Location, location, location: how the tissue microenvironment affects inflammation in RA by Buckley, CD, Ospelt, C, Gay, S, Midwood, KS

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Molecular medicine: a path towards a personalized medicine Medicina molecular: um passo em direção à medicina personalizada by Debora Marques de Miranda, Marcelo Mamede, Bruno Rezende de Souza, Alexandre Guimarães de Almeida Barros, Luiz Alexandre Magno, Antônio Alvim-Soares Jr, Daniela Valadão Rosa, Célio José de Castro Jr, Leandro Malloy-Diniz, Marcus Vinícius Gomez, Luiz Armando De Marco, Humberto Correa, Marco Aurélio Romano-Silva

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HerbKG: Constructing a Herbal-Molecular Medicine Knowledge Graph Using a Two-Stage Framework Based on Deep Transfer Learning by Xian Zhu, Xian Zhu, Yueming Gu, Zhifeng Xiao

“…Existing knowledge graphs in herbalism mainly focus on diagnosis and treatment with an absence of knowledge connection with molecular medicine. To fill this gap, we present HerbKG, a knowledge graph that bridges herbal and molecular medicine. …”
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Time to Change Theory; Medical Leech from a Molecular Medicine Perspective Leech Salivary Proteins Playing a Potential Role in Medicine by Amir Shakouri, Uwe Wollina

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Erythropoietin mediates brain-vascular-kidney crosstalk and may be a treatment target for pulmonary and resistant essential hypertension by Emine Meltem Onal, Alan Alper Sag, Oguzhan Sal, Aslihan Yerlikaya, Baris Afsar, Mehmet Kanbay

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A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling by Jason A. Hackney, Haridha Shivram, Jason Vander Heiden, Chris Overall, Luz Orozco, Xia Gao, Eugene Kim, Nathan West, Aditi Qamra, Diana Chang, Arindam Chakrabarti, David F. Choy, Alexis J. Combes, Tristan Courau, Gabriela K. Fragiadakis, Arjun Arkal Rao, Arja Ray, Jessica Tsui, Kenneth Hu, Nicholas F. Kuhn, Matthew F. Krummel, David J. Erle, Kirsten Kangelaris, Aartik Sarma, Zoe Lyon, Carolyn S. Calfee, Prescott G. Woodruff, Rajani Ghale, Eran Mick, Ashley Byrne, Beth Shoshana Zha, Charles Langelier, Carolyn M. Hendrickson, Monique G.P. van der Wijst, George C. Hartoularos, Tianna Grant, Raymund Bueno, David S. Lee, John R. Greenland, Yang Sun, Richard Perez, Anton Ogorodnikov, Alyssa Ward, Chun Jimmie Ye, Thiru Ramalingam, Jacqueline M. McBride, Fang Cai, Anastasia Teterina, Min Bao, Larry Tsai, Ivan O. Rosas, Aviv Regev, Sharookh B. Kapadia, Rebecca N. Bauer, Carrie M. Rosenberger, Yumiko Abe-Jones, Michael Adkisson, K. Mark Ansel, Saurabh Asthana, Alexander Beagle, Sharvari Bhide, Cathy Cai, Saharai Caldera, Maria Calvo, Sidney A. Carrillo, Suzanna Chak, Stephanie Christenson, Zachary Collins, Spyros Darmanis, Angela Detweiler, Catherine DeVoe, Walter Eckalbar, Jeremy Giberson, Ana Gonzalez, Gracie Gordon, Paula Hayakawa Serpa, Alejandra Jauregui, Chayse Jones, Serena Ke, Divya Kushnoor, Tasha Lea, Deanna Lee, Aleksandra Leligdowicz, Yale Liu, Salman Mahboob, Lenka Maliskova, Michael Matthay, Elizabeth McCarthy, Priscila Muñoz-Sandoval, Norma Neff, Viet Nguyen, Nishita Nigam, Randy Parada, Maira Phelps, Logan Pierce, Priya Prasad, Sadeed Rashid, Gabriella Reeder, Nicklaus Rodriguez, Bushra Samad, Andrew Schroeder, Cole Shaw, Alan Shen, Austin Sigman, Pratik Sinha, Matthew Spitzer, Sara Sunshine, Kevin Tang, Luz Torres Altamirano, Alexandra Tsitsiklis, Erden Tumurbaatar, Vaibhav Upadhyay, Alexander Whatley, Andrew Willmore, Michael Wilson, Juliane Winkler, Kristine Wong, Kimberly Yee, Michelle Yu, Mingyue Zhou, Wandi S. Zhu

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Culin5 aggravates hypoxic pulmonary hypertension by activating TRAF6/NF-κB/HIF-1α/VEGF by Lei Wang, Jing Huang, Ruoyang Zhang, Muzhi Zhang, Yu Guo, Yang Liu, Cong Li, Wei Wang, Sun Ying, Jie Liu, Chen Wang

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Gastric cancer: current and evolving treatment landscape by Weijing Sun, Li Yan

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LncRNA CFRL aggravates cardiac fibrosis by modulating both miR-3113-5p/CTGF and miR-3473d/FN1 axis by Yue Cui, Bozhong Shi, Zijie Zhou, Bo Chen, Xiaoyang Zhang, Cong Li, Kai Luo, Zhongqun Zhu, Jinghao Zheng, Xiaomin He

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Molecular Classification of Colorectal Cancers and Clinical Application by So Yeon Jeon, Won Kyu Kim, Hoguen Kim

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Combined effects of double mutations on catalytic activity and structural stability contribute to clinical manifestations of glucose-6-phosphate dehydrogenase deficiency by Pakparnich, P, Sudsumrit, S, Imwong, M, Suteewong, T, Chamchoy, K, Pakotiprapha, D, Leartsakulpanich, U, Boonyuen, U

Subjects: “…Molecular medicine…”

Intervening along the spectrum of tuberculosis: meeting report from the World TB Day nanosymposium in the Institute of Infectious Disease and Molecular Medicine at the University of Cape Town by Hadebe, Sabelo, Chengalroyen, Melissa, Guler, Reto, Nakedi, Kehilwe, Koch, Anastasia, Makatsa, Mohau, Shey, Muki, Parihar, Suraj P, Bryson, Bryan, Marakalala, Mohlopheni J, Ndlovu, Hlumani

“…It is within this backdrop that we convened a nanosymposium at the Institute of Infectious Disease and Molecular Medicine at the University of Cape Town to commemorate World TB Day and showcase recent findings generated by early career scientists in the institute. …”
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Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia by Xinya Jiang, Kexiu Huang, Xiaofan Sun, Yue Li, Lei Hua, Fangshu Liu, Rui Huang, Juan Du, Hui Zeng

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HOW THE MULTIFUNCTIONAL NANOCARRIER MAKES THE MEDICINE «SMART»? by Rostyslav Stoika

Subjects: “…pharmacology, molecular medicine, nanotechnology, cancerogenesis, drug-resistance…”
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Wnt antagonism without TGFβ induces rapid MSC chondrogenesis via increasing AJ interactions and restricting lineage commitment by Chen-Chan Hsieh, B. Linju Yen, Chia-Chi Chang, Pei-Ju Hsu, Yu-Wei Lee, Men-Luh Yen, Shaw-Fang Yet, Linyi Chen

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Activation of GDNF-ERK-Runx1 signaling contributes to P2X3R gene transcription and bone cancer pain by Zhu-Lin Yuan, Xiao-Dan Liu, Zi-Xian Zhang, Song Li, Yue Tian, Ke Xi, Jie Cai, Xiao-Mei Yang, Min Liu, Guo-Gang Xing

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Combined effect of D-dimer, hs-CRP, and Lp(a) on 5-year clinical outcomes after percutaneous coronary intervention: A large real-world study in China by Jiawen Li, Pei Zhu, Xiaofang Tang, Lin Jiang, Yulong Li, Kailun Yan, Weixian Yang, Shubin Qiao, Yuejin Yang, Runlin Gao, Bo Xu, Jinqing Yuan, Xueyan Zhao

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A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases by Gawel, Danuta R., Serra-Musach, Jordi, Lilja, Sandra, Aagesen, Jesper, Arenas, Alex, Asking, Bengt, Bengnér, Malin, Björkander, Janne, Biggs, Sophie, Ernerudh, Jan, Hjortswang, Henrik, Karlsson, Jan-Erik, Köpsen, Mattias, Lee, Eun Jung, Lentini, Antonio, Li, Xinxiu, Magnusson, Mattias, Martínez-Enguita, David, Matussek, Andreas, Nestor, Colm E., Schäfer, Samuel, Seifert, Oliver, Sonmez, Ceylan, Stjernman, Henrik, Tjärnberg, Andreas, Wu, Simon, Åkesson, Karin, Shalek, Alexander K, Stenmarker, Margaretha, Zhang, Huan, Gustafsson, Mika, Benson, Mikael

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The ischaemic preconditioning paradox and its implications for islet isolation from heart-beating and non heart-beating donors by Brandhorst, D, Brandhorst, H, Acreman, S, Johnson, PRV

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A tubulin binding molecule drives differentiation of acute myeloid leukemia cells by Thomas R. Jackson, Aini Vuorinen, Laia Josa-Culleré, Katrina S. Madden, Daniel Conole, Thomas J. Cogswell, Isabel V.L. Wilkinson, Laura M. Kettyle, Douzi Zhang, Alison O’Mahony, Deanne Gracias, Lorna McCall, Robert Westwood, Georg C. Terstappen, Stephen G. Davies, Edward W. Tate, Graham M. Wynne, Paresh Vyas, Angela J. Russell, Thomas A. Milne

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