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6141
Molecular and Mesoscale Mechanisms of Osteogenesis Imperfecta Disease
Published 2011“…Collagen is a crucial structural protein material, formed through a hierarchical assembly of tropocollagen molecules, arranged in collagen fibrils that constitute the basis for larger-scale fibrils and fibers. …”
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6142
Quantum degenerate Bose-Fermi mixture of chemically different atomic species with widely tunable interactions
Published 2012“…Our work opens up the prospect to create chemically stable, fermionic ground-state molecules of [superscript 23]Na-[superscript 40]K, where strong, long-range dipolar interactions would set the dominant energy scale.…”
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6143
Generating spatially and temporally controllable long-range concentration gradients in a microfluidic device
Published 2012“…Here we have achieved rapid generation of spatially and temporally controllable concentration gradients of diffusible molecules (i.e. proteins or toxins) in a portable microfluidic device. …”
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6144
MicroRNAs can generate thresholds in target gene expression
Published 2012“…MicroRNAs (miRNAs) are short, highly conserved noncoding RNA molecules that repress gene expression in a sequence-dependent manner. …”
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6145
Investigation of the synthesis, activation, and isosteric heats of CO₂ adsorption of the isostructural series of metal-organic frameworks M₃(BTC)₂ (M = Cr, Fe, Ni, Cu, Mo, Ru)...
Published 2013“…These behaviors were attributed to the presence of residual guest molecules in the case of Ni₃(BTC)₂(Me₂NH)₂(H₂O) and the increased charge of the dimetal secondary building unit in [Ru₃(BTC)₂][BTC].…”
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6146
‘Gobbling drops’: the jetting–dripping transition in flows of polymer solutions
Published 2013“…This thinning process of the ligaments that are subjected to a constant axial force is driven by surface tension and resisted by the viscoelasticity of the dissolved polymeric molecules. Analysis of this transition provides a new experimental method to probe the rheological properties of solutions when minute concentrations of macromolecules have been added.…”
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6147
Cytochrome P450 Drives a HIF-Regulated Behavioral Response to Reoxygenation by C. elegans
Published 2014“…CYP-13A12 promotes oxidation of polyunsaturated fatty acids into eicosanoids, signaling molecules that can strongly affect inflammatory pain and ischemia-reperfusion injury responses in mammals. …”
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6148
Efficient Calculation of Molecular Configurational Entropies Using an Information Theoretic Approximation
Published 2014“…The theory is presented together with applications to the calculation of the entropies of a variety of small molecules and the binding entropy change for a series of HIV protease inhibitors. …”
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6149
Cation exchange at the secondary building units of metal–organic frameworks
Published 2014“…This technique has been used extensively to enhance the properties of nanocrystals and molecules, but the extent of its applications for MOFs is still expanding. …”
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6150
Modifications of Microvascular EC Surface Modulate Phototoxicity of a Porphycene anti-ICAM-1 Immunoconjugate; Therapeutic Implications
Published 2015“…Inflammation and shear stress can upregulate expression of cellular adhesion molecules in endothelial cells (EC). The modified EC surface becomes a mediating interface between the circulating blood elements and the endothelium, and grants opportunity for immunotherapy. …”
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6151
Dynamic Nuclear Polarization of [superscript 17] O: Direct Polarization
Published 2015“…The >10 000-fold savings in acquisition time enabled a series of biologically relevant small molecules to be studied with small sample sizes and the measurement of various quadrupolar parameters. …”
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6152
Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil
Published 2015“…The associated phase separation allows measuring the partitioning of small molecules between the aqueous phase and nanoparticles; data suggests that interactions are enhanced by decreasing the particle size. …”
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6153
Crystalline silicon core fibres from aluminium core preforms
Published 2015“…The aluminium atoms initially in the core reduce the silica, to produce silicon atoms and aluminium oxide molecules. The silicon atoms diffuse into the core, forming a large phase-separated molten silicon domain that is drawn into the crystalline silicon core fibre. …”
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6154
Facile synthesis of 3 D platinum dendrites with a clean surface as highly stable electrocatalysts
Published 2014“…Thanks to its unique 3 D morphology composed of interconnected 1 D Pt nanorods/wires, the unsupported 3 D Pt nanodendrites exhibit higher stability and activity than commercial carbon black supported Pt nanoparticles and Pt black electrocatalysts for the oxygen reduction reaction and oxidation of small fuel molecules.…”
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6155
Theranostic quantum dots for crossing blood–brain barrier in vitro and providing therapy of HIV-associated encephalopathy
Published 2014“…The blood–brain barrier (BBB) is a complex physiological checkpoint that restricts the free diffusion of circulating molecules from the blood into the central nervous system. …”
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6156
Designed di-heme binding helical transmembrane protein
Published 2014“…In this work, we report the design and characterization of a transmembrane protein, termed HETPRO (HEme-binding Transmembrane PROtein), that binds two molecules of heme in a membrane and catalyzes oxidation/reduction reactions. …”
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6157
Designing non-native iron-binding site on a protein cage for biological synthesis of nanoparticles
Published 2014“…Electrostatic interactions between anionic amino acids and cationic iron molecules drive the formation of iron oxide nanoparticles within the engineered E2 protein cages. …”
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6158
Construction of heterostructured Fe2O3-TiO2 microdumbbells for photoelectrochemical water oxidation
Published 2020“…With the assistance of preferentially adsorbed hexadecylamine molecules, amorphous TiO2 nanospheres with tunable size are grown at the two ends of Fe-based metal-organic compound microrods. …”
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6159
Improved adhesion and performance of vertically-aligned mesoporous silica-nanochannel film on reduced graphene oxide for direct electrochemical analysis of human serum
Published 2020“…Owing to the electroactive properties of rGO, VMSF/rGO/GCE is able to parallel or simultaneously detect small drugs or biomarkers with high sensitivity and distinct oxidation potential for different electroactive organic molecules. Combining the anti-fouling and anti-inference ability of VMSF, direct analysis of small drugs or biomarkers in complex biological (serum) sample is demonstrated.…”
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6160
Thanatin : An emerging host defense antimicrobial peptide with multiple modes of action
Published 2021“…This promising AMP requires further research for the development of novel molecules for the treatment of infections caused by drug resistant pathogens.…”
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