Laboratory medicine in the era of precision medicine – dream or reality? by Dobreanu Minodora, Oprea Oana Roxana

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Molecular characterization and biomarker identification in colorectal cancer: Toward realization of the precision medicine dream by Goel G

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Targeting abnormal metabolism in Alzheimer's disease: The Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study by Rishi J. Desai, Vijay R. Varma, Tobias Gerhard, Jodi Segal, Mufaddal Mahesri, Kristyn Chin, Edward Nonnenmacher, Avinash Gabbeta, Anup M. Mammen, Sudhir Varma, Daniel B. Horton, Seoyoung C. Kim, Sebastian Schneeweiss, Madhav Thambisetty

“…We describe the rationale and design of the Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study, an innovative multidisciplinary alternative to traditional drug discovery. …”
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Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B by Yu Zhang, Benjamin Schmid, Nanett K. Nikolaisen, Mikkel A. Rasmussen, Blanca I. Aldana, Mikkel Agger, Kirstine Calloe, Tina C. Stummann, Hjalte M. Larsen, Troels T. Nielsen, Jinrong Huang, Fengping Xu, Xin Liu, Lars Bolund, Morten Meyer, Lasse K. Bak, Helle S. Waagepetersen, Yonglun Luo, Jørgen E. Nielsen, Bjørn Holst, Christian Clausen, Poul Hyttel, Kristine K. Freude

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The role of inhaled methoxyflurane in acute pain management by Porter KM, Dayan AD, Dickerson S, Middleton PM

“…Keith M Porter,1 Anthony D Dayan,2 Sara Dickerson,3 Paul M Middleton4,5 1Trauma Department, University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, UK; 2Independent Consultant, London, UK; 3Medical Affairs, Mundipharma International Limited, Cambridge, UK; 4Emergency Medicine Research Unit, Liverpool Hospital, Sydney, NSW, Australia; 5Distributed Research in Emergency and Acute Medicine (DREAM) Collaboration, Sydney, NSW, Australia Abstract: Methoxyflurane is an inhaled analgesic administered via a disposable inhaler which has been used in Australia for over 40 years for the management of pain associated with trauma and for medical procedures in children and adults. …”
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Cost-effectiveness strategies in OSAS management: a short review by D.M. Toraldo, D. Passali, A. Sanna, F. De Nuccio, L. Conte, M. De Benedetto

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Obstructive Sleep Apnea With or Without Excessive Daytime Sleepiness: Clinical and Experimental Data-Driven Phenotyping by Sergio Garbarino, Sergio Garbarino, Egeria Scoditti, Paola Lanteri, Luana Conte, Luana Conte, Nicola Magnavita, Domenico M. Toraldo

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Development and maintenance of a medical education research registry by Jeffrey A. Wilhite, Lisa Altshuler, Sondra Zabar, Colleen Gillespie, Adina Kalet

“…Grossman School of Medicine established the Database for Research on Academic Medicine (DREAM). DREAM is a database of routinely collected, de-identified undergraduate (UME, medical school leading up to the Medical Doctor degree) and graduate medical education (GME, residency also known as post graduate education leading to eligibility for specialty board certification) outcomes data available, through application, to researchers. …”
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Are phosphodiesterase type 5 inhibitors potential therapies for Alzheimer’s Disease and related dementias? by Newby, D

“…This scientific commentary refers to ‘No association between initiation of phosphodiesterase-5 inhibitors and risk of incident Alzheimer’s disease and related dementia: results from the Drug Repurposing for Effective Alzheimer’s Medicines (DREAM) study’ by Desai et al. (https://doi.org/10.1093/braincomms/fcac247) in Brain Communications.…”