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861
The role of emotional processing and regulation in the link between insomnia and depression
Published 2024“…Findings suggest that overnight memory consolidation and emotional reactivity for negative stimuli are not affected in insomnia. …”
Thesis -
862
Distinct roles of dopamine and subthalamic nucleus in learning and probabilistic decision making.
Published 2012“…Thus, we demonstrate distinct mechanisms for two important facets of human decision making: first, a role for dopamine in memory consolidation, and second, the critical importance of the subthalamic nucleus in successful decision making when multiple pieces of information must be combined.…”
Journal article -
863
Perisomatic-targeting interneurons control the initiation of hippocampal population bursts
Published 2009“…It is thought that this activity, which occurs during rest and sleep, is involved in memory consolidation. The cellular mechanisms underlying the initiation of these replay events are not well understood. …”
Thesis -
864
Functional differentiation along the dorso-ventral axis of the hippocampus
Published 2013“…During exploration, theta oscillations (4-12 Hz) are prominent in the hippocampus, whereas during sleep and rest irregular sharp wave/ripple (SWR) events occur spontaneously in the hippocampus and may support memory consolidation. To date, the ventral sub-region of the rodents hippocampus, has received less attention relative to the more accessible dorsal part. …”
Thesis -
865
Reactivation and reinstatement of hippocampal assemblies
Published 2017“…Specifically, I performed a causal test of the long-standing hypothesis that the offline reactivation of new, memory-representing cell assemblies supports memory consolidation by stabilizing those assemblies and increasing the likelihood of their later reinstatement—and therefore presumably of memory recall.…”
Thesis -
866
Lack of drug-induced post-retrieval amnesia for auditory fear memories in rats
Published 2021-01-01“…Abstract Background Long-term memory formation is generally assumed to involve the permanent storage of recently acquired memories, making them relatively insensitive to disruption, a process referred to as memory consolidation. However, when retrieved under specific circumstances, consolidated fear memories are thought to return to a labile state, thereby opening a window for modification (e.g., attenuation) of the memory. …”
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867
The thalamic reuniens is associated with consolidation of non-spatial memory too
Published 2023-08-01“…This anatomical relationship positions the Re as an ideal candidate to facilitate memory consolidation. However, there is no evidence that this role extends beyond spatial memory and contextual fear memory, which are both strongly associated with hippocampal function. …”
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868
Non-REM sleep in major depressive disorder
Published 2022-01-01“…Overnight procedural memory consolidation was impaired in medicated patients and associated with lower sleep spindle density. …”
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869
Sleep and Epilepsy Link by Plasticity
Published 2020-08-01“…MTLE links to the memory-system, where epileptic transformation results in a switch of normal sharp wave-ripples to epileptic spikes and pathological high frequency oscillations, compromising sleep-related memory consolidation. Absence epilepsy (AE) and juvenile myoclonic epilepsy (JME) belong to the corticothalamic system. …”
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Article -
870
The Default Mode Network Supports Episodic Memory in Cognitively Unimpaired Elderly Individuals: Different Contributions to Immediate Recall and Delayed Recall
Published 2018-01-01“…These results suggest that the DMN plays different roles in memory retrieval across different retention intervals, and connections between the DMN regions contribute to memory consolidation of past events in healthy older people.…”
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871
Motor Sequence Learning Is Associated With Hippocampal Subfield Volume in Humans With Medial Temporal Lobe Epilepsy
Published 2018-09-01“…Objectives: Medial temporal lobe epilepsy (mTLE) is characterized by decreased hippocampal volume, which results in motor memory consolidation impairments. However, the extent to which motor memory acquisition are affected in humans with mTLE remains poorly understood. …”
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872
Ill-Defined Problem Solving Does Not Benefit From Daytime Napping
Published 2020-04-01“…However, while sleep-related memory consolidation seems to be well-grounded, with regard to the impact of sleep on problem solving, existing research yields mixed and rather inconclusive results. …”
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Article -
873
Childhood adversity and acute stress vulnerability at adulthood: The mediating role of sleep
Published 2023-03-01“…Third, inefficient sleep pre and post exposure to acute stress was shown to increase the likelihood for maladaptive outcome, potently by impairing critical processes that occur during sleep as arousal regulation and memory consolidation. Objectives To date, very few studies integrated these independent lines of research. …”
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874
Acute Physiology and Neurologic Outcomes after Brain Injury in SCOP/PHLPP1 KO Mice
Published 2018-05-01“…PHLPP1) regulates long-term memory consolidation in the brain. Using a mouse model of controlled cortical impact (CCI) we tested if (1) brain tissue levels of SCOP/PHLPP1 increase after a traumatic brain injury (TBI), and (2) if SCOP/PHLPP1 gene knockout (KO) mice have improved (or worse) neurologic outcomes. …”
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875
Sleep Facilitates Problem Solving With No Additional Gain Through Targeted Memory Reactivation
Published 2021-03-01“…These changes may generate new knowledge such as gaining insight into solutions for problem solving. targeted memory reactivation (TMR) uses learning-associated cues, such as sounds or odors, which have been shown to improve memory consolidation when re-applied during sleep. Here we tested whether TMR during slow wave sleep (SWS) and/or rapid eye movement (REM) sleep increases problem solving. …”
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876
Tonically Active α2 Subunit-Containing Glycine Receptors Regulate the Excitability of Striatal Medium Spiny Neurons
Published 2018-01-01“…Mice lacking GlyR α2 showed impaired motor memory consolidation without any changes in the initial motor performance. …”
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877
Cholecystokinin enhances visceral pain-related affective memory via vagal afferent pathway in rats
Published 2012-06-01“…</p> <p>Conclusion</p> <p>CCK activating vagal afferent C fibers enhances memory consolidation and retention involved in long-term visceral negative affective state. …”
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878
NREM sleep oscillations and brain plasticity in aging
Published 2012-12-01“…We propose that age-related reduction in sleep-dependent memory consolidation may be due in part to changes in NREM sleep oscillations.…”
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Article -
879
Generalization and discrimination of inhibitory avoidance differentially engage anterior and posterior retrosplenial subregions
Published 2024-01-01“…Further, PNNs did not reduce in the RSC in animals who showed a generalized avoidance behavior, in line with their hypothesized role in memory consolidation.DiscussionThese findings suggest that there is differential engagement of retrosplenial subregions along the rostrocaudal axis to generalization and discrimination.…”
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880
Improving the detection of sleep slow oscillations in electroencephalographic data
Published 2024-02-01“…The machine learning and deep learning algorithms showed higher accuracy (best: 99.20%) while maintaining a low prediction time.ConclusionsAccurate detection of SO events is important for investigating their role in memory consolidation. In this context, our tool and proposed methods can provide significant help in identifying these events.…”
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