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6261
Designing Novel DNA-Binding Proteins with Generative Deep Learning
Published 2023“…This thesis presents a novel framework for gen- erating protein backbones that exhibit affinity for DNA molecules. The proposed methodology leverages Graph Neural Networks (GNNs) for encoding protein struc- tures and diffusion models for conditional sampling. …”
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Thesis -
6262
Theoretical analysis and design of a double-clamped microchannel resonator
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Thesis -
6263
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6264
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6265
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6266
Study on the effect of perfusion pressure on decellularisation of porcine oesophagi
Published 2021“…A suitable scaffold for cell transplantation 3. Bio-reactive molecules to promote growth and cell regeneration This study focused on attaining the best possible ECM for tissue regeneration of the oesophagus. …”
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Final Year Project (FYP) -
6267
PAA-templated CuO nanoparticles : synthesis and self-assembly
Published 2009“…Molecular self-assembly is a strategy for nanofabrication that involves designing molecules and supramolecular entities so that shape-complementarity causes them to aggregate into desired structures. …”
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Final Year Project (FYP) -
6268
Development of polyimide membrane for gas permeation
Published 2009“…This was due to the thermal labile PVP acting as a pore-forming agent in the CMS membranes during pyrolysis which provided an enhanced diffusional pathway through the CMS membranes for the gas molecules. Furthermore, increasing the pyrolysis temperature from 400°C to 450°C yielded increases in permeation rates of CO2 and O2. …”
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Final Year Project (FYP) -
6269
Creep rupture of nanocomposites.
Published 2009“…The study of these cylindrical, carbon-based molecules has led to numerous findings of their multifunctional properties – high strength, high stiffness, high flexibility, low density, and good electrical and thermal conductivities. …”
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Final Year Project (FYP) -
6270
Adsorption of volatile organic compounds onto activated carbon
Published 2009“…The solid surface tends to satisfy these residual forces by attracting and retaining on its surface the molecules, atoms, or ions of the gas or liquid. There are two types of adsorption which are physisorption and chemisorption that involve different forces. …”
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Final Year Project (FYP) -
6271
Development, processing and characterization of advanced polymer thin and ultra thin film systems for semiconductor manufacturing and optoelectronic devices
Published 2009“…Thin films based on small organic molecules, polymers and organic-inorganic hybrids were prepared and studied. …”
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Research Report -
6272
Ceramics-based electrochemical uric acid biosensor
Published 2010“…The combination of carbon as the substrate, the overlying Fe3O4 layer and the conductive gold coating showed good adsorption properties for the uricase enzyme molecules and yielded good results. 5μl of 5 mg/ml uricase was immobilised onto the electrode surfaces by physical adsorption or physiosorption for a period of 24 hours at 4oC. …”
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Final Year Project (FYP) -
6273
Fouling of reverse osmosis and nanofiltration membranes by biological macromolecules - probing the foulant-membrane and foulant-foulant interactions
Published 2010“…The project investigated the dependence of limiting flux on intermolecular interaction between foulant molecules. It was observed that the limiting flux was directly proportional to the intermolecular electrostatic repulsive force and that conditions enhancing foulant‐deposited‐foulant repulsion resulted in greater limiting flux values. …”
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Research Report -
6274
Identification and characterization of angiopoietin-like 4 (ANGPTL4) interacting proteins in wound repair
Published 2010“…Cutaneous wound healing is a complex and highly coordinated process of proliferation and migration of keratinocytes at the wound edge through interactions of different signaling molecules. Growth factors, transmembrane protein integrins and extracellular matrix play an important role in epidermal wound healing process, although the interplay among these proteins is poorly understood. …”
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Thesis -
6275
Nanoelectronic biosensing of dynamic cellular activities
Published 2011“…The detection platform provide a novel tool to reveal the poorly understood signaling mechanisms of the molecules as well as their relevance in secretion related disease.…”
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Thesis -
6276
Synthesis of building blocks for two-dimensional supramolecular assembly by hydrogen bonding between melamine and imide functionalities
Published 2011“…Self-assembly by hydrogen bonding provides a mechanism for assembling large numbers of molecules into stable structures which lead to synergistic and emergent properties that are not intrinsic to the building blocks themselves. …”
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Final Year Project (FYP) -
6277
Frequency-domain fluorescence lifetime imaging (FD-FLIM).
Published 2011“…Lifetime of different fluorophores can become the important source of characteristic information especially on the properties of the fluorescent molecules themselves or the changes in their microenvironment. …”
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Final Year Project (FYP) -
6278
Profiling and authentication of Triticum aestivum (浮小麦).
Published 2011“…Currently, researches done are mainly focusing on small molecules that may have biological activities. In this study, we report the discovery of Cysteine-rich peptides (CRPs) in Triticum aestivum (浮小麦), which is the immature form of wheat used in TCM to treat night sweat. …”
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Final Year Project (FYP) -
6279
Shark egg-case cross-link chemistry : biomimetic model of densely cross-linked collagen
Published 2012“…The egg case is of interest because of its toughness, elasticity and its ability to simultaneously regulate the diffusional flow of small molecules and ions in and out of itself with ease. …”
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Final Year Project (FYP) -
6280
Transdermal drug delivery
Published 2013“…Nanospheres were used to simulate drug molecules and the penetration efficiency after application of ultrasound was found to increase significantly for particles of diameter 60nm and more than 5 times for particles of diameter 840nm. …”
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Final Year Project (FYP)