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Mitogen-Activated Protein Kinase Pathway in Amyotrophic Lateral Sclerosis
Published 2021-08-01Subjects: Get full text
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Mitogen-Activated Protein Kinases (MAPKs) and Cholangiocarcinoma: The Missing Link
Published 2019-09-01Subjects: Get full text
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Targeting the RAS pathway by mitogen-activated protein kinase inhibitors
Published 2015-12-01“…Now data show that neuroblastoma RAS (NRAS) and even Harvey RAS (HRAS) mutations could be predictive markers for treatment with mitogen-activated protein kinase (MEK) inhibitors. This review discusses recent preclinical and clinical studies of MEK inhibitors in BRAF and RAS mutant cancer. …”
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Comprehensive analysis of mitogen-activated protein kinase cascades in chrysanthemum
Published 2018-06-01Subjects: Get full text
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Scaffolding of Mitogen-Activated Protein Kinase Signaling by β-Arrestins
Published 2022-01-01“…Receptor-bound β-arrestins also initiate a second wave of signaling by scaffolding mitogen-activated protein kinase (MAPK) signaling components, MAPK kinase kinase, MAPK kinase, and MAPK. …”
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Mitogen-Activated Protein Kinase 4-Regulated Metabolic Networks
Published 2022-01-01Subjects: Get full text
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Plant Mitogen-Activated Protein Kinase Cascades in Environmental Stresses
Published 2021-02-01“…As important signaling modules in eukaryotes, plant mitogen-activated protein kinase (MAPK) cascades play a key role in regulating responses to the following four major environmental stresses: high salinity, drought, extreme temperature and insect and pathogen infections. …”
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A Structural Characterisation of the Mitogen-Activated Protein Kinase Network in Cancer
Published 2022-05-01“…Here, we explored such topological characteristics in the example of a mitogen-activated protein kinase (MAPK) signalling network derived from published studies in cancer. …”
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Mitogen-Activated Protein Kinase and Substrate Identification in Plant Growth and Development
Published 2022-03-01“…Mitogen-activated protein kinases (MAPKs) form tightly controlled signaling cascades that play essential roles in plant growth, development, and defense response. …”
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The effect of angiotensin II on mitogen-activated protein kinase in human cardiomyocytes
Published 2000-12-01“…The role of angiotensin II (Ang II)-receptors on mitogen-activated protein kinase (MAPK) activation in cardiomyocytes remains controversial. …”
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Expanding the Toolkit of Fluorescent Biosensors for Studying Mitogen Activated Protein Kinases in Plants
Published 2020-07-01“…Mitogen-activated protein kinases (MAPKs) are key regulators of numerous biological processes in plants. …”
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p38 mitogen‐activated protein kinase: Functions and targeted therapy in diseases
Published 2023-09-01Subjects: Get full text
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Harnessing the role of mitogen-activated protein kinases against abiotic stresses in plants
Published 2023-02-01“…One of these mechanisms is the mitogen-activated protein kinase (MAPK) cascade, a signaling pathway used in the transduction of extracellular stimuli into intercellular responses. …”
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Mitogen-activated protein kinase kinase 7 in inflammatory, cancer, and neurological diseases
Published 2022-10-01“…Stress-activated mitogen-activated protein kinase kinase 7 (MKK7) is a member of the dual-specificity mitogen-activated protein kinase family. …”
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Identification and Analysis of Mitogen-Activated Protein Kinase (MAPK) Cascades in Fragaria vesca
Published 2017-08-01“…Mitogen-activated protein kinase (MAPK) cascades are highly conserved signaling modules in eukaryotes, including yeasts, plants and animals. …”
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Mitogen-Activated Protein Kinase and Nuclear Hormone Receptor Crosstalk in Cancer Immunotherapy
Published 2023-09-01Get full text
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Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer
Published 2021-10-01“…We defined patient‐overarching colorectal cancer cell clusters characterized by differential activities of oncogenic signaling pathways such as mitogen‐activated protein kinase and oncogenic traits such as replication stress. …”
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Mitogen-Activated Protein Kinase and Exploratory Nuclear Receptor Crosstalk in Cancer Immunotherapy
Published 2023-09-01“…The three major mitogen-activated protein kinase (MAPK) pathways (ERK1/2, p38, and JNK/SAPK) are upstream regulators of the nuclear receptor superfamily (NRSF). …”
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Regulation of GATA-2 phosphorylation by mitogen-activated protein kinase and interleukin-3
Published 1995Journal article