Applicability of an Experimental Grade of Hydroxypropyl Methylcellulose Acetate Succinate as a Carrier for Formation of Solid Dispersion with Indomethacin by Hiroshi Ueda, Yuya Hirakawa, Hironori Tanaka, Tetsuya Miyano, Katsuji Sugita

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Mechanistic and thermodynamic characterization of oxathiazolones as potent and selective covalent immunoproteasome inhibitors by Levente M. Mihalovits, György G. Ferenczy, György M. Keserű

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Anticonvulsant activity of novel 1-(morpholinomethyl)-3-substituted isatin derivatives by Govindaraj Saravanan, Veerachamy Alagarsamy, Pandurangan Dineshkumar

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DockStream: a docking wrapper to enhance de novo molecular design by Jeff Guo, Jon Paul Janet, Matthias R. Bauer, Eva Nittinger, Kathryn A. Giblin, Kostas Papadopoulos, Alexey Voronov, Atanas Patronov, Ola Engkvist, Christian Margreitter

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Novel UV spectrophotometer methods for quantitative estimation of metronidazole and furazolidone using mixed hydrotropy solubilization by Ruchi Jain, Nilesh Jain, Deepak Kumar Jain, Vijay Kumar Patel, Harish Rajak, Surendra Kumar Jain

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Synthesis, characterization and in vitro antimicrobial activity of some 1-(substitutedbenzylidene)-4-(4-(2-(methyl/phenyl)-4-oxoquinazolin-3(4H)-yl)phenyl)semicarbazide derivatives by Govindaraj Saravanan, Veerachamy Alagarsamy, Chinnasamy Rajaram Prakash

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Embryonic Vascular Toxicity of Calotropis Procera; Evaluation of Early Anti-Vasculogenic Property and Molecular Aspects Using A Chick’s Extra-Embryonic Membrane Model by Hadi Tavakkoli, Amin Derakhshanfar, Javad Moayedi, Ali Poostforoosh Fard, Somayeh Behrouz, Mohammad Amin Piltan, Mohammad Navid Soltani Rad

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Metal-free photocatalytic cross-electrophile coupling enables C1 homologation and alkylation of carboxylic acids with aldehydes by Stefano Bonciolini, Antonio Pulcinella, Matteo Leone, Debora Schiroli, Adrián Luguera Ruiz, Andrea Sorato, Maryne A. J. Dubois, Ranganath Gopalakrishnan, Geraldine Masson, Nicola Della Ca’, Stefano Protti, Maurizio Fagnoni, Eli Zysman-Colman, Magnus Johansson, Timothy Noël

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K-685, a TRPV1 Antagonist, Blocks PKC-Sensitized TRPV1 Activation and Improves the Inflammatory Pain in a Rat Complete Freund’s Adjuvant Model by Yoshiyuki Sugimoto, Yozo Kojima, Atsushi Inayoshi, Kazuaki Inoue, Hiroko Miura-Kusaka, Kiyotoshi Mori, Osamu Saku, Hiroshi Ishida, Eri Atsumi, Yoshisuke Nakasato, Shiro Shirakura, Shin-ichiro Toki, Katsumi Shinoda, Nobuyuki Suzuki

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Spiro[pyrrolidine-3,3′-oxindoles] and Their Indoline Analogues as New 5-HT6 Receptor Chemotypes by Ádám A. Kelemen, Grzegorz Satala, Andrzej J. Bojarski, György M. Keserű

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Semisynthetic teicoplanin derivatives with dual antimicrobial activity against SARS-CoV-2 and multiresistant bacteria by Ilona Bereczki, Vladimir Vimberg, Eszter Lőrincz, Henrietta Papp, Lajos Nagy, Sándor Kéki, Gyula Batta, Ana Mitrović, Janko Kos, Áron Zsigmond, István Hajdú, Zsolt Lőrincz, Dávid Bajusz, László Petri, Jan Hodek, Ferenc Jakab, György M. Keserű, Jan Weber, Lieve Naesens, Pál Herczegh, Anikó Borbás

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Comparative Evaluation of Prosopis cineraria (L.) Druce and Its ZnO Nanoparticles on Scopolamine Induced Amnesia by Ekta Yadav, Deepika Singh, Pankajkumar Yadav, Amita Verma

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Resveratrol: A potential therapeutic natural polyphenol for neurodegenerative diseases associated with mitochondrial dysfunction by Ekta Yadav, Pankajkumar Yadav, Mohd Masih Uzzaman Khan, HariOm Singh, Amita Verma

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Late-stage meta-C–H alkylation of pharmaceuticals to modulate biological properties and expedite molecular optimisation in a single step by Lucas Guillemard, Lutz Ackermann, Magnus J. Johansson

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Improving reproducibility and reusability in the Journal of Cheminformatics by Charles Tapley Hoyt, Barbara Zdrazil, Rajarshi Guha, Nina Jeliazkova, Karina Martinez-Mayorga, Eva Nittinger

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Multiwell Raman plate reader for high-throughput biochemical screening by Hiroyuki Kawagoe, Jun Ando, Miwako Asanuma, Kosuke Dodo, Tetsuya Miyano, Hiroshi Ueda, Mikiko Sodeoka, Katsumasa Fujita

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Relative Strength of Common Directing Groups in Palladium-Catalyzed Aromatic C−H Activation by Anna Tomberg, Michael Éric Muratore, Magnus Jan Johansson, Ina Terstiege, Christian Sköld, Per-Ola Norrby

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Exploring protein hotspots by optimized fragment pharmacophores by Dávid Bajusz, Warren S. Wade, Grzegorz Satała, Andrzej J. Bojarski, Janez Ilaš, Jessica Ebner, Florian Grebien, Henrietta Papp, Ferenc Jakab, Alice Douangamath, Daren Fearon, Frank von Delft, Marion Schuller, Ivan Ahel, Amanda Wakefield, Sándor Vajda, János Gerencsér, Péter Pallai, György M. Keserű

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Design, synthesis, in vitro, and in silico evaluations of kojic acid derivatives linked to amino pyridine moiety as potent tyrosinase inhibitors by Davood Rezapour Niri, Mohammad Hosein Sayahi, Somayeh Behrouz, Ali Moazzam, Fatemeh Rasekh, Nader Tanideh, Cambyz Irajie, Mohammad Seif Nezhad, Bagher Larijani, Aida Iraji, Mohammad Mahdavi

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Biomedical data analyses facilitated by open cheminformatics workflows by Eva Nittinger, Alex Clark, Anna Gaulton, Barbara Zdrazil

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