The Effects and Mechanisms of PBM Therapy in Accelerating Orthodontic Tooth Movement by Xinyuan Wang, Qian Liu, Jinfeng Peng, Wencheng Song, Jiajia Zhao, Lili Chen

“…Simultaneously, based on orthodontic mechanisms and present findings, the mechanisms of acceleration of orthodontic tooth movement (OTM) caused by PBM therapy were explored in relation to four aspects, including blood vessels, inflammatory response, collagen and fibers, and mineralized tissues. Also, the cooperative effects and clinical translation of PBM therapy in orthodontics have been explored in a growing numbers of studies. …”
Get full text

Disrupted Protein Expression and Altered Proteolytic Events in Hypophosphatemic Dentin Can Be Rescued by Dentin Matrix Protein 1 by Elizabeth Guirado, Yinghua Chen, Ryan D. Ross, Youbin Zhang, Catherine Chaussain, Catherine Chaussain, Anne George

“…Dentin, one of the four mineralized tissues of the craniofacial complex, forms sequentially from the deposition of an organic matrix to the nucleation of an inorganic phase within the matrix scaffold. …”
Get full text

The roles of odontoblasts in dental pulp innate immunity by Hiromichi Yumoto, Kouji Hirao, Yuki Hosokawa, Hitomi Kuramoto, Daisuke Takegawa, Tadashi Nakanishi, Takashi Matsuo

“…Summary: Odontoblasts located in the outermost layer of dental pulp form a natural barrier between mineralized tissues, dentin, and soft tissues, dental pulp, of the vital tooth, and they first recognize caries-related pathogens and sense external irritations. …”
Get full text

Mesenchymal Stromal Cells Derived from Dental Tissues: Immunomodulatory Properties and Clinical Potential by Luis Ignacio Poblano-Pérez, Marta Elena Castro-Manrreza, Patricia González-Alva, Guadalupe R. Fajardo-Orduña, Juan José Montesinos

“…Interestingly, D-MSCs are the most suitable source for regenerating mineralized tissues in the oral region. Furthermore, the clinical potential of D-MSCs is supported due to their adequate capacity for proliferation, migration, and differentiation. …”
Get full text

Col11a1 Regulates Bone Microarchitecture during Embryonic Development by Anthony Hafez, Ryan Squires, Amber Pedracini, Alark Joshi, Robert E. Seegmiller, Julia Thom Oxford

“…The observed changes to mineralized tissues further define the function of Col11a1.…”
Get full text

rhBMP-2 Pre-Treated Human Periodontal Ligament Stem Cell Sheets Regenerate a Mineralized Layer Mimicking Dental Cementum by Joo-Young Park, Chan Ho Park, TacGhee Yi, Si-na Kim, Takanori Iwata, Jeong-Ho Yun

“…Therefore, the rhBMP-2-hPDLSC sheet technique could be an effective strategy for the synchronized regeneration of two different tissues: mineralized tissue and fibrous tissues in periodontal complexes.…”
Get full text

Expression of secretory calcium-binding phosphoprotein (scpp) genes in medaka during the formation and replacement of pharyngeal teeth by Tsuyoshi Morita, Shin Matsumoto, Otto Baba

“…The secretory calcium-binding phosphoprotein (scpp) gene cluster is involved in the formation of mineralized tissues, such as dental and bone tissues, and the genes encoding multiple SCPPs are conserved in fish, amphibians, reptiles, and mammals. …”
Get full text

The Role of GH/IGF Axis in Dento-Alveolar Complex from Development to Aging and Therapeutics: A Narrative Review by Kouassi Armel Koffi, Sophie Doublier, Jean-Marc Ricort, Sylvie Babajko, Ali Nassif, Juliane Isaac

“…Beyond its key role in bone physiology, the GH/IGF axis has also major pleiotropic endocrine and autocrine/paracrine effects on mineralized tissues throughout life. This article aims to review the literature on GH, IGFs, IGF binding proteins, and their respective receptors in dental tissues, both epithelium (enamel) and mesenchyme (dentin, pulp, and tooth-supporting periodontium). …”
Get full text

Osteomodulin positively regulates osteogenesis through interaction with BMP2 by Wenzhen Lin, Xiaohan Zhu, Li Gao, Mengying Mao, Daming Gao, Zhengwei Huang

“…Abstract Osteomodulin (OMD), a member of the small leucine-rich proteoglycan family, distributes in mineralized tissues and is positively regulated by bone morphogenetic protein 2 (BMP2). …”
Get full text

The Role of Intrinsically Disordered Proteins in Liquid–Liquid Phase Separation during Calcium Carbonate Biomineralization by Aneta Tarczewska, Klaudia Bielak, Anna Zoglowek, Katarzyna Sołtys, Piotr Dobryszycki, Andrzej Ożyhar, Mirosława Różycka

“…Some animal organs contain mineralized tissues. These so-called hard tissues are mostly deposits of calcium salts, usually in the form of calcium phosphate or calcium carbonate. …”
Get full text

Immediately loaded blade implants. a histological and histomorphometrical evaluation after a long loading period. a retrospective 20 years analysis (1989-2009) by Giovanna Iezzi, Antonio Scarano, Vittoria Perrotti, Domenico Tripodi, Adriano Piattelli

“…Aim: Although the presence of mineralized tissues at the interface with blade implants has been reported, the view that blade implants cannot integrate still persists. …”
Get full text

Bone repair induced by different bone graft substitutes in critical-sized defects in rat calvaria by Mauricio Andrés Tinajero ARONI, Paulo Firmino da COSTA NETO, Guilherme José Pimentel Lopes de OLIVEIRA, Rosemary Adriana Chiérici MARCANTONIO, Elcio MARCANTONIO JUNIOR

“…A microtomographic analysis was performed to evaluate the remaining defect linear length (DLL) of the CSD and the volume of the mineralized tissues (MT) within the CSD at 3, 7, 15 and 30 days after the surgical procedure. …”
Get full text

Bioactive potential of Bio-C Temp demonstrated by systemic mineralization markers and immunoexpression of bone proteins in the rat connective tissue by Camila Soares Lopes, Mateus Machado Delfino, Mário Tanomaru-Filho, Estela Sasso-Cerri, Juliane Maria Guerreiro-Tanomaru, Paulo Sérgio Cerri

“…Bio-C Temp (BIO; Angelus, Brazil), a ready-to-use bioceramic intracanal medication, was designed to stimulate the mineralized tissues formation. Here, we investigated the bioactive potential of BIO in comparison to the CAL in the rat subcutaneous. …”
Get full text

Dynamic expression of IGFBP3 modulate dual actions of mineralization micro-environment during tooth development via Wnt/beta-catenin signaling pathway by MengDan Zhang, Junming Zheng, Siyuan Wu, Hailing Chen, Lusai Xiang

“…Abstract Background Tooth development, as one of the major mineralized tissues in the body, require fine-tuning of mineralization micro-environment. …”
Get full text

Compositional Analysis of the Dental Biomimetic Hybrid Nanomaterials Based on Bioinspired Nonstoichiometric Hydroxyapatite with Small Deviations in the Carbonate Incorporation by Pavel Seredin, Dmitry Goloshchapov, Nikita Buylov, Vladimir Kashkarov, Anna Emelyanova, Konstantin Eremeev, Yuri Ippolitov

“…The results of our work can inspire researchers to study the processes of induced biomineralization in mineralized tissues of the human body, using non-destructive methods of control with simultaneous analysis of chemical bonding, as well as determining the role of impurity atoms in the functions exhibited by biotissue.…”
Get full text

Optimal Recovery of Valuable Biomaterials, Chondroitin Sulfate and Bioapatites, from Central Skeleton Wastes of Blue Shark by José Antonio Vázquez, Javier Fraguas, Pío González, Julia Serra, Jesus Valcarcel

“…Crude bioapatites were purified by pyrolysis and FT-Raman and XRD techniques confirm the presence of hydroxyapatite [Ca₅(PO₄)₃(OH)], with a molar mass of 502.3 g/mol, embedded in the organic matrix of the skeleton. The mineralized tissues of blue shark are promising marine sources for the extraction of high value biomaterials with clinical application in bone and tissue regeneration and are still completely unexplored.…”
Get full text

The skeletal proteome of the sea star Patiria miniata and evolution of biomineralization in echinoderms by Rachel L. Flores, Brian T. Livingston

“…In echinoderms, proteomic analysis of the skeletal proteomes of mineralized tissues of the sea urchin Strongylocentrotus purpuratus prominently featured spicule matrix proteins with repetitive sequences linked to a C-type lectin domain. …”
Get full text

Inflammatory Response Mechanisms of the Dentine–Pulp Complex and the Periapical Tissues by Kerstin M. Galler, Manuel Weber, Yüksel Korkmaz, Matthias Widbiller, Markus Feuerer

“…These highly specialized cells not only form mineralized tissue but exert important functions as barrier cells. …”
Get full text

Evaluation of Feline Permanent Canine Tooth Mineral Density Using Micro-Computed Tomography by Graça Silva, Pedro S. Babo, Jorge Azevedo, Manuela E. Gomes, Carlos Viegas, João F. Requicha

“…The tooth is made up of three mineralized tissues, enamel, dentin, and cementum, which surround a non-mineralized tissue called the dental pulp. …”
Get full text

Mapping the Inorganic and Proteomic Differences among Different Types of Human Teeth: A Preliminary Compositional Insight by Vaibhav Sharma, Simran Rastogi, Kaushal Kumar Bhati, Alagiri Srinivasan, Ajoy Roychoudhury, Fredrik Nikolajeff, Saroj Kumar

“…In recent years, studies on mineralized tissues are becoming increasingly popular not only due to the diverse mechanophysical properties of such materials but also because of the growing need to understand the intricate mechanism involved in their assembly and formation. …”
Get full text