Showing 1 - 20 results of 3,555 for search '"Mitogen-activated protein kinase"', query time: 0.24s Refine Results
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    Targeting the RAS pathway by mitogen-activated protein kinase inhibitors by Michael Kiessling, Gerhard Rogler

    Published 2015-12-01
    “…Now data show that neuroblastoma RAS (NRAS) and even Harvey RAS (HRAS) mutations could be predictive markers for treatment with mitogen-activated protein kinase (MEK) inhibitors. This review discusses recent preclinical and clinical studies of MEK inhibitors in BRAF and RAS mutant cancer. …”
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    Scaffolding of Mitogen-Activated Protein Kinase Signaling by β-Arrestins by Kiae Kim, Yeonjin Han, Longhan Duan, Ka Young Chung

    Published 2022-01-01
    “…Receptor-bound β-arrestins also initiate a second wave of signaling by scaffolding mitogen-activated protein kinase (MAPK) signaling components, MAPK kinase kinase, MAPK kinase, and MAPK. …”
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    Plant Mitogen-Activated Protein Kinase Cascades in Environmental Stresses by Li Lin, Jian Wu, Mingyi Jiang, Youping Wang

    Published 2021-02-01
    “…As important signaling modules in eukaryotes, plant mitogen-activated protein kinase (MAPK) cascades play a key role in regulating responses to the following four major environmental stresses: high salinity, drought, extreme temperature and insect and pathogen infections. …”
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    A Structural Characterisation of the Mitogen-Activated Protein Kinase Network in Cancer by Evangelos Chatzaroulas, Vytenis Sliogeris, Pedro Victori, Francesca M. Buffa, Sotiris Moschoyiannis, Roman Bauer

    Published 2022-05-01
    “…Here, we explored such topological characteristics in the example of a mitogen-activated protein kinase (MAPK) signalling network derived from published studies in cancer. …”
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    Mitogen-Activated Protein Kinase and Substrate Identification in Plant Growth and Development by Min Jiang, Youze Zhang, Peng Li, Jinjing Jian, Changling Zhao, Guosong Wen

    Published 2022-03-01
    “…Mitogen-activated protein kinases (MAPKs) form tightly controlled signaling cascades that play essential roles in plant growth, development, and defense response. …”
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    The effect of angiotensin II on mitogen-activated protein kinase in human cardiomyocytes by Chiming Wei, Marcelo G Cardarelli, Stephen W Downing, Joseph S McLaughlin

    Published 2000-12-01
    “…The role of angiotensin II (Ang II)-receptors on mitogen-activated protein kinase (MAPK) activation in cardiomyocytes remains controversial. …”
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    Expanding the Toolkit of Fluorescent Biosensors for Studying Mitogen Activated Protein Kinases in Plants by Kati Seitz, Patrick J. Krysan

    Published 2020-07-01
    “…Mitogen-activated protein kinases (MAPKs) are key regulators of numerous biological processes in plants. …”
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    Harnessing the role of mitogen-activated protein kinases against abiotic stresses in plants by Yasir Majeed, Yasir Majeed, Xi Zhu, Xi Zhu, Ning Zhang, Ning Zhang, Noor ul-Ain, Ali Raza, Fasih Ullah Haider, Huaijun Si, Huaijun Si

    Published 2023-02-01
    “…One of these mechanisms is the mitogen-activated protein kinase (MAPK) cascade, a signaling pathway used in the transduction of extracellular stimuli into intercellular responses. …”
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    Mitogen-activated protein kinase kinase 7 in inflammatory, cancer, and neurological diseases by Amada D. Caliz, Anastassiia Vertii, Vijay Fisch, Soonsang Yoon, Hyung-Jin Yoo, John F. Keaney, Shashi Kant

    Published 2022-10-01
    “…Stress-activated mitogen-activated protein kinase kinase 7 (MKK7) is a member of the dual-specificity mitogen-activated protein kinase family. …”
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    Identification and Analysis of Mitogen-Activated Protein Kinase (MAPK) Cascades in Fragaria vesca by Heying Zhou, Suyue Ren, Yuanfang Han, Qing Zhang, Ling Qin, Yu Xing

    Published 2017-08-01
    “…Mitogen-activated protein kinase (MAPK) cascades are highly conserved signaling modules in eukaryotes, including yeasts, plants and animals. …”
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    Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer by Florian Uhlitz, Philip Bischoff, Stefan Peidli, Anja Sieber, Alexandra Trinks, Mareen Lüthen, Benedikt Obermayer, Eric Blanc, Yana Ruchiy, Thomas Sell, Soulafa Mamlouk, Roberto Arsie, Tzu‐Ting Wei, Kathleen Klotz‐Noack, Roland F Schwarz, Birgit Sawitzki, Carsten Kamphues, Dieter Beule, Markus Landthaler, Christine Sers, David Horst, Nils Blüthgen, Markus Morkel

    Published 2021-10-01
    “…We defined patient‐overarching colorectal cancer cell clusters characterized by differential activities of oncogenic signaling pathways such as mitogen‐activated protein kinase and oncogenic traits such as replication stress. …”
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    Mitogen-Activated Protein Kinase and Exploratory Nuclear Receptor Crosstalk in Cancer Immunotherapy by Elke Burgermeister

    Published 2023-09-01
    “…The three major mitogen-activated protein kinase (MAPK) pathways (ERK1/2, p38, and JNK/SAPK) are upstream regulators of the nuclear receptor superfamily (NRSF). …”
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