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6121
Manipulation of superparamagnetic bead through motion of domain wall
Published 2015“…This limitation was observed in drug discovery where effectiveness of chemotherapeutic drug is impeded by insufficient understanding of their means of action.2 Obtaining precise spatial manipulation over a large areas and control at single molecule level are also important for observing the dynamical interaction of single cells. …”
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Final Year Project (FYP) -
6122
Preliminary study on the preparation and characterization of novel organophilic membranes used for organic extraction
Published 2015“…When the feed wastewater was of pH higher than 8, it was suggested to adjust the pH of feed stream to below 5 to ensure the majority of phenol is present in the form of phenol molecule. Lastly, the test proved that increase in Re at two sides of the membrane indeed decreased liquid boundary layer resistance. …”
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Final Year Project (FYP) -
6123
Studies of interactions of STIM1 and GPCRs with their binding partners
Published 2015“…In this thesis, focus is on two transmembrane proteins: Adenosine A2A receptor (A2aR) as a model for G-protein coupled receptors (GPCRs) and stromal interacting molecule 1 (STIM1). GPCRs interact with extracellular compounds that activate cellular signalling pathways, leading to the generation of a large variety of cellular responses. …”
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Thesis -
6124
Photochrome aptamer switch assay
Published 2017“…The fluorescence decay of this aptasensor was also sensitive to ligand tetramethylrosamine (TMR) but presented no response to another non-binding triphenyl molecule rhodamine B (RhB), displaying good selectivity. …”
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Thesis -
6125
The cellular thermal shift assay : a novel strategy to study drug target engagement and resistance development in cancer therapy
Published 2018“…The drug binding to its target molecule determines the efficacy of therapeutics. Therefore, it is important to study drug target engagement in cells. …”
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Thesis -
6126
What are the intensities and line-shapes of the twenty four polarization terms in coherent anti-Stokes Raman spectroscopy?
Published 2015“…In theory, however, any third-order nonlinear spectroscopy with three different electric fields interacting with a molecule can be described by forty eight diagrams/terms. …”
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Journal Article -
6127
Single photon triggered dianion formation in TCNQ and F4TCNQ crystals
Published 2017“…Our measurements show the phenomenon that in this quinoid acceptor crystals in the absence of additional donor molecule, it is possible to resolve the two step formation of a doubly charged anion upon absorption of a single low energy photon (2.6 eV).…”
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Journal Article -
6128
Multi-photon absorption in metal-organic frameworks
Published 2018“…MOFs consisting of zirconium‐ and hafnium‐oxo‐clusters and featuring a chromophore linker based on the tetraphenylethene (TPE) molecule exhibit record high two‐photon absorption (2PA) cross‐section values, up to 3600 GM. …”
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Journal Article -
6129
Large-scale fabrication of nanostructure on bio-metallic substrate for surface enhanced raman and fluorescence scattering
Published 2019“…The crystal violet was selected as reporter molecule and both the intensity of Raman and fluorescence signals were enhanced because of the dual-mode SERS−SEF phenomena with enhancement factors (EFs) of 7.85 × 105 and 14.32, respectively. …”
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Journal Article -
6130
Revisiting metal electrodeposition in porous anodic alumina: toward tailored preparation of metal nanotube arrays
Published 2018“…The resultant metal nanotube arrays give rise to improved electro-catalytic activity to small molecule oxidation (such as ethanol and urea) due to the larger surface areas. …”
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Journal Article -
6131
Macrotheranostic Probe with Disease-activated Near-infrared Fluorescence, Photoacoustic and Photothermal Signals for Imaging-guided Therapy
Published 2018“…Supervisor to the small‐molecule counterpart probe, the macrotheranostic probe has an ideal biodistribution and renal clearance, permitting passive targeting of tumor, in‐situ enzymatic activation of multimodal signals, and effective photothermal therapy. …”
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Journal Article -
6132
First principle investigation of electronic transport properties of the edge shaped graphene-porphine molecular junction device
Published 2018“…Excellent coupling between the porphine molecule and graphene electrode is obtained by carbon-carbon covalent bonding and has been analyzed by the electron difference density. …”
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Journal Article -
6133
Effect of intermolecular dipole−dipole interactions on interfacial supramolecular structures of C3-symmetric hexa-peri-hexabenzocoronene derivatives
Published 2011“…This work provides an example of how intermolecular dipole−dipole interactions could enable fine control over the self-assembly of disklike π-conjugated molecules.…”
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Journal Article -
6134
Noncovalent functionalization of single-walled carbon nanotubes
Published 2011“…Cognizant of the structural properties of the functional molecules on the SWNTs, we present some of the recent work carried out by ourselves and others under the umbrella of the following three subtopics: (i) aromatic small-molecule-based noncovalent functionalization, (ii) biomacromolecule-based noncovalent functionalization, and (iii) polymer-based noncovalent functionalization. …”
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Journal Article -
6135
Artificial neural network-based drug design for diabetes mellitus using flavonoids
Published 2011“…Three computer experiments were conducted to study the influence of hydrogen (H), hydroxyl (OH), and methoxyl (CH3) functional groups on eight substitution sites of the lead flavone molecule and to predict potential ARIs. Of 6561 possible flavones and flavonols, in experiment 1, we predicted 69 potent ARIs, and in experiment 2, we predicted 346 compounds with strong RS activity. …”
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Journal Article -
6136
Mildly reduced graphene oxide-Ag nanoparticle hybrid films for surface-enhanced Raman scattering
Published 2013“…This will further enrich the application of surface-enhanced Raman scattering in molecule detection.…”
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Journal Article -
6137
The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)
Published 2012“…FK-506 binding protein 38 (FKBP38) has been reported to interact with Bcl-2, suggesting that FKBP38 could act as a docking molecule to localize Bcl-2 at the mitochondrial membrane [Shirane, M. and Nakayama, K.I. (2003) Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis. …”
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Journal Article -
6138
Phenomenological model of heat transfer in hard-disk air bearing based on nonlocal behavior in air molecular gas
Published 2013“…In this paper, a new phenomenological model of heat transfer in hard-disk air bearing based on nonlocal behavior in air molecule is developed. Analysis of the model shows that it is a more accurate to simulate the behavior of heat transfer due to heat conduction and the viscous dissipation for Couette flow case. …”
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Journal Article -
6139
RNA biology in a test tube-an overview of in vitro systems/assays
Published 2013“…Finally, new techniques, such as single-molecule studies, are continuously being established, providing new and important insights into the field. …”
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Journal Article -
6140
Layer-by-layer assembled solid polymer electrolyte for electrochromic devices
Published 2013“…Characterization of film structure and growth shows good incorporation of electrostatic and hydrogen bonding, because of the versatile control of the ionization of poly(acrylic acid) (PAA), which serves as a bridging molecule. Ionic conductivity values, as described by the Vogel−Fulcher−Tammann equation, are found to be above 10−5 S/cm for the dried electrolyte at room temperature and moderate humidity (52%RH). …”
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Journal Article