The Michael J. Fox Foundation's quest for a cure for Parkinson's disease: an interview with Nicole Polinski by Nicole K. Polinski

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The Michael J. Fox Foundation’s Strategies for Accelerating Translation of LRRK2 into Therapies for Parkinson Disease by Shalini Padmanabhan, Brian K. Fiske, Marco A.S. Baptista

“…Since 2005, The Michael J. Fox Foundation for Parkinson’s Research (MJFF) has invested significant funding and non-funding effort to accelerate research and drug development activity around the Parkinson disease (PD)-associated protein LRRK2. …”
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Terminology and Language Used in Indigenous-Specific Gender and Sexuality Diversity Studies: A Systematic Review by Michael J. Fox, Haorui Wu

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MRI-based machine learning radiomics can predict HER2 expression level and pathologic response after neoadjuvant therapy in HER2 overexpressing breast cancer by Almir G.V. Bitencourt, Peter Gibbs, Carolina Rossi Saccarelli, Isaac Daimiel, Roberto Lo Gullo, Michael J. Fox, Sunitha Thakur, Katja Pinker, Elizabeth A. Morris, Monica Morrow, Maxine S. Jochelson

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The GBA1 D409V mutation exacerbates synuclein pathology to differing extents in two alpha-synuclein models by Nicole K. Polinski, Terina N. Martinez, Sylvie Ramboz, Michael Sasner, Mark Herberth, Robert Switzer, Syed O. Ahmad, Lee J. Pelligrino, Sean W. Clark, Jacob N. Marcus, Sean M. Smith, Kuldip D. Dave, Mark A. Frasier

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Automated Quality Control for Sensor Based Symptom Measurement Performed Outside the Lab by Badawy, Reham, Raykov, Yordan P., Evers, Luc J. W., Bloem, Bastiaan R., Faber, Marjan J., Zhan, Andong, Claes, Kasper, Raykov, Yordan, Evers, Luc, Bloem, Bastiaan, Faber, Marjan, Little, Max

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The Experience of OFF Periods in Parkinson’s Disease: Descriptions, Triggers, and Alleviating Factors by Sneha Mantri, Madeline Lepore, Briana Edison, Margaret Daeschler, Catherine M. Kopil, Connie Marras, Lana M. Chahine

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Deep Learning for Daily Monitoring of Parkinson’s Disease Outside the Clinic Using Wearable Sensors by Roozbeh Atri, Kevin Urban, Barbara Marebwa, Tanya Simuni, Caroline Tanner, Andrew Siderowf, Mark Frasier, Magali Haas, Lee Lancashire

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4319 Team Science in Parkinson’s Research: Connecting Clinicians and Computational Teams by Luba Smolensky

“…All author and non-author contributors are grant recipients from The Michael J. Fox Foundation.…”
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LRRK2 and GBA1 variant carriers have higher urinary bis(monacylglycerol) phosphate concentrations in PPMI cohorts by Kalpana M. Merchant, Tanya Simuni, Janel Fedler, Chelsea Caspell-Garcia, Michael Brumm, Kelly N. H. Nudelman, Elizabeth Tengstrandt, Frank Hsieh, Roy N. Alcalay, Christopher Coffey, Lana Chahine, Tatiana Foroud, Andrew Singleton, Daniel Weintraub, Samantha Hutten, Todd Sherer, Brit Mollenhauer, Andrew Siderowf, Caroline Tanner, Ken Marek, the Parkinson’s Progression Markers Initiative

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Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2) by Clodagh Towns, Madeleine Richer, Simona Jasaityte, Eleanor J. Stafford, Julie Joubert, Tarek Antar, Alejandro Martinez-Carrasco, Mary B. Makarious, Bradford Casey, Dan Vitale, Kristin Levine, Hampton Leonard, Caroline B. Pantazis, Laurel A. Screven, Dena G. Hernandez, Claire E. Wegel, Justin Solle, Mike A. Nalls, Cornelis Blauwendraat, Andrew B. Singleton, Manuela M. X. Tan, Hirotaka Iwaki, Huw R. Morris, the Global Parkinson’s Genetics Program (GP2)

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Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2) by Towns, Clodagh, Richer, Madeleine, Jasaityte, Simona, Stafford, Eleanor J., Joubert, Julie, Antar, Tarek, Martinez-Carrasco, Alejandro, Makarious, Mary B., Casey, Bradford, Vitale, Dan, Levine, Kristin, Leonard, Hampton, Pantazis, Caroline B., Screven, Laurel A., Hernandez, Dena G., Wegel, Claire E., Solle, Justin, Nalls, Mike A., Blauwendraat, Cornelis, Singleton, Andrew B., Tan, Manuela M. X., Iwaki, Hirotaka, Morris, Huw R., Foo, Jia Nee

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Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases by Martin Steger, Francesca Tonelli, Genta Ito, Paul Davies, Matthias Trost, Melanie Vetter, Stefanie Wachter, Esben Lorentzen, Graham Duddy, Stephen Wilson, Marco AS Baptista, Brian K Fiske, Matthew J Fell, John A Morrow, Alastair D Reith, Dario R Alessi, Matthias Mann

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Collaboration and knowledge integration for successful brain therapeutics – lessons learned from the pandemic by Maria Isabel Loza, Julija Hmeljak, Chas Bountra, James E. Audia, Sohini Chowdhury, Shannon Weiman, Kalpana Merchant, Maria-Jesus Blanco

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A proteogenomic view of Parkinson’s disease causality and heterogeneity by Sergio Kaiser, Luqing Zhang, Brit Mollenhauer, Jaison Jacob, Simonne Longerich, Jorge Del-Aguila, Jacob Marcus, Neha Raghavan, David Stone, Olumide Fagboyegun, Douglas Galasko, Mohammed Dakna, Bilada Bilican, Mary Dovlatyan, Anna Kostikova, Jingyao Li, Brant Peterson, Michael Rotte, Vinicius Sanz, Tatiana Foroud, Samantha J. Hutten, Mark Frasier, Hirotaka Iwaki, Andrew Singleton, Ken Marek, Karen Crawford, Fiona Elwood, Mirko Messa, Pablo Serrano-Fernandez

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Extracellular Vesicles as Biomarkers for Parkinson’s Disease: How Far from Clinical Translation? by Alice Gualerzi, Silvia Picciolini, Marzia Bedoni, Franca Rosa Guerini, Mario Clerici, Cristina Agliardi

“…The disease brings in also a huge annual economic burden, recently estimated by the Michael J Fox Foundation for Parkinson’s Research to be USD 52 billion in the United States alone. …”
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Mercury and Parkinson’s Disease: Promising Leads, but Research Is Needed by E. Fuller Torrey, Wendy Simmons

“…A search of Parkinsonian research studies currently funded by the US National Institutes of Health, Parkinson’s Foundation, and the Michael J Fox Foundation yielded no studies on mercury. …”
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Prediction of dyskinesia in Parkinson’s disease patients using machine learning algorithms by Denisson Augusto Bastos Leal, Carla Michele Vieira Dias, Rodrigo Pereira Ramos, Ivani Brys

“…Applying machine learning techniques on the data extracted from the Parkinson’s Progression Marker Initiative (PPMI, Michael J. Fox Foundation), this study was aimed to identify PD patients who are at high risk of developing dyskinesias. …”
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Perspective on the current state of the LRRK2 field by Jean-Marc Taymans, Matt Fell, Tim Greenamyre, Warren D. Hirst, Adamantios Mamais, Shalini Padmanabhan, Inga Peter, Hardy Rideout, Avner Thaler

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Incidence of Parkinson disease in North America by A. W. Willis, E. Roberts, J. C. Beck, B. Fiske, W. Ross, R. Savica, S. K. Van Den Eeden, C. M. Tanner, C. Marras, on behalf of the Parkinson’s Foundation P4 Group

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