Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations by Mélissanne de Wispelaere, Guangyan Du, Katherine A. Donovan, Tinghu Zhang, Nicholas A. Eleuteri, Jingting C. Yuan, Joann Kalabathula, Radosław P. Nowak, Eric S. Fischer, Nathanael S. Gray, Priscilla L. Yang

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Pharmacological Inhibition of Epac1 Averts Ferroptosis Cell Death by Preserving Mitochondrial Integrity by Nshunge Musheshe, Asmaa Oun, Angélica María Sabogal-Guáqueta, Marina Trombetta-Lima, Sarah C. Mitchel, Ahmed Adzemovic, Oliver Speek, Francesca Morra, Christina H. J. T. van der Veen, Frank Lezoualc’h, Xiaodong Cheng, Martina Schmidt, Amalia M. Dolga

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m1A Regulated Genes Modulate PI3K/AKT/mTOR and ErbB Pathways in Gastrointestinal Cancer by Yueshui Zhao, Qijie Zhao, Parham Jabbarzadeh Kaboli, Jing Shen, Mingxing Li, Xu Wu, Jianhua Yin, Hanyu Zhang, Yuanlin Wu, Ling Lin, Lingling Zhang, Lin Wan, Qinglian Wen, Xiang Li, Chi Hin Cho, Tao Yi, Jing Li, Zhangang Xiao

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Therapeutic prospects of ceRNAs in COVID-19 by Lin Liu, Lin Liu, Lin Liu, Yao Zhang, Yao Zhang, Yao Zhang, Yu Chen, Yu Chen, Yu Chen, Yueshui Zhao, Yueshui Zhao, Yueshui Zhao, Jing Shen, Jing Shen, Jing Shen, Xu Wu, Xu Wu, Xu Wu, Mingxing Li, Mingxing Li, Mingxing Li, Meijuan Chen, Xiaobing Li, Yuhong Sun, Li Gu, Wanping Li, Fang Wang, Lei Yao, Zhuo Zhang, Zhangang Xiao, Zhangang Xiao, Zhangang Xiao, Zhangang Xiao, Fukuan Du, Fukuan Du, Fukuan Du

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Resistance to a Nucleoside Analog Antiviral Drug from More Rapid Extension of Drug-Containing Primers by Han Chen, Jessica L. Lawler, David J. Filman, James M. Hogle, Donald M. Coen

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Dietary thiols accelerate aging of C. elegans by Ivan Gusarov, Ilya Shamovsky, Bibhusita Pani, Laurent Gautier, Svetlana Eremina, Olga Katkova-Zhukotskaya, Alexander Mironov, Alexander А. Makarov, Evgeny Nudler

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The multifaceted roles of GSDME-mediated pyroptosis in cancer: therapeutic strategies and persisting obstacles by Yixiang Hu, Ya Liu, Lijuan Zong, Wenyou Zhang, Renzhu Liu, Qichang Xing, Zheng Liu, Qingzi Yan, Wencan Li, Haibo Lei, Xiang Liu

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SPIN-AI: A Deep Learning Model That Identifies Spatially Predictive Genes by Kevin Meng-Lin, Choong-Yong Ung, Cheng Zhang, Taylor M. Weiskittel, Philip Wisniewski, Zhuofei Zhang, Shyang-Hong Tan, Kok-Siong Yeo, Shizhen Zhu, Cristina Correia, Hu Li

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Application of a Substrate-Mediated Selection with c-Src Tyrosine Kinase to a DNA-Encoded Chemical Library by Dongwook Kim, Yixing Sun, Dan Xie, Kyle E. Denton, Hao Chen, Hang Lin, Michael K. Wendt, Carol Beth Post, Casey J. Krusemark

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Regenerative Therapy Prevents Heart Failure Progression in Dyssynchronous Nonischemic Narrow QRS Cardiomyopathy by Satsuki Yamada, D. Kent Arrell, Almudena Martinez‐Fernandez, Atta Behfar, Garvan C. Kane, Carmen M. Perez‐Terzic, Ruben J. Crespo‐Diaz, Robert J. McDonald, Saranya P. Wyles, Jelena Zlatkovic‐Lindor, Timothy J. Nelson, Andre Terzic

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m5C RNA Methylation Primarily Affects the ErbB and PI3K–Akt Signaling Pathways in Gastrointestinal Cancer by Shixin Xiang, Shixin Xiang, Yongshun Ma, Yongshun Ma, Jing Shen, Jing Shen, Yueshui Zhao, Yueshui Zhao, Xu Wu, Xu Wu, Mingxing Li, Mingxing Li, Xiao Yang, Parham Jabbarzadeh Kaboli, Parham Jabbarzadeh Kaboli, Fukuan Du, Fukuan Du, Huijiao Ji, Huijiao Ji, Yuan Zheng, Xiang Li, Jing Li, Qinglian Wen, Zhangang Xiao, Zhangang Xiao

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BAMscale: quantification of next-generation sequencing peaks and generation of scaled coverage tracks by Lorinc S. Pongor, Jacob M. Gross, Roberto Vera Alvarez, Junko Murai, Sang-Min Jang, Hongliang Zhang, Christophe Redon, Haiqing Fu, Shar-Yin Huang, Bhushan Thakur, Adrian Baris, Leonardo Marino-Ramirez, David Landsman, Mirit I. Aladjem, Yves Pommier

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Downregulation of PDIA3 inhibits gastric cancer cell growth through cell cycle regulation by Min Yang, Qianxiu Li, Huan Yang, Yifan Li, Lan Lu, Xu Wu, Yubin Liu, Wanping Li, Jing Shen, Zhangang Xiao, Yueshui Zhao, Fukuan Du, Yu Chen, Shuai Deng, Chi Hin Cho, Xiaobing Li, Mingxing Li

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Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma by Xiuqin Jia, Ming Xin, Juanjuan Xu, Xindong Xiang, Xuan Li, Yuhan Jiao, Lulin Wang, Jingjing Jiang, Feng Pang, Xianzhen Zhang, Jian Zhang

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Effects of ripasudil, a ROCK inhibitor, on retinal edema and nonperfusion area in a retinal vein occlusion murine model by Yoshifumi Hida, Shinsuke Nakamura, Anri Nishinaka, Yuki Inoue, Masamitsu Shimazawa, Hideaki Hara

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Daily intake of β-cryptoxanthin prevents bone loss by preferential disturbance of osteoclastic activation in ovariectomized mice by Kakeru Ozaki, Maika Okamoto, Kazuya Fukasawa, Takashi Iezaki, Yuki Onishi, Yukio Yoneda, Minoru Sugiura, Eiichi Hinoi

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Allosteric inhibition of a stem cell RNA-binding protein by an intermediary metabolite by Carina C Clingman, Laura M Deveau, Samantha A Hay, Ryan M Genga, Shivender MD Shandilya, Francesca Massi, Sean P Ryder

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Prediction of pharmacological activities from chemical structures with graph convolutional neural networks by Miyuki Sakai, Kazuki Nagayasu, Norihiro Shibui, Chihiro Andoh, Kaito Takayama, Hisashi Shirakawa, Shuji Kaneko

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Negative modulation of mitochondrial calcium uniporter complex protects neurons against ferroptosis by Alejandro Marmolejo-Garza, Inge E. Krabbendam, Minh Danh Anh Luu, Famke Brouwer, Marina Trombetta-Lima, Osman Unal, Shane J. O’Connor, Naďa Majerníková, Carolina R. S. Elzinga, Cristina Mammucari, Martina Schmidt, Muniswamy Madesh, Erik Boddeke, Amalia M. Dolga

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<i>tert</i>-Butyl Nitrite-Induced Radical Nitrile Oxidation Cycloaddition: Synthesis of Isoxazole/Isoxazoline-Fused Benzo 6/7/8-membered Oxacyclic Ketones by Jian-Kang Cao, Tian-Zheng Cao, Qian-Wen Yue, Ying Ma, Chuan-Ming Yang, Hong-Xi Zhang, Ya-Chen Li, Qiao-Ke Dong, Yan-Ping Zhu, Yuan-Yuan Sun

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