Chitosan-silica Sulfate Nano Hybrid: An Efficient Biopolymer Based-heterogeneous Nano Catalyst for Solvent-free Synthesis of 3,4-Dihydropyrimidine-2(1H)-one/thiones by Somayeh Behrouz, Masoome Nazar Abi, Mohammad Amin Piltan

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Novel indole derivatives as hepatitis C virus NS5B polymerase inhibitors: Pharmacophore modeling and 3D QSAR studies by G. Varun, M. Lokesh, M. Sandeep, Sajad Shahbazi, Deepak Reddy Gade

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A novel three-component reaction between isocyanides, alcohols or thiols and elemental sulfur: a mild, catalyst-free approach towards O-thiocarbamates and dithiocarbamates by András György Németh, György Miklós Keserű, Péter Ábrányi-Balogh

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Fragment-Sized and Bidentate (Immuno)Proteasome Inhibitors Derived from Cysteine and Threonine Targeting Warheads by Levente Kollár, Martina Gobec, Matic Proj, Lara Smrdel, Damijan Knez, Tímea Imre, Ágnes Gömöry, László Petri, Péter Ábrányi-Balogh, Dorottya Csányi, György G. Ferenczy, Stanislav Gobec, Izidor Sosič, György M. Keserű

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Unravelling the Allosteric Targeting of PHGDH at the ACT-Binding Domain with a Photoactivatable Diazirine Probe and Mass Spectrometry Experiments by Quentin Spillier, Séverine Ravez, Simon Dochain, Didier Vertommen, Léopold Thabault, Olivier Feron, Raphaël Frédérick

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Synthesis and antimicrobial activities of 1-(3-benzyl-4-oxo-3H-quinazolin-2-yl)-4-(substituted)thiosemicarbazide derivatives by Alagarsamy Veerachamy, Solomon Viswas Raja, Krishnamoorthy G., Sulthana M.T., Narendar B.

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Machine learning/molecular dynamic protein structure prediction approach to investigate the protein conformational ensemble by Martina Audagnotto, Werngard Czechtizky, Leonardo De Maria, Helena Käck, Garegin Papoian, Lars Tornberg, Christian Tyrchan, Johan Ulander

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Global Analysis of Deep Learning Prediction Using Large-Scale In-House Kinome-Wide Profiling Data by Hirotomo Moriwaki, Shin Saito, Tomoya Matsumoto, Takayuki Serizawa, Ryo Kunimoto

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Development of a Manufacturing Process toward the Convergent Synthesis of the COVID-19 Antiviral Ensitrelvir by Takahiro Kawajiri, Akihito Kijima, Atsuhiro Iimuro, Eisaku Ohashi, Katsuya Yamakawa, Kazushi Agura, Kengo Masuda, Kensuke Kouki, Koji Kasamatsu, Shuichi Yanagisawa, Sho Nakashima, Setsuya Shibahara, Takashi Toyota, Takafumi Higuchi, Takahiro Suto, Tadashi Oohara, Toshikatsu Maki, Naoto Sahara, Nobuaki Fukui, Hisayuki Wakamori, Hidaka Ikemoto, Hiroaki Murakami, Hiroyasu Ando, Masahiro Hosoya, Mizuki Sato, Yusuke Suzuki, Yuta Nakagawa, Yuto Unoh, Yoichi Hirano, Yoshitomo Nagasawa, Satoshi Goda, Takafumi Ohara, Takayuki Tsuritani

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Combretastatin A-4 based thiophene derivatives as antitumor agent: Development of structure activity correlation model using 3D-QSAR, pharmacophore and docking studies by Vijay K. Patel, Avineesh Singh, Deepak K. Jain, Preeti Patel, Ravichandran Veerasamy, Prabodh C. Sharma, Harish Rajak

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Gymnotic uptake of AntimiRs alter microRNA-34a levels in 2D and 3D epithelial cell culture by Julie Weidner, Ewa Kolosionek, Reetta Holmila, Elisabeth Ax, Marion Garreau, Felix Gnerlich, Henric Olsson, Werngard Czechtizky, Stefan Vollmer, Anna M. Rydzik

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Recent evolution on synthesis strategies and anti-leishmanial activity of β-carboline derivatives – An update by Karan Kumar Banoth, Faheem, Kondapalli Venkata Gowri ChandraSekhar, Nandikolla Adinarayana, Sankaranarayanan Murugesan

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New Approach to Drug Discovery of a Safe Mitochondrial Uncoupler: OPC-163493 by Takashi Okamoto, Takahiro Shimada, Chiharu Matsumura, Hitomi Minoshima, Takashi Ban, Motohiro Itotani, Toshio Shinohara, Shigekazu Fujita, Satoshi Matsuda, Seiji Sato, Naohide Kanemoto

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Synthesis and Biochemical Evaluation of Lid-Open D-Amino Acid Oxidase Inhibitors by Bence Szilágyi, Csilla Hargitai, Ádám A. Kelemen, Anita Rácz, György G. Ferenczy, Balázs Volk, György M. Keserű

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Assessment of dual inhibitory activity of epifriedelanol isolated from Cayratia trifolia against ovarian cancer by Palanisamy Chella Perumal, Sundaram Sowmya, Devadasan Velmurugan, Thirunavukkarasu Sivaraman, Velliyur Kanniappan Gopalakrishnan

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Bromo-Cyclobutenaminones as New Covalent UDP-<i>N</i>-Acetylglucosamine Enolpyruvyl Transferase (MurA) Inhibitors by David J. Hamilton, Péter Ábrányi-Balogh, Aaron Keeley, László Petri, Martina Hrast, Tímea Imre, Maikel Wijtmans, Stanislav Gobec, Iwan J. P. de Esch, György Miklós Keserű

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PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells by Susanne Prokop, Péter Ábrányi-Balogh, Benjámin Barti, Márton Vámosi, Miklós Zöldi, László Barna, Gabriella M. Urbán, András Dávid Tóth, Barna Dudok, Attila Egyed, Hui Deng, Gian Marco Leggio, László Hunyady, Mario van der Stelt, György M. Keserű, István Katona

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Recent Advances in the Synthesis of Isothiocyanates Using Elemental Sulfur by András Gy. Németh, Péter Ábrányi-Balogh

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Discovery of a Non-Nucleoside SETD2 Methyltransferase Inhibitor against Acute Myeloid Leukemia by Dávid Bajusz, Zsolt Bognár, Jessica Ebner, Florian Grebien, György M. Keserű

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Boronic acid inhibitors of penicillin-binding protein 1b: serine and lysine labelling agents by Levente Kollár, Katarina Grabrijan, Martina Hrast Rambaher, Krištof Bozovičar, Tímea Imre, György G. Ferenczy, Stanislav Gobec, György M. Keserű

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