fox, NC, Richards, M, Schott, JM

“…Our findings warrant further research to shed light on the mechanisms of physical activity as a potential disease-modifying intervention of brain health and cognitive resilience.…”

Assessment of novel pre-erythrocytic malaria vaccines in humans by Venkatraman, N

“…In addition to humoral immunity, it is widely recognised that T-cell mechanisms are likely to play an important role in malaria immunity and heterologous prime-boost regimes using viral-vectored vaccines have been shown to induce potent T-cell responses. …”

Exploring employee working productivity: initial insights from machine learning predictive analytics and visualization by Razali, Mohd Norhisham, Ibrahim, Norizuandi, Hanapi, Rozita, Mohd Zamri, Norfarahzila, Abdul Manaf, Syaifulnizam

“…Subjective assessments, numerous assessment factors, and difficulties in interpreting predictive mechanisms add to the complexity of the task. To address these challenges, this research aims to develop a predictive model using machine learning techniques to determine employee productivity within organizations. …”
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Phytochemical analysis and cytotoxic effects of mango (Mangifera indica L) kernel on breast cancer cell lines by Abdullah, Al-Shwyeh Hussah

“…The effects of the extract on apoptosis-related markers (Bcl-2, Bax, p53 proteins and Caspase-3, -8 and -9) were also assessed to determine mechanism of cell death. The results showed that M. indica waterlily kernel extract has many bioactive compounds especially phenolics such as phenolic acid, flavonoides and xanthones. …”
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