Memory cueing during sleep modifies the interpretation of ambiguous scenes in adolescents and adults by Sabine Groch, Dana McMakin, Patrick Guggenbühl, Björn Rasch, Reto Huber, Ines Wilhelm

“…Half of the words were acoustically presented (i.e. cued) during post-learning sleep which is known to benefit memory consolidation by inducing reactivation of learned information. …”
Get full text

Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory by Li Lv, Yunlong Liu, Jianxin Xie, Yan Wu, Jianjian Zhao, Qian Li, Yi Zhong

“…Memory consolidation theory suggests that memory is maintained at a stable strength after formation. …”
Get full text

Chemogenomic analysis reveals key role for lysine acetylation in regulating Arc stability by Jasmin Lalonde, Surya A. Reis, Sudhir Sivakumaran, Carl S. Holland, Hendrik Wesseling, John F. Sauld, Begum Alural, Wen-Ning Zhao, Judith A. Steen, Stephen J. Haggarty

“…The activity-regulated cytoskeleton-associated protein (Arc) has been implicated in synaptic plasticity and memory consolidation. Here the authors show that Arc acetylation regulates its stability and identify small molecules that modulate Arc expression.…”
Get full text

Does sleep protect memories against interference? A failure to replicate. by Carrie Bailes, Mary Caldwell, Erin J Wamsley, Matthew A Tucker

“…In these studies, interference learning was much less detrimental to memory following a night of sleep compared to a day of wakefulness, an indication that sleep supports this important aspect of memory consolidation. In the current replication study, we repeated the protocol of and, additionally, we examined the impact of intrinsic motivation on performance in sleep and wake participants. …”
Get full text

Inhibiting Glutamate Activity during Consolidation Suppresses Age-Related Long-Term Memory Impairment in Drosophila by Motomi Matsuno, Junjiro Horiuchi, Kyoko Ofusa, Tomoko Masuda, Minoru Saitoe

“…Altogether, our results indicate that LTM formation requires glial-dependent inhibition of glutamate signaling during memory consolidation, and aging disrupts this process by inhibiting the Klg-Repo-EAAT1 pathway. : Behavioral Neuroscience; Molecular Neuroscience; Model Organism Subject Areas: Behavioral Neuroscience, Molecular Neuroscience, Model Organism…”
Get full text

Predictive Potential of Circulating Ube2h mRNA as an E2 Ubiquitin-Conjugating Enzyme for Diagnosis or Treatment of Alzheimer’s Disease by Key-Hwan Lim, Jae-Yeol Joo

“…Alzheimer’s disease (AD) is one of the age-related disorders, which are the most common degenerative disorders today, and strongly affects memory consolidation and cognitive function in the brain. …”
Get full text

The hippocampus remains activated over the long term for the retrieval of truly episodic memories. by Caroline Harand, Françoise Bertran, Renaud La Joie, Brigitte Landeau, Florence Mézenge, Béatrice Desgranges, Philippe Peigneux, Francis Eustache, Géraldine Rauchs

“…The role of the hippocampus in declarative memory consolidation is a matter of intense debate. We investigated the neural substrates of memory retrieval for recent and remote information using functional magnetic resonance imaging (fMRI). 18 young, healthy participants learned a series of pictures. …”
Get full text

Hippocmapal Opioid Recptors Probably Mediating the Effects of Peripheal Corticosterone on Consolidation and Retreival of Spatial Memory in Rat by AA. Vafaei, A. Rashidy-Pour, AA. Sajadi

“…Also Nalthroxone (10 and 20 μg/ul/ per side) was injected bilaterally into hippocmapus immediately after training or 60 min before retrieval test.Results: The results indicated that injection of corticostrone immediatly after trainingor 30 min before retention significantly enhanced or impaired consolidation and retrieval memory respectively (p<0.01) and these effects were blocked by injection of naltroxone in to DH (p<0.05) in either cases.Conclusion: The findings suggest that the opioid receptors in hippocampus play an important role in mediating the enhancing or impairing effects of systemic corticosteroneon memory consolidation and retrieval.…”
Get full text

Bi-frontal transcranial alternating current stimulation in the ripple range reduced overnight forgetting by Géza Gergely eAmbrus, Géza Gergely eAmbrus, Alberto ePisoni, Annika ePrimaßin, Zsolt eTuri, Walter ePaulus, Andrea eAntal

“…High frequency oscillations in the hippocampal structures recorded during sleep have been proved to be essential for long-term episodic memory consolidation in both animals and in humans. The aim of this study was to test if transcranial Alternating Current Stimulation (tACS) of the dorsolateral prefrontal cortex (DLPFC) in the hippocampal ripple range, applied bi-frontally during encoding, could modulate declarative memory performance, measured immediately after encoding, and after a night’s sleep. …”
Get full text

The role of nocturnal sleep on the retention, adaptability, and relearning rate of a motor skill by Fernanda Yngrid Martins Sousa, Yasmin de Melo Rocha e Silva, Ana Kariele da Silva Santos, Gisele Carla dos Santos Palma, Renata Louise Ferreira Lemos, Giordano Marcio Gatinho Bonuzzi

“…Abstract Aim: The influence of sleep on the adaptability and relearning rate during learning of complex motor skills is still unknown, limiting the comprehension of the sleep role in motor memory consolidation. Thus, we aimed to investigate the nocturnal sleep influence on retention, adaptability, and relearning rate of the dart-throwing task. …”
Get full text

Ventral tegmental area inactivation suppresses the expression of CA1 long term potentiation in anesthetized rat. by Elham Ghanbarian, Fereshteh Motamedi

“…It can be concluded that VTA activity has no effect on CA1 LTP induction and acquisition of PA task, but involves in the expression of LTP and PA memory consolidation.…”
Get full text

The relationship between brain morphology and polysomnography in healthy good sleepers. by Matthias A Reinhard, Wolfram Regen, Chiara Baglioni, Christoph Nissen, Bernd Feige, Jürgen Hennig, Dieter Riemann, Kai Spiegelhalder

“…The volume of the left postcentral gyrus was positively associated with periodic leg movements during sleep (PLMS).The function of the anterior cingulate cortex as well as EEG beta power during REM sleep have been related to dreaming and sleep-related memory consolidation, which may explain the observed correlation. …”
Get full text

Cofilin overactivation improves hippocampus-dependent short-term memory by Frank Raven, Iris W. Riemersma, Martha F. Olthuis, Ieva Rybakovaite, Elroy L. Meijer, Peter Meerlo, Eddy A. Van der Zee, Robbert Havekes

“…Most information is initially stored as short-term memory, which is then converted to a more stable long-term memory through a process called memory consolidation. At the neuronal level, synaptic plasticity is crucial for memory storage. …”
Get full text

Does Sleep Improve Your Grammar? Preferential Consolidation of Arbitrary Components of New Linguistic Knowledge. by Jelena Mirković, M Gareth Gaskell

“…We examined the role of sleep-related memory consolidation processes in learning new form-meaning mappings. …”
Get full text

A Review of Accelerated Long-Term Forgetting in Epilepsy by Rūta Mameniškienė, Kristijonas Puteikis, Arminas Jasionis, Dalius Jatužis

“…Analysis of recently reported data among patients with temporal lobe epilepsy, transient epileptic amnesia, and generalized and extratemporal epilepsies provided further indication that ALF is likely a disorder of late memory consolidation. The spatial substrate of ALF might be located along the parts of the hippocampal–neocortical network and novel studies reveal the increasingly possible importance of damage in extrahippocampal sites. …”
Get full text

Dreamento: an open-source dream engineering toolbox for sleep EEG wearables by Mahdad Jafarzadeh Esfahani, Amir Hossein Daraie, Paul Zerr, Frederik D. Weber, Martin Dresler

“…Nevertheless, its applications can be extended to other areas of sleep research such as closed-loop auditory stimulation and targeted memory reactivation to enhance memory consolidation during sleep.…”
Get full text

Effect of Letrozole during Pregnancy on Learning and Memory of Offspring Rats by Minoo Mahmoodi, Mozhgan Zeini, Siamak Shahidi

“…ABSTRACT        Background and Objectives: Hippocampus is the main structure involved in spatial learning and memory consolidation. Formation of spatial memory can be strongly influenced by medications, hormones and different substances. …”
Get full text

Meaningful objects avoid attribute amnesia due to incidental long-term memories by Edyta Sasin, Yuri Markov, Daryl Fougnie

“…Abstract Attribute amnesia describes the failure to unexpectedly report the attribute of an attended stimulus, likely reflecting a lack of working memory consolidation. Previous studies have shown that unique meaningful objects are immune to attribute amnesia. …”
Get full text

NREM2 and Sleep Spindles Are Instrumental to the Consolidation of Motor Sequence Memories. by Samuel Laventure, Stuart Fogel, Ovidiu Lungu, Geneviève Albouy, Pénélope Sévigny-Dupont, Catherine Vien, Chadi Sayour, Julie Carrier, Habib Benali, Julien Doyon

“…Although numerous studies have convincingly demonstrated that sleep plays a critical role in motor sequence learning (MSL) consolidation, the specific contribution of the different sleep stages in this type of memory consolidation is still contentious. To probe the role of stage 2 non-REM sleep (NREM2) in this process, we used a conditioning protocol in three different groups of participants who either received an odor during initial training on a motor sequence learning task and were re-exposed to this odor during different sleep stages of the post-training night (i.e., NREM2 sleep [Cond-NREM2], REM sleep [Cond-REM], or were not conditioned during learning but exposed to the odor during NREM2 [NoCond]). …”
Get full text

Exploring clinical applications and long-term effectiveness of benzodiazepines: An integrated perspective on mechanisms, imaging, and personalized medicine by Yiheng Chang, Xueting Xie, Yudan Liu, Meichen Liu, Huimin Zhang

“…Benzodiazepines can facilitate sleep-dependent memory consolidation by promoting spindle wave activity, but they can also lead to memory deficits in older individuals due to reduced slow-wave sleep. …”
Get full text