Molecular occupancy of nanodot arrays by Cai, H, Wolfenson, H, Depoil, D, Dustin, M, Sheetz, M, Wind, S

“…As an example, the nanoarray platform was used to probe the geometric requirement of T-cell activation at the single-molecule level.…”

DNA and lipid bilayers: self-assembly and insertion. by Khalid, S, Bond, P, Holyoake, J, Hawtin, R, Sansom, MS

“…Local bilayer deformation in the vicinity of the DNA molecule is observed, largely as a result of the DNA-DMTAP headgroup attraction.…”

Detecting protein analytes that modulate transmembrane movement of a polymer chain within a single protein pore. by Movileanu, L, Howorka, S, Braha, O, Bayley, H

“…Accordingly, the modified pore allows detection of a protein analyte at the single-molecule level, facilitating both quantification and identification through a distinctive current signature. …”

Quantitative mass imaging of single biological macromolecules by Young, G, Hundt, N, Cole, D, Fineberg, A, Andrecka, J, Tyler, A, Olerinyova, A, Ansari, A, Marklund, EG, Collier, MP, Chandler, SA, Tkachenko, O, Allen, J, Crispin, M, Billington, N, Takagi, Y, Sellers, JR, Eichmann, C, Selenko, P, Frey, L, Riek, R, Galpin, MR, Struwe, WB, Benesch, JLP, Kukura, P

“…We resolved oligomeric distributions at high dynamic range, detected small-molecule binding, and mass-imaged proteins with associated lipids and sugars. …”

High-resolution microwave studies of ring-structured complexes between trifluoroacetic acid and water. by Ouyang, B, Starkey, T, Howard, B

“…The rotational spectra of the complexes between one trifluoroacetic acid molecule and up to three water molecules have been recorded using a pulsed nozzle Fourier transform microwave spectrometer. …”

PREDICTION OF THE SPECTRUM FOR EXCITATION OF THE VANDERWAALS MODES IN ARHCN by Clary, D, Dateo, C, Stoecklin, T

“…These low frequency bending modes arise from the small rotational constant of the HCN molecule and are not due to special features of the Ar-HCN potential energy surface. © 1990 American Institute of Physics.…”

Bacterial flagellar motor. by Sowa, Y, Berry, R

“…This review outlines what has been learned about the structure and function of the motor using a combination of genetics, single-molecule and biophysical techniques, with a focus on recent results and single-molecule techniques.…”

Side-impact collisions of Ar with NO by Heid, C, Walpole, V, Brouard, M, Jambrina, P, Aoiz, F

“…This may involve directed end-on collisions along a molecular bond axis or encounters in which the partner approaches the bond of an oriented molecule from the side. Using both experiment and theory, we show here that in the simplest case of an inelastic collision between an atom and a nearly homonuclear diatom, in which the two atoms have almost the same mass, the scattering dynamics are very distinct for impacts on either side of the molecule. …”

Electrospray ion beam deposition plus low-energy electron holography as a tool for imaging individual biomolecules by Ochner, H, Rauschenbach, S, Malavolti, L

“…Inline low-energy electron holography (LEEH) in conjunction with sample preparation by electrospray ion beam deposition (ES-IBD) has recently emerged as a promising method for the sub-nanometre-scale single-molecule imaging of biomolecules. The single-molecule nature of the LEEH measurement allows for the mapping of the molecules' conformational space and thus for the imaging of structurally variable biomolecules, thereby providing valuable complementary information to well-established biomolecular structure determination methods. …”

The crystal structure of H-2D(b) complexed with a partial peptide epitope suggests a major histocompatibility complex class I assembly intermediate. by Glithero, A, Tormo, J, Doering, K, Kojima, M, Jones, E, Elliott, T

“…We have crystallized the complex of the H-2D(b) molecule with the pentamer and determined the structure to show how a quasi-stable MHC class I molecule can be formed by occupancy of a single binding pocket in the peptide-binding groove.…”

Light controlled optical Aharonov–Bohm oscillations in a single quantum ring by Kim, H, Park, S, Okuyama, R, Kyhm, K, Eto, M, Taylor, R, Nogues, G, Dang, L, Potemski, M, Je, K, Kim, J, Kyhm, J, Song, J

“…With a weak excitation intensity of 1.2 kW cm–2, the optical Aharonov–Bohm oscillation period of biexcitons was observed to be half that of excitons in accordance with the period expected for a two-exciton Wigner molecule. When the excitation intensity is increased by an order of magnitude (12 kW cm–2), a gradual deviation of the Wigner molecule condition occurs with decreased oscillation periods and diamagnetic coefficients for both excitons and biexcitons along with a spectral shift. …”

Far-field electrostatic signatures of macromolecular 3D conformation by Kloes, G, Bennett, TJD, Chapet-Batlle, A, Behjatian, A, Turberfield, AJ, Krishnan, M

“…For instance, a tetrahedral structure, which is the most compact distribution of charge we tested, can create a far-field effect that is effectively identical to that of a rod-shaped molecule carrying half the amount of total structural charge. …”

Label-free imaging of microtubules with sub-nm precision using interferometric scattering microscopy by Andrecka, J, Arroyo, J, Lewis, K, Cross, R, Kukura, P

“…The ability of iSCAT to track microtubules with nm precision together with its potential for label-free single protein detection and simultaneous single molecule fluorescence imaging represent a unique platform for novel approaches to studying microtubule dynamics.…”

Characterizing the multi-dimensional reaction dynamics of dihalomethanes using XUV-induced Coulomb explosion imaging by Walmsley, T, Unwin, J, Allum, F, Bari, S, Boll, R, Brouard, M, Borne, K, Bucksbaum, P, Ekanayake, N, Erk, B, Forbes, R, Howard, AJ, Eng-Johnsson, P, Lee, JWL, Liu, Z, Manschwetus, B, Mason, R, Passow, C, Peschel, J, Rivas, D, Rolles, D, Rörig, A, Rouzée, A, Vallance, C, Ziaee, F, Burt, M

“…Time-dependent fragment ion momenta were recorded using Coulomb explosion imaging mass spectrometry and used to determine the structural dynamics of the dissociating molecules. Correlations between these fragment momenta, as well as the onset times of electron transfer reactions between them, indicate that each molecule can undergo neutral three-body photolysis. …”

Mouse H-2(k)-restricted cytotoxic T cells recognize antigenic determinants in both the HA1 and HA2 subunits of the influenza A/PR/8/34 hemagglutinin by Gould, K, Scotney, H, Townsend, A, Bastin, J, Brownlee, G

“…We have constructed two chimeric influenza hemagglutinin (HA) genes in which the HA1 and HA2 subunits of the HA molecule have been interchanged between influenza A/PR/8/34 (H1 subtype) and A/NT/60/68 (H3 subtype). …”

Gauging the flexibility of fluorescent markers for the interpretation of fluorescence resonance energy transfer. by Rindermann, J, Akhtman, Y, Richardson, J, Brown, T, Lagoudakis, P

“…The major uncertainty originates from the unknown orientation between the optical dipole moments of the fluorescent markers, especially when the molecule undergoes thermal fluctuations in physiological conditions. …”

Topology of electron density of cadmium telluride determined from relief and contour plots by Othman, A.P., Gopir, G.A.

“…These bond paths indicated that the molecule was slightly covalent. Our topological analysis led us to conclude that CdTe was an n-type semiconductor with covalent bond and slight ionic character.…”
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Bis[N `-(2-oxo-1H-indol-3-ylidene)furan2-carbohydrazidato-kappa O-3,N `,O `]manganese(II) N,N-dimethylformide monosolvate monohydrate by Halim, S.N.A., Ali, H.M., Ng, S.W.

“…The N-H groups, the carbonyl group of the DMF molecule and the uncoordinated water molecule engage in N-H center dot center dot center dot O and O-H center dot center dot center dot O hydrogen-bonding interactions, generating a hydrogen-bonded ribbon that propagates along [110].…”

Bis[N `-(2-oxo-1H-indol-3-ylidene)thiophene-2-carbohydrazidato-kappa O-3,N `,O `]zinc(II) N,N-dimethylformide monosolvate monohydrate by Halim, S.N.A., Ali, H.M., Ng, S.W.

“…The N-H groups of the ligands, the carbonyl group of the DMF molecule and uncoordinated water molecule engage in N-H center dot center dot center dot O and O-H center dot center dot center dot O interactions, generating a hydrogen-bonded ribbon that propagates along [110]. …”

Di-mu-nicotinato-kappa N-2/O;kappa O-2/N-bis[aquabis(4-bromobenzyl)(nicotinato-kappa O-2,O `)tin(IV)] by Keng, C.T., Lo, K.M., Ng, S.W.

“…Two nicotinate binding modes are observed in the dinuclear title compound, [Sn-2(C7H6Br)(4)(C6H4NO2)(4)(H2O)(2)]: in the first, a terminal O,O'-chelating molecule binds to a water-coordinated diorganotin cation, while the second mode corresponds to an O:N-bridging molecule which binds to two cations. …”