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181
Discovery of Human sORF-Encoded Polypeptides (SEPs) in Cell Lines and Tissue
Published 2015“…The discovery of novel SEPs increases the size of the genome and the proteome and provides insights into the molecular biology of mammalian cells, such as the prevalent usage of non-AUG start codons. …”
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182
A review on breast cancer in Iraq and future therapies insights
Published 2022-03-01“…To fight cancer, there is an urgent need to search for new effective anticancer therapies that alter the molecular biology of tumor cells, stimulate the immune system, or specifically deliver chemotherapy factors directly to cancer cells without affecting normal cells and reducing the side effects of treatments. …”
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183
Nanoengineered approaches to improve the efficacy of targeted drug delivery for the treatment of malignancy: a comprehensive review
Published 2023-10-01“…The main body of the abstract The development of innovative and effective targeted therapies for malignancy relies on alterations in the molecular biology of cancerous cells. Given the nonselective destruction of healthy cells, the harmful effects of existing chemotherapy drugs, and the development of multidrug resistance, has thrived the development of novel carriers for improved targeting efficacy of anticancer drugs. …”
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184
Biological membrane lipids in norm and pathology (literature review)
Published 2017-09-01“…Because the development of various pathological processes and conditions accompanied by molecular biological changes of cell membranes, it primarily concerns erythrocyte membrane, as they are composed of many easily-oxidized phospholipids and they come in contact with relatively high concentrations of oxygen, it is important to examine the role of erythrocyte lipid layer. …”
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185
Subcutaneous Transplantation of Bovine and Human Adrenocortical Cells in Collagen Gel in scid Mice
Published 1999-11-01“…Subcutaneous transplantation of bovine or human primary adrenocortical cells in collagen provides a model for the study of the physiology, cell biology, and molecular biology of adrenocortical cells in a three-dimensional vascularized tissue structure in a host animal.…”
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186
The Potential Use of Exosomes in Anti-Cancer Effect Induced by Polarized Macrophages
Published 2023-03-01“…Finding novel, highly efficient targeted therapies based on modifications in the molecular biology of tumor cells is essential to reduce the indiscriminate destruction of healthy cells. …”
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187
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188
Potential downstream targets of the polyamine pathway and their roles in embryonic stem cell renewal
Published 2015Get full text
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189
High-throughput whole-genome sequencing of E14 mouse embryonic stem cells
Published 2015-03-01“…The identified variants are enriched on intergenic regions, but several thousands reside on gene exons and regulatory regions, such as promoters, enhancers, splicing site and untranslated regions of RNA, thus indicating high probability of an important functional impact on the molecular biology of these cells. We created a new E14 genome assembly including the new identified variants and used it to map reads from next generation sequencing data generated in our laboratory or in others on E14 cell line. …”
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190
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191
Applying ChIP and ChIA-PET to identify p300, CTCF and Lamin B binding sites in stem cells
Published 2009Get full text
Final Year Project (FYP) -
192
Generation of highly pure motor neurons from human induced pluripotent stem cells
Published 2022-03-01Get full text
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193
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Protocol for generation of PD-modeling-induced neurons and detection of α-synuclein forms
Published 2024-12-01Get full text
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195
Cytochrome P450 1B1 Overexpression in Cervical Cancers: Cross-sectional Study
Published 2021-10-01“…Recently, the rational approach for the discovery of new therapies for cervical cancer is based on the alterations in the molecular biology of cancer cells. One of the emerging molecular changes in cancer cells is the aberrant expression of cytochrome P450 1B1 (CYP1B1). …”
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196
Rapid regulation of protein activity in fission yeast
Published 2008“…Despite the availability of extensive set of genetic, molecular biological, biochemical and cell biological tools for analysis of protein function in fission yeast, studies are often hampered by the lack of an effective method allowing for the rapid regulation of protein level or protein activity. …”
Journal article -
197
Rho GTPases and regulation of cell migration, polarization and adhesion proteins in wounding assay of human corneal epithelial cells
Published 2012Get full text
Final Year Project (FYP) -
198
Prolonged hypoxia promotes enrichment of cytosolic EZH2 in breast cancer stem cells via a HIF-1α-independent mechanism
Published 2020Get full text
Final Year Project (FYP) -
199
Basic characterization of antibodies targeting receptors of the tumor necrosis factor receptor superfamily
Published 2023-03-01“…The presented protocols only require standard molecular biological equipment, eukaryotic cell culture and plate readers for the quantification of luminescent and colorimetric signals.…”
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200
In-depth analysis of lymph node metastasis-related sialylated protein profiling and their clinical and biological significance in colorectal cancer using mass spectrometry and mult...
Published 2024-11-01“…Then, we further confirmed that patients in different phenotypes had different prognosis, molecular biological characteristics, immune cell infiltration and could be closely linked to three previously reported immune phenotypes: immune-excluded (Phenotype A), immune-desert (Phenotype B), and immune-inflamed (Phenotype C). …”
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