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141
Molecular mechanism of human anti-Zika non-structural protein 1 antibodies
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Final Year Project (FYP) -
142
Functional analysis of molecular mechanisms associated with invasion of erythrocytes by human malaria parasite.
Published 2011“…The main objective of this project is to explore methods of high throughput functional genomics to analyze molecular mechanisms associated with the invasion machinery by which the human malaria parasites Plasmodium falciparum invade its host erythrocytes. …”
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Research Report -
143
Molecular mechanisms of selection pressure-driven aerobic granulation in sequencing batch reactors
Published 2013“…Big, round-shape, and dense aerobic granules can be developed at a short settling time or a high hydrodynamic shear force. However, the molecular mechanisms of aerobic granulation driven by selection pressure remain unclear. …”
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Thesis -
144
Quantum hessian fitting for quick determination of force constant parameters in molecular mechanics
Published 2017“…We present three new methods called Full, Partial, and Internal Hessian Fitting (FHF, PHF, and IHF) for deriving force constant parameters that are used in molecular mechanics (MM) force fields to describe the bond-stretching, angle-bending, dihedral-torsion, and improper-torsion terms. …”
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Thesis -
145
Molecular mechanisms of premature ageing in a worm model of human Werner syndrome
Published 2014Thesis -
146
Molecular mechanisms of ADAM17 regulation by iRhom2 in cell signalling
Published 2022“…<p>The rhomboid-like protein iRhom2 is an essential regulator of ADAM17, a metalloprotease that cleaves and releases vital signalling molecules involved in many processes including inflammatory diseases and cancer. However, the molecular mechanisms of ADAM17 activation by iRhom2, and the links between iRhom2 and cancer, are unclear. …”
Thesis -
147
Diverse molecular mechanisms involved in AChR deficiency due to rapsyn mutations
Published 2006Journal article -
148
The ParMRC system: molecular mechanisms of plasmid segregation by actin-like filaments.
Published 2010“…In this Review, we look at some of the most exciting questions in the field concerning the exact molecular mechanisms by which the components of this self-contained system modulate one another's activity to achieve bipolar DNA segregation.…”
Journal article -
149
Molecular mechanisms of hedgehog signal transduction by the G-protein coupled receptor smoothened
Published 2017“…In this thesis, I present my work into the structural and functional characterisation of the extracellular and transmembrane domains (TMD) of human SMO in order to better understand the molecular mechanisms of its signal transduction. The extracellular region of SMO contains a highly conserved cysteine-rich domain (CRD) and a linker domain (LD). …”
Thesis -
150
Translating genetic association signals for diabetes and metabolic traits into molecular mechanisms for disease
Published 2014Journal article -
151
The evolution of antibiotic resistance: insight into the roles of molecular mechanisms of resistance and treatment context.
Published 2010Journal article -
152
Molecular-mechanics study of oligomeric models for poly(ferrocenylsilanes) using the ESFF forcefield
Published 1996Journal article -
153
Bridging the gap between genetic associations and molecular mechanisms for type 2 diabetes.
Published 2013Journal article -
154
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Published 2018Journal article -
155
Molecular mechanisms underlying WOX1 activation during apoptotic and stress responses.
Published 2003Journal article -
156
FLT3 overexpression in acute leukaemias: new insights into the search for molecular mechanisms
Published 2019“…This transcriptional deregulation is important to define the prognostic risk for many patients. Of note, the molecular mechanisms leading to this gene upregulation are unknown for a substantial number of cases. …”
Journal article -
157
A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds
Published 2018Journal article -
158
Diverse molecular mechanisms involved in AChR deficiency due to rapsyn mutations.
Published 2006Journal article -
159
Structure and molecular mechanism of a nucleobase-cation-symport-1 family transporter.
Published 2008Journal article -
160