The Astragaloside IV Derivative LS-102 Ameliorates Obesity-Related Nephropathy by Li Z, Yang W, Yang Y, Wu J, Luo P, Liu Y

“…Ziyu Li,1 Wei Yang,1 Yong Yang,1 Jianbo Wu,2 Pei Luo,3 Yong Liu1,4,5 1Department of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 2Drug Discovery Research Center, Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 3State Key Laboratories for Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, People’s Republic of China; 4Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, People’s Republic of China; 5Medical Equipment Department, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People’s Republic of ChinaCorrespondence: Yong Liu, Email liuyong@swmu.edu.cnBackground: Astragaloside IV is the most important bioactive component of Radix Astragali. …”
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Development and validation of a radiomics signature for clinically significant portal hypertension in cirrhosis (CHESS1701): a prospective multicenter studyResearch in context by Fuquan Liu, Zhenyuan Ning, Yanna Liu, Dengxiang Liu, Jie Tian, Hongwu Luo, Weimin An, Yifei Huang, Jialiang Zou, Chuan Liu, Changchun Liu, Lei Wang, Zaiyi Liu, Ruizhao Qi, Changzeng Zuo, Qingge Zhang, Jitao Wang, Dawei Zhao, Yongli Duan, Baogang Peng, Xingshun Qi, Yuening Zhang, Yongping Yang, Jinlin Hou, Jiahong Dong, Zhiwei Li, Huiguo Ding, Yu Zhang, Xiaolong Qi

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Intra-host variation and evolutionary dynamics of SARS-CoV-2 populations in COVID-19 patients by Yanqun Wang, Daxi Wang, Lu Zhang, Wanying Sun, Zhaoyong Zhang, Weijun Chen, Airu Zhu, Yongbo Huang, Fei Xiao, Jinxiu Yao, Mian Gan, Fang Li, Ling Luo, Xiaofang Huang, Yanjun Zhang, Sook-san Wong, Xinyi Cheng, Jingkai Ji, Zhihua Ou, Minfeng Xiao, Min Li, Jiandong Li, Peidi Ren, Ziqing Deng, Huanzi Zhong, Xun Xu, Tie Song, Chris Ka Pun Mok, Malik Peiris, Nanshan Zhong, Jingxian Zhao, Yimin Li, Junhua Li, Jincun Zhao

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Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis by Haruko Nakano, Itsunari Minami, Daniel Braas, Herman Pappoe, Xiuju Wu, Addelynn Sagadevan, Laurent Vergnes, Kai Fu, Marco Morselli, Christopher Dunham, Xueqin Ding, Adam Z Stieg, James K Gimzewski, Matteo Pellegrini, Peter M Clark, Karen Reue, Aldons J Lusis, Bernard Ribalet, Siavash K Kurdistani, Heather Christofk, Norio Nakatsuji, Atsushi Nakano

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cN+pN0 disease does not portend a less favorable prognosis compared with cN0pN0 in patients with resected oral cavity squamous cell carcinoma by Chien‐Yu Lin, Li‐Yu Lee, Nai‐Ming Cheng, Shu Ru Lee, Chi‐Ying Tsai, Chuen Hsueh, Kang‐Hsing Fan, Hung‐Ming Wang, Chia‐Hsun Hsieh, Shu‐Hang Ng, Chih‐Hua Yeh, Chih‐Hung Lin, Chung‐Kan Tsao, Tuan‐Jen Fang, Shiang‐Fu Huang, Li‐Ang Lee, Chung‐Jan Kang, Ku‐Hao Fang, Yu‐Chien Wang, Wan‐Ni Lin, Li‐Jen Hsin, Tzu‐Chen Yen, Chun‐Ta Liao

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Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease by Jeremy F. Strain, Matthew R. Brier, Aaron Tanenbaum, Brian A. Gordon, John E. McCarthy, Aylin Dincer, Daniel S. Marcus, Jasmeer P. Chhatwal, Neill R. Graff-Radford, Gregory S. Day, Christian la Fougère, Richard J. Perrin, Stephen Salloway, Peter R. Schofield, Igor Yakushev, Takeshi Ikeuchi, Jonathan Vöglein, John C. Morris, Tammie L.S. Benzinger, Randall J. Bateman, Beau M. Ances, Abraham Z. Snyder

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Systematically evaluating DOTATATE and FDG as PET immuno-imaging tracers of cardiovascular inflammation by Yohana C. Toner, Adam A. Ghotbi, Sonum Naidu, Ken Sakurai, Mandy M. T. van Leent, Stefan Jordan, Farideh Ordikhani, Letizia Amadori, Alexandros Marios Sofias, Elizabeth L. Fisher, Alexander Maier, Nathaniel Sullivan, Jazz Munitz, Max L. Senders, Christian Mason, Thomas Reiner, Georgios Soultanidis, Jason M. Tarkin, James H. F. Rudd, Chiara Giannarelli, Jordi Ochando, Carlos Pérez-Medina, Andreas Kjaer, Willem J. M. Mulder, Zahi A. Fayad, Claudia Calcagno

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ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016 by Enriqueta Felip, Josep Tabernero, Maria De Santis, Emile Voest, Mark Robson, Fatima Cardoso, Elisabeth G E de Vries, Fedro Alessandro Peccatori, Svetlana Jezdic, Giannis Mountzios, Smita Bhatia, Alexandru Eniu, Luzia Travado, Ulrich Keilholz, Jonas Bergh, Jan Buckner, Friedrich Stiefel, Ahmad Awada, Cristiana Sessa, Olivier Michielin, Marc Ernstoff, Ben Markman, Lisa Licitra, Rossana Berardi, Jill Gilbert, Lidia Schapira, Eva Schernhammer, Jeffrey S Weber, Heinz-Josef Lenz, Piotr Rutkowski, Jennifer Duff, Axel Grothey, Yuichiro Ohe, Saskia Litiere, Hans Wildiers, Christian Dittrich, Michael Kosty, Doug Pyle, Nagi El-Saghir, Jean-Pierre Lotz, Pia Österlund, Nicholas Pavlidis, Gunta Purkalne, Susana Banerjee, Jan Bogaerts, Paolo Casali, Edward Chu, Julia Lee Close, Bertrand Coiffier, Roisin Connolly, Sarah Coupland, Luigi De Petris, Don S Dizon, Linda R Duska, Martin F Fey, Nicolas Girard, Andor W J M Glaudemans, Priya K Gopalan, Stephen M Hahn, Diana Hanna, Christian Herold, Jørn Herrstedt, Krisztian Homicsko, Dennie V Jones, Lorenz Jost, Saad Khan, Alexander Kiss, Claus-Henning Köhne, Rainer Kunstfeld, Stuart Lichtman, Thomas Lion, Lifang Liu, Patrick J Loehrer, Merry Jennifer Markham, Marius Mayerhoefer, Johannes G Meran, Elizabeth Charlotte Moser, Timothy Moynihan, Torsten Nielsen, Kjell Öberg, Antonio Palumbo, Michael Pfeilstöcker, Chandrajit Raut, Scot C Remick, Roberto Salgado, Martin Schlumberger, Hans-Joachim Schmoll, Lowell Schnipper, Charles L Shapiro, Julie Steele, Cora N Sternberg, Florian Strasser, Roger Stupp, Richard Sullivan, Marcel Verheij, Everett Vokes, Jamie Von Roenn, Yosef Yarden

“…Thus, several new chapters on technical contents such as molecular pathology, translational research or molecular imaging and on conceptual attitudes towards human principles like genetic counselling or survivorship have been integrated in the GC. …”
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lncRNA CISAL Inhibits BRCA1 Transcription by Forming a Tertiary Structure at Its Promoter by Song Fan, Tian Tian, Xiaobin Lv, Xinyuan Lei, Zhaohui Yang, Mo Liu, Faya Liang, Shunrong Li, Xiaofeng Lin, Zhaoyu Lin, Shule Xie, Bowen Li, Weixiong Chen, Guokai Pan, Xinyu Lin, Zhanpeng Ou, Yin Zhang, Yu Peng, Liping Xiao, Lizao Zhang, Sheng Sun, Hanqing Zhang, Sigeng Lin, Qunxing Li, Binghui Zeng, Filippos Kontos, Yi Ruan, Soldano Ferrone, Dechen Lin, Bakhos A. Tannous, Jinsong Li

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Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia by Aitana Sogorb-Esteve, Johanna Nilsson, Imogen J. Swift, Carolin Heller, Martina Bocchetta, Lucy L. Russell, Georgia Peakman, Rhian S. Convery, John C. van Swieten, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B. Rowe, Rik Vandenberghe, Elizabeth Finger, Fabrizio Tagliavini, Isabel Santana, Chris R. Butler, Simon Ducharme, Alexander Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Sandro Sorbi, Isabelle Le Ber, Florence Pasquier, Johan Gobom, Ann Brinkmalm, Kaj Blennow, Henrik Zetterberg, Jonathan D. Rohrer, on behalf of the GENetic FTD Initiative

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Case Report: Acquired Disseminated BCG in the Context of a Delayed Immune Reconstitution After Hematological Malignancy by Vincent Gies, Vincent Gies, Vincent Gies, Yannick Dieudonné, Yannick Dieudonné, Florence Morel, Florence Morel, Wladimir Sougakoff, Wladimir Sougakoff, Raphaël Carapito, Raphaël Carapito, Aurélie Martin, Noëlle Weingertner, Léa Jacquel, Léa Jacquel, Fabrice Hubele, Cornelia Kuhnert, Sophie Jung, Sophie Jung, Frederic Schramm, Pierre Boyer, Yves Hansmann, François Danion, Anne-Sophie Korganow, Anne-Sophie Korganow, Aurélien Guffroy, Aurélien Guffroy

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Genetic Aspects and Molecular Testing in Prostate Cancer: A Report from a Dutch Multidisciplinary Consensus Meeting by Niven Mehra, Iris Kloots, Michiel Vlaming, Shafak Aluwini, Els Dewulf, Daniela E. Oprea-Lager, Henk van der Poel, Herman Stoevelaar, Derya Yakar, Chris H. Bangma, Elise Bekers, Roderick van den Bergh, Andries M. Bergman, Franchette van den Berkmortel, Steve Boudewijns, Winand N.M. Dinjens, Jurgen Fütterer, Tom van der Hulle, Guido Jenster, Leonie I. Kroeze, Michel van Kruchten, Geert van Leenders, Pim J. van Leeuwen, Wendy W.J. de Leng, R. Jeroen A. van Moorselaar, Walter Noordzij, Rogier A. Oldenburg, Inge M. van Oort, Irma Oving, Jack A. Schalken, Ivo G. Schoots, Ed Schuuring, Robert J. Smeenk, Ben G.L. Vanneste, Erik Vegt, André N. Vis, Kim de Vries, Peter-Paul M. Willemse, Maurits Wondergem, Margreet Ausems

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IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts by Astrid Van den Eynde, Laura Gehrcken, Tias Verhezen, Ho Wa Lau, Christophe Hermans, Hilde Lambrechts, Tal Flieswasser, Delphine Quatannens, Gils Roex, Karen Zwaenepoel, Elly Marcq, Philippe Joye, Edgar Cardenas De La Hoz, Christophe Deben, Alessia Gasparini, Pierre Montay-Gruel, Maxim Le Compte, Eva Lion, Filip Lardon, Steven Van Laere, Vasiliki Siozopoulou, Diana Campillo-Davo, Jorrit De Waele, Patrick Pauwels, Julie Jacobs, Evelien Smits, Jonas R. M. Van Audenaerde

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Personalized neoantigen-based T cell therapy triggers cytotoxic lymphocytes expressing polyclonal TCR against metastatic ovarian cancer by Shuen-Iu Hung, Mu-Tzu Chu, Ming-Mo Hou, Yun-Shien Lee, Chan-Keng Yang, Sung-Yu Chu, Feng-Yuan Liu, Hung-Chih Hsu, Shih-Cheng Pao, Yu-Chuan Teng, Chun-Bing Chen, Angel Chao, Wen-Hung Chung, John Wen-Cheng Chang, Chyong-Huey Lai

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Impact of the hypoxic microenvironment on spermatogonial stem cells in culture by A. S. Gille, A. S. Gille, A. S. Gille, A. S. Gille, M. Givelet, M. Givelet, M. Givelet, M. Givelet, D. Pehlic, D. Pehlic, C. Lapoujade, C. Lapoujade, B. Lassalle, B. Lassalle, V. Barroca, V. Barroca, A. P. Bemelmans, D. Borderie, D. Borderie, D. Moison, D. Moison, G. Livera, G. Livera, L. R. Gauthier, L. R. Gauthier, F. D. Boussin, F. D. Boussin, N. Thiounn, I. Allemand, I. Allemand, C. Peyssonnaux, C. Peyssonnaux, J. P. Wolf, J. P. Wolf, V. Barraud-Lange, V. Barraud-Lange, L. Riou, L. Riou, P. Fouchet, P. Fouchet

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Association between duration of breastfeeding based on maternal reports and dorsal and ventral striatum and medial orbital gyrus volumes in early adolescence by Daisuke Koshiyama, Naohiro Okada, Shuntaro Ando, Shinsuke Koike, Noriaki Yahata, Kentaro Morita, Kingo Sawada, Susumu Morita, Shintaro Kawakami, Sho Kanata, Shinya Fujikawa, Noriko Sugimoto, Rie Toriyama, Mio Masaoka, Tsuyoshi Araki, Yukiko Kano, Kaori Endo, Syudo Yamasaki, Atsushi Nishida, Mariko Hiraiwa-Hasegawa, Kiyoto Kasai

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Early neurotransmitters changes in prodromal frontotemporal dementia: A GENFI study by Enrico Premi, Marta Pengo, Irene Mattioli, Valentina Cantoni, Juergen Dukart, Roberto Gasparotti, Emanuele Buratti, Alessandro Padovani, Martina Bocchetta, Emily G. Todd, Arabella Bouzigues, David M. Cash, Rhian S. Convery, Lucy L. Russell, Phoebe Foster, David L. Thomas, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Jr, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B. Rowe, Kamen A. Tsvetanov, Rik Vandenberghe, Elizabeth Finger, Pietro Tiraboschi, Alexandre de Mendonça, Isabel Santana, Chris R. Butler, Simon Ducharme, Alexander Gerhard, Johannes Levin, Markus Otto, Sandro Sorbi, Isabelle Le Ber, Florence Pasquier, Jonathan D. Rohrer, Barbara Borroni, Aitana Sogorb Esteve, Carolin Heller, Caroline V. Greaves, Henrik Zetterberg, Imogen J. Swift, Kiran Samra, Rachelle Shafei, Carolyn Timberlake, Thomas Cope, Timothy Rittman, Andrea Arighi, Chiara Fenoglio, Elio Scarpini, Giorgio Fumagalli, Vittoria Borracci, Giacomina Rossi, Giorgio Giaccone, Giuseppe Di Fede, Paola Caroppo, Pietro Tiraboschi, Sara Prioni, Veronica Redaelli, David Tang-Wai, Ekaterina Rogaeva, Miguel Castelo-Branco, Morris Freedman, Ron Keren, Sandra Black, Sara Mitchell, Christen Shoesmith, Robart Bartha, Rosa Rademakers, Jackie Poos, Janne M. Papma, Lucia Giannini, Rick van Minkelen, Yolande Pijnenburg, Benedetta Nacmias, Camilla Ferrari, Cristina Polito, Gemma Lombardi, Valentina Bessi, Michele Veldsman, Christin Andersson, Hakan Thonberg, Linn Öijerstedt, Vesna Jelic, Paul Thompson, Tobias Langheinrich, Albert Lladó, Anna Antonell, Jaume Olives, Mircea Balasa, Nuria Bargalló, Sergi Borrego-Ecija, Ana Verdelho, Carolina Maruta, Catarina B. Ferreira, Gabriel Miltenberger, Frederico Simões do Couto, Alazne Gabilondo, Ana Gorostidi, Jorge Villanua, Marta Cañada, Mikel Tainta, Miren Zulaica, Myriam Barandiaran, Patricia Alves, Benjamin Bender, Carlo Wilke, Lisa Graf, Annick Vogels, Mathieu Vandenbulcke, Philip Van Damme, Rose Bruffaerts, Koen Poesen, Pedro Rosa-Neto, Serge Gauthier, Agnès Camuzat, Alexis Brice, Anne Bertrand, Aurélie Funkiewiez, Daisy Rinaldi, Dario Saracino, Olivier Colliot, Sabrina Sayah, Catharina Prix, Elisabeth Wlasich, Olivia Wagemann, Sandra Loosli, Sonja Schönecker, Tobias Hoegen, Jolina Lombardi, Sarah Anderl-Straub, Adeline Rollin, Gregory Kuchcinski, Maxime Bertoux, Thibaud Lebouvier, Vincent Deramecourt, Beatriz Santiago, Diana Duro, Maria João Leitão, Maria Rosario Almeida, Miguel Tábuas-Pereira, Sónia Afonso

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Differential early subcortical involvement in genetic FTD within the GENFI cohort by Martina Bocchetta, Emily G. Todd, Georgia Peakman, David M. Cash, Rhian S. Convery, Lucy L. Russell, David L. Thomas, Juan Eugenio Iglesias, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B. Rowe, Rik Vandenberghe, Elizabeth Finger, Fabrizio Tagliavini, Alexandre de Mendonça, Isabel Santana, Chris R. Butler, Simon Ducharme, Alexander Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Sandro Sorbi, Isabelle Le Ber, Florence Pasquier, Jonathan D. Rohrer, Sónia Afonso, Maria Rosario Almeida, Sarah Anderl-Straub, Christin Andersson, Anna Antonell, Silvana Archetti, Andrea Arighi, Mircea Balasa, Myriam Barandiaran, Nuria Bargalló, Robart Bartha, Benjamin Bender, Alberto Benussi, Maxime Bertoux, Anne Bertrand, Valentina Bessi, Sandra Black, Sergi Borrego-Ecija, Jose Bras, Alexis Brice, Rose Bruffaerts, Agnès Camuzat, Marta Cañada, Valentina Cantoni, Paola Caroppo, Miguel Castelo-Branco, Olivier Colliot, Thomas Cope, Vincent Deramecourt, María de Arriba, Giuseppe Di Fede, Alina Díez, Diana Duro, Chiara Fenoglio, Camilla Ferrari, Catarina B. Ferreira, Nick Fox, Morris Freedman, Giorgio Fumagalli, Aurélie Funkiewiez, Alazne Gabilondo, Roberto Gasparotti, Serge Gauthier, Stefano Gazzina, Giorgio Giaccone, Ana Gorostidi, Caroline Greaves, Rita Guerreiro, Carolin Heller, Tobias Hoegen, Begoña Indakoetxea, Vesna Jelic, Hans-Otto Karnath, Ron Keren, Gregory Kuchcinski, Tobias Langheinrich, Thibaud Lebouvier, Maria João Leitão, Albert Lladó, Gemma Lombardi, Sandra Loosli, Carolina Maruta, Simon Mead, Lieke Meeter, Gabriel Miltenberger, Rick van Minkelen, Sara Mitchell, Katrina Moore, Benedetta Nacmias, Annabel Nelson, Jennifer Nicholas, Linn Öijerstedt, Jaume Olives, Sebastien Ourselin, Alessandro Padovani, Jessica Panman, Janne M. Papma, Yolande Pijnenburg, Cristina Polito, Enrico Premi, Sara Prioni, Catharina Prix, Rosa Rademakers, Veronica Redaelli, Daisy Rinaldi, Tim Rittman, Ekaterina Rogaeva, Adeline Rollin, Pedro Rosa-Neto, Giacomina Rossi, Martin Rossor, Beatriz Santiago, Dario Saracino, Sabrina Sayah, Elio Scarpini, Sonja Schönecker, Elisa Semler, Rachelle Shafei, Christen Shoesmith, Imogen Swift, Miguel Tábuas-Pereira, Mikel Tainta, Ricardo Taipa, David Tang-Wai, Paul Thompson, Hakan Thonberg, Carolyn Timberlake, Pietro Tiraboschi, Philip Van Damme, Mathieu Vandenbulcke, Michele Veldsman, Ana Verdelho, Jorge Villanua, Jason Warren, Carlo Wilke, Ione Woollacott, Elisabeth Wlasich, Henrik Zetterberg, Miren Zulaica

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Bioresorbable Multilayer Photonic Cavities as Temporary Implants for Tether-Free Measurements of Regional Tissue Temperatures by Wubin Bai, Masahiro Irie, Zhonghe Liu, Haiwen Luan, Daniel Franklin, Khizar Nandoliya, Hexia Guo, Hao Zang, Yang Weng, Di Lu, Di Wu, Yixin Wu, Joseph Song, Mengdi Han, Enming Song, Yiyuan Yang, Xuexian Chen, Hangbo Zhao, Wei Lu, Giuditta Monti, Iwona Stepien, Irawati Kandela, Chad R. Haney, Changsheng Wu, Sang Min Won, Hanjun Ryu, Alina Rwei, Haixu Shen, Jihye Kim, Hong-Joon Yoon, Wei Ouyang, Yihan Liu, Emily Suen, Huang-yu Chen, Jerry Okina, Jushen Liang, Yonggang Huang, Guillermo A. Ameer, Weidong Zhou, John A. Rogers

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CSF glial markers are elevated in a subset of patients with genetic frontotemporal dementia by Ione O. C. Woollacott, Imogen J. Swift, Aitana Sogorb‐Esteve, Carolin Heller, Kathryn Knowles, Arabella Bouzigues, Lucy L. Russell, Georgia Peakman, Caroline V. Greaves, Rhian Convery, Amanda Heslegrave, James B. Rowe, Barbara Borroni, Daniela Galimberti, Pietro Tiraboschi, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Finger, John C. vanSwieten, Harro Seelaar, Lize Jiskoot, Sandro Sorbi, Chris R. Butler, Caroline Graff, Alexander Gerhard, Robert Laforce, Raquel Sanchez‐Valle, Alexandre deMendonça, Fermin Moreno, Matthis Synofzik, Rik Vandenberghe, Simon Ducharme, Isabelle Le Ber, Johannes Levin, Markus Otto, Florence Pasquier, Isabel Santana, Henrik Zetterberg, Jonathan D. Rohrer, the Genetic FTD Initiative, GENFI

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