Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells. by Xue, L, Salimi, M, Panse, I, Mjösberg, J, McKenzie, A, Spits, H, Klenerman, P, Ogg, G

“…Chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2), a receptor for prostaglandin D₂ (PGD₂), is expressed by human ILC2s. …”

Biphenyl ether analogs containing pomalidomide as small-molecule inhibitors of the programmed cell death-1/programmed cell death-ligand 1 interaction by Shaabani, S, Gadina, L, Surmiak, E, Wang, Z, Zhang, B, Butera, R, Zarganis-Tzitzikas, T, Rodriguez, I, Kocik-Krol, J, Magiera-Mularz, K, Skalniak, L, Dömling, A, Holak, TA

REDOX-ACTIVE CAVITAND HOST MOLECULES CONTAINING MULTIPLE FERROCENYL REDOX CENTERS - SYNTHESES, CRYSTAL-STRUCTURE, MOLECULAR MECHANICS CALCULATIONS, AND ELECTROCHEMICAL PROPERTIES by Beer, P, Tite, E, Drew, M, Ibbotson, A

“…The design, synthesis, X-ray crystal structure, molecular mechanics calculations, and electrochemical properties of novel redox-active cavitand host molecules containing multiple ferrocenyl redox centres are described. …”

Small molecule CD38 inhibitors: synthesis of 8-amino-N1-inosine 5'-monophosphate, analogues and early structure-activity relationship by Watt, J, Graeff, R, Potter, B

“…Although a monoclonal antibody targeting the multifunctional ectoenzyme CD38 is an FDA approved drug, few small molecule inhibitors exist for this enzyme that catalyzes inter alia the formation and metabolism of the N1-ribosylated, Ca2+ -mobilizing, second messenger cyclic adenosine 5'-diphosphoribose (cADPR). …”

Development of a tissue array for primary melanoma with long-term follow-up: discovering melanoma cell adhesion molecule as an important prognostic marker. by Pacifico, MD, Grover, R, Richman, P, Daley, F, Buffa, F, Wilson, G

“…This was sectioned and stained for the adhesion marker melanoma cell adhesion molecule (MCAM); after further review, 76 of the 120 specimens were suitable for further analysis. …”

CD24, a signal-transducing molecule expressed on human B cells, is a major surface antigen on small cell lung carcinomas. by Jackson, D, Waibel, R, Weber, E, Bell, J, Stahel, R

“…The sequence of the cluster-w4 complementary DNA encodes an unusually short (80-amino acid) protein identical to that recently reported for the leukocyte activation molecule CD24 except for a single valine-alanine substitution due to a single-base polymorphism within the region of the gene coding for the extracellular domain. …”

An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration. by Turner, G, Morrison, H, Jones, M, Davis, T, Looareesuwan, S, Buley, I, Gatter, K, Newbold, C, Pukritayakamee, S, Nagachinta, B

“…This process is mediated by specific interactions between parasite adherence ligands and host receptors on vascular endothelium such as intercellular adhesion molecule-1 (ICAM-1) and CD36. Using immunohistochemistry we have examined the distribution of putative sequestration receptors in different organs from fatal cases of P. falciparum malaria and noninfected controls. …”

IN-VIVO MAGNETIC RESONANCE IMAGING OF RENAL ISCHAEMIA/REPERFUSION INJURY USING MICROPARTICLES OF IRON OXIDE TARGETING VASCULAR CELL ADHESION MOLECULE 1 by Akhtar, A, Schneider, J, McAteer, M, Chapman, S, Barnes, H, Digby, J, Wood, K, Choudhury, R

Stability of empty and peptide-loaded class II major histocompatibility complex molecules at neutral and endosomal pH: comparison to class I proteins. by Reich, Z, Altman, J, Boniface, J, Lyons, D, Kozono, H, Ogg, G, Morgan, C, Davis, M

“…The structure and thermal stability of empty and peptide-filled forms of the murine class II major histocompatibility complex (MHC) molecule I-E(k) were studied at neutral and mildly acidic pH. …”

Infrared signature of structural isomers of gas– phase M+(N2O)n(M = Cu, Ag, Au) ion–molecule complexes by Cunningham, E, Gentleman, A, Beardsmore, P, Iskra, A, Mackenzie, S

Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells by Xue, L, Salimi, M, Panse, I, Mjösberg, J, McKenzie, A, Spits, H, Klenerman, P, Ogg, G

“…Chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), a receptor for prostaglandin D2 (PGD2), is expressed in human ILC2. …”

HD6: A NOVEL MONOCLONAL ANTIBODY THAT RECOGNISES A SUBSET OF HLA-B27 MOLECULES STRONGLY IMPLICATED IN SPONDYLOARTHRITIS DISEASE PATHOGENESIS by McHugh, K, Giles, J, Shaw, J, Kollnberger, S, Payeli, S, Utriainen, L, Milling, S, Renner, C, Bowness, P

Alkali metal cation cooperative iodide anion recognition by new heteroditopic bis(calix[4]arene) rhenium(I) bipyridyl receptor molecules by Beer, P, Cooper, J

Local magnetism in the molecule-based metamagnet [Ru-2(O2CMe)(4)](3)[Cr(CN)(6)] probed with implanted muons by Lancaster, T, Pratt, F, Blundell, S, Steele, A, Baker, P, Wright, J, Watanabe, I, Fishman, R, Miller, J

“…We present a muon-spin relaxation study of local magnetism in the molecule-based metamagnet [Ru2(O2CMe)4] 3[Cr(CN)6]. …”

REDOX-ACTIVE CAVITAND HOST MOLECULES CONTAINING MULTIPLE REDOX CENTERS, SYNTHESES AND X-RAY CRYSTAL-STRUCTURE OF A DICHLOROMETHANE INCLUSION COMPLEX by Beer, P, Drew, M, Ibbotson, A, Tite, E

“…The synthesis and electrochemistry of two novel redox-active rigid cavitand hydrophobic host molecules (4) and (7), both containing four ferrocene moieties, are reported; the single crystal X-ray structure of (4) reveals a dichloromethane guest molecule within the cavitand host cavity.…”

A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models by Zarghami, N, Soto, MS, Perez-Balderas, F, Khrapitchev, AA, Karali, CS, Johanssen, VA, Ansorge, O, Larkin, JR, Sibson, NR

“…Upregulation of endothelial ALCAM (activated leukocyte cell adhesion molecule) is a key element for leukocyte recruitment in neurological disease. …”

Electron paramagnetic resonance studies of the high-spin molecule Cr-10(OMe)(20)(O2CCMe3)(10) - art. no. 03250 by Sharmin, S, Ardavan, A, Blundell, S, Coldea, A, McInnes, E, Low, D

Noninvasive Molecular Imaging of Differential Endothelial Adhesion Molecule Expression in Early Atherosclerosis Correlates With Plaque Macrophage Content in Apo E Knockout Mice by McAteer, M, Mankia, K, Hagen, R, Stork, L, Schneider, J, Choudhury, R

SYNTHESIS AND X-RAY CRYSTAL-STRUCTURE OF A NEW REDOX-ACTIVE CALIX[5]ARENE CONTAINING A TOTALLY INCLUDED ETHANOL MOLECULE by Beer, P, Chen, Z, Drew, M, Gale, P

“…A novel p-tert-butylcalix[5]arene trisferrocenoyl ester molecule L has been prepared; the X-ray crystal structure of the ethanol complex of L reveals the guest molecule bound deep in the cavity of the calix[5]arene.…”

Probe-molecule-assisted NMR spectroscopy: A comparison with photoluminescence and electron paramagnetic resonance spectroscopy as a characterization tool in facet-specific photocatalysis by Peng, Y, Fu, Y, Zhang, L, Teixeira, I, Ye, L, He, H, Tsang, S

“…Here, we used the chemical adsorption of a 31 P-containing probe molecule to obtain the distribution/concentration of V O surface as well as other surface features (hydroxyl groups) of ZnO by using 31 P magic-angle spinning NMR spectroscopy. …”