Supported iridium catalyst for the green synthesis of 3,3′-bis(indolyl)methanes using methanol as the bridging methylene source by Qiang, Wenwen, Liu, Xiang, Loh, Teck-Peng

“…The overall simplicity, chemoselectivity and sustainability of the catalytic system make this approach a valuable and step-economical tool to construct C-C bond directly from methanol in the synthesis of more complex molecules. x 2 x…”
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Zero-valent species of group 13–15 elements by Ota, Kei, Kinjo, Rei

“…Computational studies providing reinterpretation of bonding involved in well-known molecules, such as carbodiphosphorane, have opened up the area. …”
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Mechanosynthesis of higher-order cocrystals: tuning order, functionality and size in cocrystal design by Ng, Zi Xuan, Tan, Davin, Teo, Wei Liang, León, Felix, Shi, Xiaoyan, Sim, Ying, Li, Yongxin, Ganguly, Rakesh, Zhao, Yanli, Mohamed, Sharmarke, García, Felipe

“…To date, numerous examples of multicomponent crystals comprising organic molecules have been reported. However, the crystal engineering of cocrystals comprising both organic and inorganic chemical units is still poorly understood and mostly unexplored. …”
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Bio-inspired functional coacervates by Chen, Shujun, Guo, Qi, Yu, Jing

“…They also serve as good delivery platforms for different types of molecules. In this review, we briefly discuss some important extracellular coacervate systems, including mussel adhesives, sandcastle worm glue, squid beak, and tropoelastin. …”
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Mechanistic insights into the activities of major families of enzymes in bacterial peptidoglycan assembly and breakdown by Kwan, Jeric Mun Chung, Qiao, Yuan

“…In addition, soluble peptidoglycan fragments derived from bacteria are increasingly recognised as key signalling molecules in mediating diverse intra- and inter-species communication in nature, including in gut microbiota-host crosstalk. …”
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Synergistic copper-aminocatalysis for direct tertiary 𝜶-alkylation of ketones with electron-deficient alkanes by Shan, Qi-Chao, Wu, You-Wei, Chen, Mu-Xiang, Zhao, Xuefei, Loh, Teck-Peng, Hu, Xu-Hong

“…The findings contribute to the advancement of alkylation techniques, offering a practical and efficient route for the construction of C(sp3)─C(sp3) bonds, and paving the way for further developments in the synthesis of complex organic molecules.…”
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Synthesis of azahexabenzocoronenium salts through a formal [3 + 3] cycloaddition strategy by Zhang, Xinjiang, Li, Donglin, Tan, Cheryl Cai Hui, Hanindita, Fiona, Hamamoto, Yosuke, Foster, Adam S., Kawai, Shigeki, Ito, Shingo

“…Heteroatom-embedded hexa-peri-hexabenzocoronene (HBC) molecules exhibit interesting properties depending on the number and position of the introduced heteroatoms and are promising materials for applications in organic electronics and supramolecular chemistry. …”
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Sub-micrometer electrospray ionization emitter enables direct infusion native mass spectrometric analysis of proteins and protein-ligand complexes in NaCl, Tris-HCl buffer by Lim, Su Wei

“…To stabilize the native structures of proteins and protein-ligand complexes during analysis, salts and non-volatile molecules are a necessary addition in buffers. However, they tend to form adducts with analyte ions, increase background chemical noise and reduce signal-to-noise (S/N) ratios in mass spectral data. …”
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Tin-free radical mediated C-C bond formation via the Xanthate transfer by Goh, Kelvin Kau Kiat

“…The goal is to develop novel tin-free solutions in the C-C bond formation for the synthesis of highly functionalized molecules which had otherwise been plagued by acid-base problems in ionic chemistry. …”
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Lipodisks integrated with weak affinity chromatography enable fragment screening of integral membrane proteins by Duong-Thi, Minh-Dao, Bergström, Maria, Edwards, Katarina, Eriksson, Jonny, Ohlson, Sten, To Yiu Ying, Janet, Torres, Jaume, Agmo Hernández, Víctor

“…In this work we present a novel strategy for rapid identification of molecules capable of binding to a selected membrane protein. …”
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MicroRNAs and their potential therapeutic applications in neural tissue engineering by Nguyen, Lan Huong, Diao, Hua Jia, Chew, Sing Yian

“…After injuries, the local microenvironment often contains potent inhibitory molecules and glial scars, which do not actively support axonal regrowth. …”
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An organic dye with very large Stokes-shift and broad tunability of fluorescence: Potential two-photon probe for bioimaging and ultra-sensitive solid-state gas sensor by He, Tingchao, Wang, Yue, Tian, Xiaoqing, Gao, Yang, Zhao, Xin, Grimsdale, Andrew Clive, Lin, Xiaodong, Sun, Handong

“…Light-emitting nonlinear optical molecules, especially those with large Stokes shifts and broad tunability of their emission wavelength, have attracted considerable attention for various applications including biomedical imaging and fluorescent sensors. …”
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Roles of computational modelling in understanding p53 structure, biology, and its therapeutic targeting by Tan, Yaw Sing, Mhoumadi, Yasmina, Verma, Chandra Shekhar

“…This review describes how computational modelling has played key roles in understanding structural-dynamic aspects of p53, formulating hypotheses about domains that are beyond current experimental investigations, and the development of therapeutic molecules that target the p53 pathway.…”
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The gut microbiota influences blood-brain barrier permeability in mice by Braniste, Viorica, Al-Asmakh, Maha, Kowal, Czeslawa, Anuar, Farhana, Abbaspour, Afrouz, Tóth, Miklós, Korecka, Agata, Bakocevic, Nadja, Ng, Lai Guan, Kundu, Parag, Gulyás, Balázs, Halldin, Christer, Hultenby, Kjell, Nilsson, Harriet, Hebert, Hans, Volpe, Bruce T., Diamond, Betty, Pettersson, Sven

“…Pivotal to brain development and function is an intact blood-brain barrier (BBB), which acts as a gatekeeper to control the passage and exchange of molecules and nutrients between the circulatory system and the brain parenchyma. …”
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Nanoparticle Functionalization and Its Potentials for Molecular Imaging by Thiruppathi, Rukmani, Mishra, Sachin, Ganapathy, Mathangi, Padmanabhan, Parasuraman, Gulyás, Balázs

“…This also explains how nanoparticles interacting at molecular level, when functionalized with molecules can target the cells of interest or substances with high specificity, reducing background signal and allowing simultaneous therapies to be carried out while imaging. …”
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A new model for fluid velocity slip on a solid surface by Shu, Jian-Jun, Teo, Ji Bin Melvin, Chan, Weng Kong

“…A general adsorption model is developed to describe the interactions between near-wall fluid molecules and solid surfaces. This model serves as a framework for the theoretical modelling of boundary slip phenomena. …”
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Transcriptome alterations of vascular smooth muscle cells in aortic wall of myocardial infarction patients by Wongsurawat, Thidathip, Woo, Chin Cheng, Giannakakis, Antonis, Lin, Xiao Yun, Cheow, Esther Sok Hwee, Lee, Chuen Neng, Richards, Mark, Sze, Siu Kwan, Nookaew, Intawat, Sorokin, Vitaly, Kuznetsov, Vladimir Andreevich

“…The intersection of the top candidate molecules from the transcriptome and proteome highlighted overexpression.…”
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Water-promoted C-S bond formation reactions by Xie, Peizhong, Wang, Jinyu, Liu, Yanan, Fan, Jing, Wo, Xiangyang, Fu, Weishan, Sun, Zuolian, Loh, Teck-Peng

“…Allylic sulfones, owning to their widespread distributions in biologically active molecules, received increasing attention in the past few years. …”
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Dual functional dinuclear platinum complex with selective reactivity towards c-myc G-quadruplex by He, Lei, Meng, Zhenyu, Xu, Dechen, Shao, Fangwei

“…G-quadruplexes (GQ) folded by the oncogenic G-rich sequences are the promising targets for developing anticancer therapeutic molecules. However, the current drug development mainly focused on non-covalent dynamic binders to stabilize GQ structures, while the covalent targeting from inorganic complexes via chelating principles, as a potent therapeutic strategy was surprisingly lack of exploration. …”
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Quantum plasmonics of finite-size particles with coherent anti-Stokes Raman scattering by Kam, Chan Hin, Ooi, Raymond Chong Heng

“…The quantum particle is composed of molecules driven by three laser fields and produces a coherent anti-Stokes Raman scattering (CARS) signal which is enhanced by plasmonic resonance of the metallic particle. …”
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