Detecting overlapping instances in microscopy images using extremal region trees by Arteta, C, Lempitsky, V, Noble, JA, Zisserman, A

“…</p> <p>The model is applied and evaluated over six quite disparate data sets of images covering:&nbsp;fluorescence microscopy, weak-fluorescence molecular images,&nbsp;phase contrast microscopy&nbsp;and&nbsp;histopathology&nbsp;images, and is shown to exceed the state of the art in performance.…”

Nanoparticles prepared from the water extract of Gusuibu (Drynaria fortunei J. Sm.) protects osteoblasts against insults and promotes cell maturation by Hsu C-K, Liao M-H, Tai Y-T, Liu S-H, Ou K-L, Fang H-W, Lee I-J, Chen R-M

“…Chung-King Hsu1,2, Mei-Hsiu Liao3, Yu-Tyng Tai4, Shing-Hwa Liu5, Keng-Liang Ou6, Hsu-Wei Fang7, I-Jung Lee8, Ruei-Ming Chen2,31Institute of Materials Science and Engineering, National Taipei University of Technology, 2Cell Physiology and Molecular Image Research Center, Taipei Medical University-Wan Fang Medical Center, 3Graduate Institute of Medical Sciences, Taipei Medical University, 4Department of Anesthesiology, Taipei Medical University-Wan Fang Medical Center, 5Institute of Toxicology, College of Medicine, National Taiwan University, 6Graduate Institute of Biomedical Materials and Engineering, Taipei Medical University, 7Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, 8Division of Information and Herbarium, National Research Institute of Chinese Medicine, Taipei, TaiwanAbstract: Our previous study showed that Gusuibu (Drynaria fortunei J. …”
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Specificity and Targeting of Optical Molecular Probe FITC-CSPLNTRFC on Breast Cancer Cells Bcap-37 by GUO Chao, ZUO Qi, YANG Xiaofeng, ZHANG Fan

“…The specificity and targeting abilities of FITC-BCSP1 probe for transplantation tumor in Bcap-37 cells tumor-bearing nude mice model were tested by optical molecular imager. Results The purity of the synthesized probe was more than 98%, identified by mass spectrometry and high performance liquid chromatography. …”
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Cholesteric liquid crystal biosensor platform with image analysis for rapid detection of COVID-19 by Ping-Yuan Lin, Yi-Wei Chung, Yi-Wei Chung, Yi-Wei Chung, Yi-Wei Chung, Er-Yuan Chuang, Yen-Chieh Wang, Min-Chih Lai, Yen-Chin Hsu, Chun-Che Lin, Yu-Cheng Hsiao, Yu-Cheng Hsiao, Yu-Cheng Hsiao, Yu-Cheng Hsiao

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Fortification of Iron Oxide as Sustainable Nanoparticles: An Amalgamation with Magnetic/Photo Responsive Cancer Therapies by Rethi L, Rethi L, Liu CH, Hyun TV, Chen CH, Chuang EY

“…Lekha Rethi,1,2,&ast; Lekshmi Rethi,2,&ast; Chia-Hung Liu,3,&ast; Tin Van Hyun,4,5 Chih-Hwa Chen,1,2,6 Er-Yuan Chuang1,2,7 1Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan; 2International PhD Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan; 3Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan; 4International PhD Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan; 5Department of Interventional Cardiology, Thong Nhat Hospital, Ho Chi Minh City, 700000, Vietnam; 6Department of Orthopedics, Taipei Medical University – Shuang Ho Hospital, New Taipei City, Taiwan; 7Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan&ast;These authors contributed equally to this workCorrespondence: Er-Yuan Chuang, Email eychuang@tmu.edu.twAbstract: Due to their non-toxic function in biological systems, Iron oxide NPs (IO-NPs) are very attractive in biomedical applications. …”
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Noninvasively characterizing the different &amp;alpha;v&amp;beta;3 expression patterns in lung cancers with RGD-USPIO using a clinical 3.0T MR scanner by Tao Jiang, Chunfu Zhang, Xuan Zheng, et al

“…Nevertheless, the way of imaging targeting presentation of the probe differed in tumors with different &amp;alpha;v&amp;beta;3 expression patterns.Keywords: USPIO, RGD peptide, &amp;alpha;v&amp;beta;3 integrin, MR molecular imaging…”
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Development of Arteannuin B Sustained-Release Microspheres for Anti-Tumor Therapy by Integrated Experimental and Molecular Modeling Approaches by Yanqing Wang, Weijuan Huang, Nannan Wang, Defang Ouyang, Lifeng Xiao, Sirui Zhang, Xiaozheng Ou, Tingsha He, Rongmin Yu, Liyan Song

“…Moreover, molecular dynamics modeling was firstly used to simulate the preparation process of microspheres, which clearly indicated the molecular image of microspheres and provided in-depth insights for understanding several key preparation parameters. …”
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Antibacterial Pathways in Transition Metal-Based Nanocomposites: A Mechanistic Overview by Mutalik C, Lin IH, Krisnawati DI, Khaerunnisa S, Khafid M, Widodo, Hsiao YC, Kuo TR

“…Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan; 2Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan; 3School of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan; 4Dharma Husada Nursing Academy, Kediri, Indonesia; 5Department of Physiology and Medical Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; 6Department of Nursing, Faculty of Nursing and Midwifery, Universitas Nahdlatul Ulama Surabaya, East Java, Indonesia; 7College of Information System, Universitas Nusantara PGRI, Kediri, Indonesia; 8Graduate Institute of Biomedical Optomechatronics, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan; 9Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; 10Stanford Byers Center for Biodesign, Stanford University, Stanford, CA, USACorrespondence: Yu-Cheng Hsiao; Tsung-Rong Kuo, Tel +886-2-66382736 ext. 1359 ; +886-2-27361661 ext. 7706, Email ychsiao@tmu.edu.tw; trkuo@tmu.edu.twAbstract: Across the planet, outbreaks of bacterial illnesses pose major health risks and raise concerns. …”
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Particle size matters: Discrepancies in the health risks posed by traditional cigarettes and e-cigarettes in mice and humans by Li-Ti Chou, Tsai-Ling Chen, Kai-Chien Yang, Hsiao-Chi Chuang, Ying-Jiun Chen, Ching-Huang Lai, Ta-Chih Hsiao

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Matrix Metalloprotease-7 Mediates Nucleolar Assembly and Intra-nucleolar Cleaving p53 in Gefitinib-Resistant Cancer Stem Cells by Wei-Hsuan Yu, Erxi Wu, Yongqing Li, Hsin-Han Hou, Shuan-su C. Yu, Po-Tsang Huang, Wen-Hung Kuo, Dan Qi, Chong-Jen Yu

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Histology-guided high-resolution AP-SMALDI mass spectrometry imaging of wheat-Fusarium graminearum interaction at the root–shoot junction by Dhaka Ram Bhandari, Qing Wang, Bin Li, Wolfgang Friedt, Andreas Römpp, Bernhard Spengler, Sven Gottwald

“…Histological information was used to identify disease relevant tissues and to assist the interpretation of molecular images. Detected mycotoxin compounds secreted by F. graminearum showed a route of stem infection that was consistent with observations made by microscopy. …”
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Overexpressed Claudin-1 Can Be Visualized Endoscopically in Colonic Adenomas In VivoSummary by Emily F. Rabinsky, Bishnu P. Joshi, Asha Pant, Juan Zhou, Xiyu Duan, Arlene Smith, Rork Kuick, Shuling Fan, Asma Nusrat, Scott R. Owens, Henry D. Appelman, Thomas D. Wang

“…Keywords: Colon Cancer, Early Detection, Molecular Imaging…”
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Air Pollution Effects to the Subtype and Severity of Lung Cancers by Hung-Chi Lee, Hung-Chi Lee, Yueh-Hsun Lu, Yueh-Hsun Lu, Yen-Lin Huang, Yen-Lin Huang, Shih Li Huang, Hsiao-Chi Chuang, Hsiao-Chi Chuang, Hsiao-Chi Chuang

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Therapeutic Potential of Human Umbilical Cord-Derived Mesenchymal Stem Cells in Recovering From Murine Pulmonary Emphysema Under Cigarette Smoke Exposure by Xiao-Yue Chen, Xiao-Yue Chen, Yi-Ying Chen, Willie Lin, Chien-Han Chen, Yu-Chieh Wen, Ta-Chih Hsiao, Hsiu-Chu Chou, Kian Fan Chung, Hsiao-Chi Chuang, Hsiao-Chi Chuang, Hsiao-Chi Chuang

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Blue light at night produces stress-evoked heightened aggression by enhancing brain-derived neurotrophic factor in the basolateral amygdala by Zhenlong Li, Chau-Shoun Lee, Si Chen, Benyu He, Xinya Chen, Hsien-Yu Peng, Tzer-Bin Lin, Ming-Chun Hsieh, Cheng-Yuan Lai, Dylan Chou

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Physiological and Biochemical Effects of Intrinsically High and Low Exercise Capacities Through Multiomics Approaches by Yu-Tang Tung, Yu-Tang Tung, Yu-Tang Tung, Yi-Ju Hsu, Chen-Chung Liao, Shang-Tse Ho, Chi-Chang Huang, Chi-Chang Huang, Wen-Ching Huang

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Dysregulation of the miR-25-IMPA2 axis promotes metastatic progression in clear cell renal cell carcinomaResearch in context by Yuh-Feng Lin, Jian-Liang Chou, Jeng-Shou Chang, I-Jen Chiu, Hui-Wen Chiu, Yuan-Feng Lin

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Downregulation of TAZ elicits a mitochondrial redox imbalance and ferroptosis in lung epithelial cells exposed to diesel exhaust particles by Kang-Yun Lee, Ching-Chieh Yang, Pei-Wei Shueng, Sheng-Min Wu, Chih-Hsuan Chen, Yi-Chun Chao, Yu-Chu Chang, Chia-Li Han, Hsiao-Chi Chuang, Chi-Ching Lee, Cheng-Wei Lin

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Near-infrared-driven photoablation of lung cancer tumors utilizing biomimetic platelet-polyethyleneimine-polypyrrole drug-free nanoparticles by Thierry Burnouf, Pei-Ru Jheng, Yun-Hsuan Chen, Lekshmi Rethi, Lekha Rethi, Long-Sheng Lu, Yi-Cheng Ho, Er-Yuan Chuang

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Effects of dietary adjustment of n-3:n-6 fatty-acid ratio to 1:2 on anti-inflammatory and insulin-signaling pathways in ovariectomized mice with high fat diet-induced obesity by Yu-Tang Tung, Ya-Ling Chen, Tzu-Yu Fan, Tsorng-Harn Fong, Wan-Chun Chiu

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