3D CRISPR screen in prostate cancer cells reveals PARP inhibitor sensitization through TBL1XR1-SMC3 interaction by Huan Zhang, Huanyao Gao, Yayun Gu, August John, Lixuan Wei, Minhong Huang, Jia Yu, Adeyemi A. Adeosun, Richard M. Weinshilboum, Liewei Wang

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PCC0208017, a novel small-molecule inhibitor of MARK3/MARK4, suppresses glioma progression in vitro and in vivo by Fangfang Li, Zongliang Liu, Heyuan Sun, Chunmei Li, Wenyan Wang, Liang Ye, Chunhong Yan, Jingwei Tian, Hongbo Wang

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Properties of neurons in the superficial laminae of trigeminal nucleus caudalis by Bruno Pradier, Samuel J. McCormick, Ayumi C. Tsuda, Rudy W. Chen, Abigail L. Atkinson, Mollie R. Westrick, Caroline L. Buckholtz, Julie A. Kauer

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Endothelial and mural laminin-α5 contributes to neurovascular integrity maintenance by Abhijit Nirwane, Minkyung Kang, Aravinthan Adithan, Vrishni Maharaj, Felicia Nguyen, Elliot Santaella Aguilar, Ava Nasrollahi, Yao Yao

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A Novel High Resolution In Vivo Digital Imaging System for the Evaluation of Experimental Cataract in Diabetic Rats by Sokichi Kametaka, Takafumi Kasahara, Mayumi Ueo, Mariko Takenaka, Maki Saito, Kenji Sakamoto, Tsutomu Nakahara, Kunio Ishii

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Glucocorticoids mediate transcriptome‐wide alternative polyadenylation: Potential mechanistic and clinical implications by Thanh Thanh L. Nguyen, Duan Liu, Huanyao Gao, Zhenqing Ye, Jeong‐Heon Lee, Lixuan Wei, Jia Yu, Lingxin Zhang, Liewei Wang, Tamas Ordog, Richard M. Weinshilboum

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Vitamin D supplementation is effective for olanzapine-induced dyslipidemia by Zijian Zhou, Takuya Nagashima, Takuya Nagashima, Chihiro Toda, Mone Kobayashi, Takahide Suzuki, Kazuki Nagayasu, Hisashi Shirakawa, Satoshi Asai, Shuji Kaneko

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Molecular Integrative Analysis of the Inhibitory Effects of Dipeptides on Amyloid β Peptide 1–42 Polymerization by Nan Yuan, Lianmeng Ye, Yan Sun, Hao Wu, Zhengpan Xiao, Wanmeng Fu, Zuqian Chen, Yechun Pei, Yi Min, Dayong Wang

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Inhibition of Endoplasmic Reticulum Stress Preserves the Integrity of Blood-Spinal Cord Barrier in Diabetic Rats Subjected to Spinal Cord Injury by Zili He, Shuang Zou, Jiayu Yin, Zhengzheng Gao, Yanlong Liu, Yanqing Wu, Huacheng He, Yulong Zhou, Qingqing Wang, Jiawei Li, Fenzan Wu, Hua-Zi Xu, Xiaofeng Jia, Jian Xiao

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Targeting hypoxia-inducible factors for breast cancer therapy: A narrative review by Shuang Luo, Shuang Luo, Shuang Luo, Shuang Luo, Yu Jiang, Anfu Zheng, Anfu Zheng, Anfu Zheng, Yueshui Zhao, Yueshui Zhao, Yueshui Zhao, Xu Wu, Xu Wu, Xu Wu, Mingxing Li, Mingxing Li, Mingxing Li, Fukuan Du, Fukuan Du, Fukuan Du, Yu Chen, Yu Chen, Yu Chen, Shuai Deng, Shuai Deng, Shuai Deng, Meijuan Chen, Meijuan Chen, Meijuan Chen, Wanping Li, Wanping Li, Wanping Li, Xiaobing Li, Xiaobing Li, Xiaobing Li, Li Gu, Li Gu, Li Gu, Yuhong Sun, Yuhong Sun, Yuhong Sun, Zhangang Xiao, Zhangang Xiao, Jing Shen, Jing Shen, Jing Shen

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Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice by Kai Mao, Gabriela Farias Quipildor, Tahmineh Tabrizian, Ardijana Novaj, Fangxia Guan, Ryan O. Walters, Fabien Delahaye, Gene B. Hubbard, Yuji Ikeno, Keisuke Ejima, Peng Li, David B. Allison, Hossein Salimi-Moosavi, Pedro J. Beltran, Pinchas Cohen, Nir Barzilai, Derek M. Huffman

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Fragment-based drug nanoaggregation reveals drivers of self-assembly by Chen Chen, You Wu, Shih-Ting Wang, Naxhije Berisha, Mandana T. Manzari, Kristen Vogt, Oleg Gang, Daniel A. Heller

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Amelioration by the Natural Polyamine Spermine of Cartilage and Bone Destruction in Rats With Collagen-Induced Arthritis by Takashi Iezaki, Eiichi Hinoi, Tomomi Yamamoto, Ryo Ishiura, Shinya Ogawa, Yukio Yoneda

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Immunomodulatory Mechanism and Potential Application of Dental Pulp-Derived Stem Cells in Immune-Mediated Diseases by Qi Min, Liqiong Yang, Hua Tian, Lu Tang, Zhangang Xiao, Jing Shen

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Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling by Daniel T. D. Jones, Andrew N. Dates, Shaun D. Rawson, Maggie M. Burruss, Colin H. Lipper, Stephen C. Blacklow

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Efficacy of Prednisolone in Generated Myotubes Derived From Fibroblasts of Duchenne Muscular Dystrophy Patients by Tsubasa Kameyama, Tsubasa Kameyama, Kazuki Ohuchi, Kazuki Ohuchi, Michinori Funato, Shiori Ando, Shiori Ando, Satoshi Inagaki, Satoshi Inagaki, Arisu Sato, Arisu Sato, Junko Seki, Chizuru Kawase, Kazuhiro Tsuruma, Ichizo Nishino, Shinsuke Nakamura, Masamitsu Shimazawa, Takashi Saito, Shin’ichi Takeda, Hideo Kaneko, Hideaki Hara

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A novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironment by Cheng-Hsin Wei, Lu Huang, Blair Kreh, Xiuxia Liu, Liliya Tyutyunyk-Massey, Masanori Kawakami, Zibo Chen, Mi Shi, Serguei Kozlov, King C. Chan, Thorkell Andresson, Mary Carrington, Vidyasagar Vuligonda, Martin E. Sanders, Amir Horowitz, Patrick Hwu, Weiyi Peng, Ethan Dmitrovsky, Xi Liu

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Network Pharmacology Based Research on the Combination Mechanism Between Escin and Low Dose Glucocorticoids in Anti-rheumatoid Arthritis by Leiming Zhang, Yanan Huang, Chuanhong Wu, Yuan Du, Peng Li, Meiling Wang, Xinlin Wang, Yanfang Wang, Yanfei Hao, Tian Wang, Baofeng Fan, Zhuye Gao, Fenghua Fu

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β-caryophyllene improves cerebral ischemia reperfusion injury in rats via Notch1/NF-κB signal axis by LIU Jingdong, CHEN Sha, WANG Yuchun, LIU Shengwei, RAO Jiangyan, WANG Qian, DENG Ling, WANG Xuan, DONG Zhi

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RIPK3 Suppresses the Progression of Spontaneous Intestinal Tumorigenesis by Qun Zhao, Jian Guo, Xinran Cheng, Yingying Liao, Yun Bi, Yingxia Gong, Xudong Zhang, Yang Guo, Xianhui Wang, Wei Yu, Shu Jin, Yan Tan, Xianjun Yu

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