A real-world comparison of the clinical and economic utility of OVA1 and CA125 in assessing ovarian tumor malignancy risk by Gerard P Reilly, David A Gregory, Dennis J Scotti, Samuel Lederman, Wade A Neiman, Steven Sussman, Lisa M Bean, Mercedes M Ekono

“…Payer allowed amounts from Merative MarketScan Research Databases were used to estimate 12-month episode-of-care costs per patient, including surgery and other interventions. …”

Anti-migraine medications safety during pregnancy in the US by A. Bérard, A. Bérard, A. Bérard, S. Strom, D. Albrecht, S. Kori

“…BackgroundSpecific antimigraine medications (dihydroergotamine (DHE), triptans) have been associated with adverse pregnancy outcomes in individual studies but lack of consensus remains.ObjectivesQuantify the risk of prematurity, low birth weight (LBW), major congenital malformations (MCM), and spontaneous abortions (SA) associated with gestational use of DHE or triptans in a privately insured cohort of pregnant women in the US.MethodsWe conducted a cohort study within the US Merative MarketScan Research Database (2011–2021), composed of a nationally representative sample of patients with employer-provided health insurance. …”
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Economic burden of cardiorespiratory hospitalizations associated with respiratory syncytial virus among United States adults in 2017–2019 by Deesha A Patel, Zachary A Marcum, Aisara Chansakul, Astra Toyip, Katherine Nerney, Catherine A Panozzo, Samantha St Laurent, Darshan Mehta, Parinaz Ghaswalla

“…To assist vaccine policy decision-makers and payers, we estimated the annual economic burden of RSV-associated cardiorespiratory hospitalizations among insured US adults aged ≥18 y in the Merative MarketScan claims database from September through August of 2017–2018 and 2018–2019. …”
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Treatment setting and buprenorphine discontinuation: an analysis of multi-state insurance claims by Kevin Y. Xu, Alex K. Gertner, Shelly F. Greenfield, Arthur Robin Williams, Richard A. Grucza

“…Methods In this observational, retrospective cohort study using the Merative MarketScan databases (2006–2016), we analyzed buprenorphine retention in 58,200 US adults with OUD. …”
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Racial and ethnic differences in patterns of use and discontinuation of long-acting injectable antipsychotics using Medicaid claims data by Caballero Joshua PharmD, BCPP, FCCP, Xu Jianing MS, Hall Daniel B. PhD, Chen Xianyan PhD, Young Henry N. PhD

“…Methods International Classification of Diseases, 10th edition (ICD-10) codes were used to identify patients with schizophrenia and related disorders (18-64 years) who received an LAI antipsychotic between 2016 and 2020 using Merative Multi-State Medicaid databases. Using National Drug Code numbers for LAI antipsychotics, pharmacy claims were identified and data analyzed. …”
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Work loss among privately insured employees with overweight and obesity in the United States by Shraddha Shinde, Anh Thu Tran, Michelle Jerry, Clare J. Lee

“…Methods This retrospective cohort study used the MerativeTM MarketScan® Health and Productivity Management Database to identify adult employees with ≥1 diagnosis code reporting a body mass index (BMI) between 1/1/2015‐12/31/2019. …”
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One-year healthcare costs after robotic-assisted and laparoscopic partial and radical nephrectomy: a cohort study by Kennedy E. Okhawere, Gediwon Milky, Shirin Razdan, I-Fan Shih, Yanli Li, Laura Zuluaga, Ketan K. Badani

“…Patients and methods This cohort study used the MerativeTM MarketScan® Databases between 2013 and 2020. …”
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Prescription amphetamines in people with opioid use disorder and co-occurring psychostimulant use disorder initiating buprenorphine: an analysis of treatment retention and overdose... by Frances R Levin, Richard A Grucza, Vitor Tardelli, Kevin Y Xu, Adam Bisaga, Thiago M Fidalgo

“…There remains concern about the safety and efficacy of prescription amphetamines (PAs) and their impact on effectiveness of opioid use disorder (OUD) treatment with buprenorphine.Objectives To assess the effect of PAs on OUD buprenorphine treatment retention and/or SUD-related emergency admission or drug-related poisonings.Methods We used a retrospective cohort design with a secondary analysis of data from Merative MarketScan Commercial and Multi-State Medicaid Databases from 1 January 2006 to 31 December 2016. …”
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Clinical effectiveness of paliperidone palmitate 3‐monthly and 1‐monthly as monotherapy in patients with schizophrenia: A retrospective cohort study based on the Medicaid claims da... by Chih‐Lin Chiang, Madoka Chinen, Mehmet Daskiran, Akihide Wakamatsu, Ibrahim Turkoz

“…Methods Retrospective analyses were conducted using RWD from Merative™ MarketScan® Multi‐State Medicaid (MDCD) claims database (June 2015–December 2022). …”
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Opioid and non-opioid analgesic regimens after fracture and risk of serious opioid-related events by Ashley A Leech, Andrew D Wiese, Kyle Hart, Andrew J Medvecz, Avi Vaidya, Stacie Dusetzina

“…We compared the risk of SOREs among hospitalized patients with long bone fracture discharged with filled opioid prescriptions, with and without non-opioid analgesics.Design We identified a retrospective cohort of analgesic-naïve adult patients with a long bone fracture hospitalization using the Merative MarketScan Commercial Database (2013–2020). …”
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Prevalence of complications and comorbidities associated with obesity: a health insurance claims analysis by Jay P. Bae, David R. Nelson, Kristina S. Boye, Kieren J. Mather

“…Methods This cross-sectional study analyzed individuals from all four regions (Midwest, Northeast, South, and West) of the US who had continuous insurance coverage from 2018 to 2020, using a large health insurance claims database (Merative™ MarketScan®). Identification of disorders relied on ICD-10 diagnosis code in patient claims and their prevalence was calculated. …”
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Real-world Impact of Fremanezumab on Migraine-Related Health Care Resource Utilization in Patients with Comorbidities, Acute Medication Overuse, and/or Unsatisfactory Prior Migrain... by Dawn C. Buse, Lynda J. Krasenbaum, Michael J. Seminerio, Elizabeth R. Packnett, Karen Carr, Mario Ortega, Maurice T. Driessen

“…Methods Data for this US, retrospective claims analysis were obtained from the Merative® MarketScan® Commercial and supplemental databases. …”
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Apremilast Adherence and Persistence in Patients with Psoriasis and Psoriatic Arthritis in the Telehealth Setting Versus the In-person Setting During the COVID-19 Pandemic by Ashis K. Das, Eunice Chang, Caleb Paydar, Michael S. Broder, Kate K. Orroth, Myriam Cordey

“…Methods We estimated adherence and persistence among US patients in the Merative© MarketScan© Commercial and Supplemental Medicare Databases who newly initiated apremilast between April and June 2020, categorized by the type of visit (telehealth or in-person) when apremilast was first prescribed. …”
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Ixekizumab Treatment Patterns and Health Care Resource Utilization Among Patients with Axial Spondyloarthritis: A Retrospective United States Claims Database Study by Abhijeet Danve, Aisha Vadhariya, Jeffrey Lisse, Arjun Cholayil, Neha Bansal, Natalia Bello, Catherine Bakewell

“…We evaluated ixekizumab treatment patterns and health care resource utilization (HCRU) in patients with axSpA using United States Merative L.P. MarketScan® Claims Databases. Methods This retrospective cohort study included adults with axSpA who initiated ixekizumab during the index period (September 2019–December 2021). …”
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Assessing the Health Economic Outcomes from Commercially Insured Relapsing Multiple Sclerosis Patients Who Switched from Other Disease-Modifying Therapies to Teriflunomide, in the... by Araujo L, Kyatham S, Bzdek KG, Higuchi K, Greene N

“…Lita Araujo,1 Srikanth Kyatham,2 Kristen G Bzdek,1 Keiko Higuchi,1 Nupur Greene1 1Neurology and Immunology, Sanofi, Cambridge, MA, USA; 2Axtria Inc, Berkeley Heights, NJ, USACorrespondence: Lita Araujo, Neurology and Immunology, Sanofi, 450 Water Street, Cambridge, MA, 02141, USA, Tel +1 617 937 9928, Email Lita.Araujo@sanofi.comObjective: Assess patient characteristics, healthcare resource utilization (HCRU), and relapses in patients with multiple sclerosis (MS) who switched to teriflunomide from other disease-modifying therapies (DMTs).Methods: Retrospective study of US Merative™ MarketScan® claims database (Jan 1, 2012–July 31, 2020,) including HIPAA-compliant, deidentified data. …”
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Performance of a Web-Based Reference Database With Natural Language Searching Capabilities: Usability Evaluation of DynaMed and Micromedex With Watson by Angela Rui, Pamela M Garabedian, Marlika Marceau, Ania Syrowatka, Lynn A Volk, Heba H Edrees, Diane L Seger, Mary G Amato, Jacob Cambre, Sevan Dulgarian, Lisa P Newmark, Karen C Nanji, Petra Schultz, Gretchen Purcell Jackson, Ronen Rozenblum, David W Bates

“…EBSCO partnered with IBM Watson Health, now known as Merative, to develop the combined tool as a resource for clinicians. …”
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Azithromycin Exposure in a 10-Day Window of Myocardial Infarction and Short- and Long-Term Outcomes by Amanda Gusovsky, PhD, MPH, Emily Slade, PhD, Jasmine M. Forrest, PharmD, Darren Henderson, BS, Ahmed Abdel-Latif, MD, PhD, Vincent J. Venditto, PhD, Chris Delcher, PhD, David J. Feola, PhD, PharmD

“…Methods: This was a retrospective cohort study using Merative MarketScan databases examining adult inpatients admitted with MI from January 1, 2010 to December 31, 2017. …”
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Risk factors and healthcare costs associated with long bone fracture non-union: a retrospective US claims database analysis by Mari F. Vanderkarr, Jill W. Ruppenkamp, Mollie Vanderkarr, Chantal E. Holy, Michael Blauth

“…Our study was designed to provide a current understanding of non-union risks and costs, from the payers' perspective. Methods The Merative™ MarketScan® Commercial Claims and Encounters database was used. …”
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Characterising incident opioid use among incident users of prescription sedative hypnotics: A national cohort study by Hui Zhao, Harshil Patel, James Douglas Thornton, Eric Schaefer, Chan Shen, Douglas Leslie, Tyler Varisco, Mina Shrestha, Matthew Wanat, Randa Al Saadi

“…Objective To evaluate co-prescribing of sedatives hypnotics and opioids.Design Retrospective study evaluating the association of patient characteristics and comorbidities with coprescribing.Setting and participants Using the national Merative MarketScan Database between 2005 and 2018, we identified patients who received an incident sedative prescription with or without subsequent, incident opioid prescriptions within a year of the sedative prescription in the USA.Outcome measures Coprescription of sedative-hypnotics and opioids.Results A total of 2 632 622 patients (mean (SD) age, 43.2 (12.34) years; 1 297 356 (62.5%) female) received incident prescriptions for sedatives over the course of the study period. …”
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Long-Term Reductions in Opioid Medication Use After Spinal Stimulation: A Claims Analysis Among Commercially-Insured Population by Yong RJ, Tran OV, McGovern AM, Patil PG, Gilligan CJ

“…This study sought to evaluate the effect of SCS on longer term opioid and non-opioid pain medication usage among patients over ≥ 3 years of follow-up.Patients and Methods: Claims analysis was conducted using the Merative™ MarketScan® Commercial Database. Patients aged ≥ 18 who initiated SCS between 1/1/2010 and 3/31/2021 with ≥ 1 year of baseline data and ≥ 3 years of follow-up data were included. …”
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