Enzymatic enhancing of triplet–triplet annihilation upconversion by breaking oxygen quenching for background-free biological sensing by Ling Huang, Timmy Le, Kai Huang, Gang Han

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Solution Structure of a MYC Promoter G‑Quadruplex with 1:6:1 Loop Length by Jonathan Dickerhoff, Buket Onel, Luying Chen, Yuwei Chen, Danzhou Yang

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Single-molecule imaging reveals multiple pathways for the recruitment of translesion polymerases after DNA damage by Elizabeth S. Thrall, James E. Kath, Seungwoo Chang, Joseph J. Loparo

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Nicotine enhances object recognition memory through inhibition of voltage-dependent potassium 7 channels in the medial prefrontal cortex of mice by Hirohito Esaki, Shoma Izumi, Akari Fukao, Naoya Nishitani, Satoshi Deyama, Katsuyuki Kaneda

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MSI2 is required for maintaining activated myelodysplastic syndrome stem cells by James Taggart, Tzu-Chieh Ho, Elianna Amin, Haiming Xu, Trevor S. Barlowe, Alexendar R. Perez, Benjamin H. Durham, Patrick Tivnan, Rachel Okabe, Arthur Chow, Ly Vu, Sun Mi Park, Camila Prieto, Christopher Famulare, Minal Patel, Christopher J. Lengner, Amit Verma, Gail Roboz, Monica Guzman, Virginia M. Klimek, Omar Abdel-Wahab, Christina Leslie, Stephen D. Nimer, Michael G. Kharas

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A novel dendrimer-based complex co-modified with cyclic RGD hexapeptide and penetratin for noninvasive targeting and penetration of the ocular posterior segment by Xiucheng Yang, Lihua Wang, Lin Li, Meishan Han, Shengnan Tang, Tengteng Wang, Junping Han, Xiaoyan He, Xiuting He, Aiping Wang, Kaoxiang Sun

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Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis by Takashi Iezaki, Tetsuhiro Horie, Kazuya Fukasawa, Makoto Kitabatake, Yuka Nakamura, Gyujin Park, Yuki Onishi, Kakeru Ozaki, Takashi Kanayama, Manami Hiraiwa, Yuka Kitaguchi, Katsuyuki Kaneda, Takayuki Manabe, Yasuhito Ishigaki, Mutsuhito Ohno, Eiichi Hinoi

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Engineered TCR-T Cell Immunotherapy in Anticancer Precision Medicine: Pros and Cons by Qijie Zhao, Qijie Zhao, Qijie Zhao, Yu Jiang, Yu Jiang, Shixin Xiang, Shixin Xiang, Parham Jabbarzadeh Kaboli, Parham Jabbarzadeh Kaboli, Jing Shen, Jing Shen, Yueshui Zhao, Yueshui Zhao, Xu Wu, Xu Wu, Fukuan Du, Fukuan Du, Mingxing Li, Mingxing Li, Chi Hin Cho, Chi Hin Cho, Jing Li, Qinglian Wen, Tao Liu, Tao Yi, Zhangang Xiao, Zhangang Xiao

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Substrate sequence selectivity of APOBEC3A implicates intra-DNA interactions by Tania V. Silvas, Shurong Hou, Wazo Myint, Ellen Nalivaika, Mohan Somasundaran, Brian A. Kelch, Hiroshi Matsuo, Nese Kurt Yilmaz, Celia A. Schiffer

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Anti-diabetic effects of astaxanthin-rich extract derived from Paracoccus carotinifaciens on pancreatic β cells by Hikari Hirakida, Shinsuke Nakamura, Satoshi Inagaki, Shohei Tsuji, Masahiro Hayashi, Masamitsu Shimazawa, Hideaki Hara

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Relatlimab: a novel drug targeting immune checkpoint LAG-3 in melanoma therapy by Jingjing Su, Yiting Fu, Zitong Cui, Zain Abidin, Jingsong Yuan, Xinmiao Zhang, Runmin Li, Chunzhen Zhao

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Involvement of endoplasmic reticulum stress in rotenone-induced leber hereditary optic neuropathy model and the discovery of new therapeutic agents by Yakumo Aoyama, Satoshi Inagaki, Kota Aoshima, Yuki Iwata, Shinsuke Nakamura, Hideaki Hara, Masamitsu Shimazawa

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Survival motor neuron protein regulates oxidative stress and inflammatory response in microglia of the spinal cord in spinal muscular atrophy by Shiori Ando, Daiki Osanai, Kei Takahashi, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki Hara

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Noradrenergic stimulation of α1 adrenoceptors in the medial prefrontal cortex mediates acute stress-induced facilitation of seizures in mice by Kazuhei Niitani, Shiho Ito, Shintaro Wada, Shoma Izumi, Naoya Nishitani, Satoshi Deyama, Katsuyuki Kaneda

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The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis by S. A. Baechler, V. M. Factor, I. Dalla Rosa, A. Ravji, D. Becker, S. Khiati, L. M. Miller Jenkins, M. Lang, C. Sourbier, S. A. Michaels, L. M. Neckers, H. L. Zhang, A. Spinazzola, S. N. Huang, J. U. Marquardt, Y. Pommier

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Mechanistic study of silica nanoparticles on the size-dependent retinal toxicity in vitro and in vivo by Zhuhong Zhang, Laien Zhao, Yuanyuan Ma, Jia Liu, Yanmei Huang, Xiaoxuan Fu, Shengjun Peng, Xiaojie Wang, Yun Yang, Xiaoyan Zhang, Wanru Ding, Jinguo Yu, Yanping Zhu, Hua Yan, Shubin Yang

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ROS generation and p-38 activation contribute to montmorillonite-induced corneal toxicity in vitro and in vivo by Jia Liu, Shubin Yang, Laien Zhao, Feng Jiang, Jianchao Sun, Shengjun Peng, Ruikang Zhao, Yanmei Huang, Xiaoxuan Fu, Rongrui Luo, Yu Jiang, Zelin Li, Nan Wang, Tengzheng Fang, Zhuhong Zhang

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GTP-State-Selective Cyclic Peptide Ligands of K‑Ras(G12D) Block Its Interaction with Raf by Ziyang Zhang, Rong Gao, Qi Hu, Hayden Peacock, D. Matthew Peacock, Shizhong Dai, Kevan M. Shokat, Hiroaki Suga

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Specialized Metabolites Reveal Evolutionary History and Geographic Dispersion of a Multilateral Symbiosis by Taise T. H. Fukuda, Eric J. N. Helfrich, Emily Mevers, Weilan G. P. Melo, Ethan B. Van Arnam, David R. Andes, Cameron R. Currie, Monica T. Pupo, Jon Clardy

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Berberine regulates UCP1 expression by reshaping the conformation of quadruplex formed by the element of the UCP1 gene promoter by Wang Qiuhui, Xu Xingke, Jiang Xiaoqing, Yin Fei

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