LIR motif-containing hyperdisulfide β-ginkgotide is cytoprotective, adaptogenic, and scaffold-ready by Dutta, Bamaprasad, Huang, Jiayi, To, Janet, Tam, James P.

“…The ginkgo plant-derived β-ginkgotide β-gB1 is a highly unusual molecule: Small, hyperdisulfide, and found only in selected ancient plants. …”
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Tuning Model Drug Release and Soft-Tissue Bioadhesion of Polyester Films by Plasma Post-Treatment by Mogal, Vishal T., Yin, Chaw Su, O’Rorke, Richard, Boujday, Souhir, Méthivier, Christophe, Venkatraman, Subbu S., Steele, Terry W. J.

“…In vitro release of the drug-like molecule fluorescein diacetate (FDAc) from plasma-treated PLGA was tunable by controlling RF power; an increase of 65% cumulative release is reported compared to controls. …”
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Novel Photochrome Aptamer Switch Assay (PHASA) for Adaptive Binding to Aptamers by Papper, Vladislav, Pokholenko, Oleksandr, Wu, Yuanyuan, Zhou, Yubin, Ping, Jianfeng, Steele, Terry W. J., Marks, Robert S.

“…A unique feature of the stilbene molecule is its reporting power via trans-cis photoisomerisation (from fluorescent trans-isomer to non-fluorescent cis-isomer) upon irradiation with the excitation light. …”
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Elastic Light Tunable Tissue Adhesive Dendrimers by Feng, Gao, Djordjevic, Ivan, Mogal, Vishal, O'Rorke, Richard, Pokholenko, Oleksandr, Steele, Terry W. J.

“…This particular diazirine molecule can be grafted to the surface amine groups of PAMAM in a one-pot synthesis. …”
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RpoN Regulates Virulence Factors of Pseudomonas aeruginosa via Modulating the PqsR Quorum Sensing Regulator by Cai, Zhao, Liu, Yang, Chen, Yicai, Yam, Joey Kuok Hoong, Chew, Su Chuen, Chua, Song Lin, Wang, Ke, Givskov, Michael, Yang, Liang

“…The ∆rpoN mutant is able to synthesize 4-quinolone signal molecule HHQ but unable to activate PqsR and Pseudomonas quinolone signal (pqs) quorum sensing. …”
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pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion by Iovino, Federico, Engelen-Lee, Joo-Yeon, Brouwer, Matthijs, van de Beek, Diederik, van der Ende, Arie, Valls Seron, Merche, Mellroth, Peter, Muschiol, Sandra, Bergstrand, Jan, Widengren, Jerker, Henriques-Normark, Birgitta

“…Using stimulated emission depletion (STED) super-resolution microscopy of brain biopsies from patients who died of pneumococcal meningitis, we observe that pneumococci colocalize with the two BBB endothelial receptors: polymeric immunoglobulin receptor (pIgR) and platelet endothelial cell adhesion molecule (PECAM-1). We show that the major adhesin of the pneumococcal pilus-1, RrgA, binds both receptors, whereas the choline binding protein PspC binds, but to a lower extent, only pIgR. …”
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Precision oncology : oncogenic stat3 signalling in brain tumours by Tan, Melanie Si Yan

“…Furthermore, there are several STAT3 small molecule inhibitors in clinical trials for solid malignancies. …”
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Ultralong Phosphorescence of Water-Soluble Organic Nanoparticles for In Vivo Afterglow Imaging by Zhen, Xu, Tao, Ye, An, Zhongfu, Chen, Peng, Xu, Chenjie, Chen, Runfeng, Huang, Wei, Pu, Kanyi

“…This study not only introduces the first category of water-soluble ultralong phosphorescence organic nanoparticles but also reveals a universal design principle to prolong the lifetime of phosphorescent molecules to the level that can be effective for molecular imaging.…”
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Ultrasensitive optical microfiber coupler based sensors operating near the turning point of effective group index difference by Zhang, Nan, Li, Kaiwei, Zhang, Ting, Liu, Guigen, Zhang, Mengying, Wei, Lei

“…The resulting ultrasensitive RI sensing platform offers a substantial impact on a variety of applications from high performance trace analyte detection to small molecule sensing.…”
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Perovskite templating via a bathophenanthroline additive for efficient light-emitting devices by Jamaludin, Nur Fadilah, Yantara, Natalia, Ng, Yan Fong, Bruno, Annalisa, Chandran, Bevita K., Chin, Xin Yu, Thirumal, Krishnamoorthy, Mathews, Nripan, Soci, Cesare, Mhaisalkar, Subodh

“…Herein, it is shown that by incorporating a small organic molecule, bathophenanthroline (BPhen), into the CH3NH3PbBr3 emitter via a solvent engineering technique, the energy band levels of the perovskite can be tailored and the energy mismatch at the HTM/perovskite interface can be ameliorated through the formation of a graded emitter layer and accompanying morphological improvements. …”
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Non-fullerene acceptor-based solar cells : from structural design to interface charge separation and charge transport by Wang, Qungui, Li, Yuanzuo, Song, Peng, Su, Runzhou, Ma, Fengcai, Yang, Yanhui

“…The development of non-fullerene small molecule as electron acceptors is critical for overcoming the shortcomings of fullerene and its derivatives (such as limited absorption of light, poor morphological stability and high cost). …”
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Stapled peptides as a new technology to investigate protein–protein interactions in human platelets by Iegre, Jessica, Ahmed, Niaz S., Gaynord, Josephine S., Wu, Yuteng, Herlihy, Kara M., Tan, Yaw Sing, Lopes-Pires, Maria E., Jha, Rupam, Lau, Yu Heng, Sore, Hannah F., Verma, Chandra, O' Donovan, Daniel H., Pugh, Nicholas, Spring, David R.

“…New strategies for studying PPIs in human platelets are required to overcome limitations associated with conventional platelet research methods. For example, small molecule inhibitors can lack selectivity and are often difficult to design and synthesise. …”
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Numerical study of surfactants’ effect in surface agglomeration during 3D nano-inkjet printing by many-body dissipative particle dynamics by Aphinyan, Suphanat, Ang, Elisa Yun Mei, Geethalakshmi, K. R., Yeo, Jingjie, Lin, Rongming, Ng, Teng Yong

“…The surfactant is implemented in MDPD as a simple molecule composing of single hydrophilic bead and single hydrophobic bead. …”
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Effect of embedded nanoparticle surface chemistry on plasmonic organic photovoltaic devices by Wong, Terence Kin Shun

“…An alternative effective approach for both polymer and small molecule BHJ devices is core shell metal–silica NPs. …”
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Thermostable exoshells fold and stabilize recombinant proteins by Deshpande, Siddharth, Masurkar, Nihar D., Girish, Vallerinteavide Mavelli, Desai, Malan, Chakraborty, Goutam, Chan, Juliana M., Drum, Chester L.

“…Encapsulated enzymes retain the ability to metabolize small-molecule substrates, presumably via four 4.5-nm pores present in the tES shell. …”
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A pyrazolate-bridged cyclic tetranuclear copper(II) complex : synthesis, crystal structure and magnetic properties by Zhang, Hua, Fu, Degang, Ji, Feng, Wang, Guoxiong, Yu, Kaibe, Yao, Tianyang

“…In the crystal there is a hydrogen-bond network between water molecules and carboxylate groups which may control the packing. …”
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A rationally designed nitrogen-rich metal-organic framework and its exceptionally high CO2 and H2 uptake capability by Wang, Xiao-Jun, Li, Pei-Zhou, Chen, Yifei, Zhang, Quan, Zhang, Huacheng, Chan, Xiu Xiang, Ganguly, Rakesh, Li, Yongxin, Jiang, Jianwen, Zhao, Yanli

“…The MOF presents exceptionally high uptake capacity not only for CO2 but also for H2, which is attributed to favorable interactions between the gas molecules and the nitrogen-rich triazole units of the MOF proved by both experimental measurements and theoretical molecular simulations.…”
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Si nanowires organic semiconductor hybrid heterojunction solar cells toward 10% efficiency by He, Lining, Jiang, Changyun, Wang, Hao, Lai, Donny, Rusli

“…High-efficiency hybrid solar cells are fabricated using a simple approach of spin coating a transparent hole transporting organic small molecule, 2,2′,7,7′-Tetrakis-(N,N-di-4-methoxyphenylamino)-9,9′-spirobifluorene (Spiro-OMeTAD) on silicon nanowires (SiNWs) arrays prepared by electroless chemical etching. …”
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A naked-eye based strategy for semiquantitative immunochromatographic assay by Zhang, Daohong, Li, Peiwu, Zhang, Wen, Ding, Xiaoxia, Zhang, Qi, Li, Ran, Li, Chang Ming

“…Similar as the traditional strip assay for small molecule, the NSI-strip assay was also based on the competitive theory, difference was that the analyte competed three times with the capture reagent for the limited number of antibody binding sites. …”
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SELEKTIVITAS ETER MAHKOTA TERHADAP KATION LOGAM, PEMODELAN MOLEKUL BERDASARKAN METODE AB INITIO by , Yahmin, , Prof. Dr.rer.nat. Harno Dwi Pranowo, M.Si.

“…Microsolvation by addition of one water molecule increase the stability of [Mn+.12C4] and [Mn+.DBz12C4] complexes. …”