Solvent-induced electrochemistry at an electrically asymmetric carbon Janus particle by Liu, Albert Tianxiang, Kunai, Yuichiro, Cottrill, Anton L, Kaplan, Amir, Zhang, Ge, Kim, Hyunah, Mollah, Rafid S, Eatmon, Yannick L, Strano, Michael S

“…Doping also occurs when surface adsorbed molecules modify the Fermi level of low dimensional materials such as carbon nanotubes. …”
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A combined photoionization time-of-flight mass spectrometry and laser absorption spectrometry flash photolysis apparatus for simultaneous determination of reaction rates and produc... by Middaugh, Joshua E, Buras, Zachary J, Matrat, Mickael, Chu, Te-Chun, Kim, Young-Seok, Alecu, Ionut M, Vasiliou, AnGayle K, Goldsmith, C Franklin, Green, William H

“…The sensitivity of both the LAS and PI TOF-MS detection techniques is shown to be suitable for experiments with initial photolytically generated radical concentrations of ∼1 × 1012 molecules cm-3. As it is fast (μs time resolution) and non-intrusive, LAS is preferred for accurate kinetics (time-dependence) measurements. …”
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Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo by Fernandes, Ricardo A, Li, Chaoran, Wang, Gang, Yang, Xinbo, Savvides, Christina S, Glassman, Caleb R, Dong, Shen, Luxenberg, Eric, Sibener, Leah V, Birnbaum, Michael E, Benoist, Christophe, Mathis, Diane, Garcia, K Christopher

“…Their actions depend on TCR recognition of peptide-MHC molecules; yet the degree of peptide specificity of Treg-cell function, and whether Treg ligands can be used to manipulate Treg cell biology are unknown. …”
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Cell-free biosensors for rapid detection of water contaminants by Jung, Jaeyoung K, Alam, Khalid K, Verosloff, Matthew S, Capdevila, Daiana A, Desmau, Morgane, Clauer, Phillip R, Lee, Jeong Wook, Nguyen, Peter Q, Pastén, Pablo A, Matiasek, Sandrine J, Gaillard, Jean-François, Giedroc, David P, Collins, James J, Lucks, Julius B

“…We apply ROSALIND to detect a range of water contaminants, including antibiotics, small molecules and metals. We also show that adding RNA circuitry can invert responses, reduce crosstalk and improve sensitivity without protein engineering. …”
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Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras by Cohen, Malkiel A, Zhang, Shupei, Sengupta, Satyaki, Ma, Haiting, Bell, George W, Horton, Brendan, Sharma, Bandana, George, Rani E, Spranger, Stefani, Jaenisch, Rudolf

“…However, the tumors blunted the immune response by inducing infiltration of regulatory T cells and expression of immune-suppressive molecules similar to escape mechanisms seen in human cancer patients. …”
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Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras by Cohen, Malkiel A., Zhang, Shupei, Sengupta, Satyaki, Ma, Haiting, Bell, George W., Horton, Brendan, Sharma, Bandana, George, Rani E., Spranger, Stefani, Jaenisch, Rudolf

“…However, the tumors blunted the immune response by inducing infiltration of regulatory T cells and expression of immune-suppressive molecules similar to escape mechanisms seen in human cancer patients. …”
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Ionic liquid‐mediated transdermal delivery of thrombosis‐detecting nanosensors by Bekdemir, Ahmet, Tanner, Eden EL, Kirkpatrick, Jesse, Soleimany, Ava P, Mitragotri, Samir, Bhatia, Sangeeta N

“…Upon reaching the systemic circulation, the nanosensors released reporter molecules into the urine by responding to activation of the clotting cascade and retained a diagnostic power for 24 hours in an acute pulmonary embolism mouse model. …”
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Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2.

“…Effective presentation of antigens by human leukocyte antigen (HLA) class I molecules to CD8+ T cells is required for viral elimination and generation of long-term immunological memory. …”
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Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2. by Shalek, Alexander K

“…Effective presentation of antigens by human leukocyte antigen (HLA) class I molecules to CD8+ T cells is required for viral elimination and generation of long-term immunological memory. …”
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Morphological Transitions of a Photoswitchable Aramid Amphiphile Nanostructure by Kim, Dae-Yoon, Christoff-Tempesta, Ty, Lamour, Guillaume, Zuo, Xiaobing, Ryu, Ki-Hyun, Ortony, Julia H

“…Self-assembly of small amphiphilic molecules in water can lead to nanostructures of varying geometries with pristine internal molecular organization. …”
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SM-Omics is an automated platform for high-throughput spatial multi-omics by Vickovic, S, Lötstedt, B, Klughammer, J, Mages, S, Segerstolpe, Å, Rozenblatt-Rosen, O, Regev, A

“…<jats:title>Abstract</jats:title><jats:p>The spatial organization of cells and molecules plays a key role in tissue function in homeostasis and disease. …”
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Observing Nearby Nuclei on Paramagnetic Trityls and MOFs via DNP and Electron Decoupling by Tan, Kong Ooi, Yang, Luming, Mardini, Michael, Boon Cheong, Choon, Driesschaert, Benoit, Dincă, Mircea, Griffin, Robert G

“…Despite its success in elucidating important structural information on biological and inorganic materials, the detailed polarization-transfer pathway from the electrons to the nearby and then the bulk solvent nuclei, and finally to the molecules of interest-remains unclear. In particular, the nuclei in the paramagnetic polarizing agent play significant roles in relaying the enhanced NMR polarizations to more remote nuclei. …”
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7.345 Using Simple Organisms to Model Human Diseases, Spring 2013 by Harris, Katie

“…Simple organisms such as baker&rsquo;s yeast, nematodes, fruit flies, zebrafish, mice and rats have allowed biologists to investigate disease at multiple levels, from molecules to behavior. In this course students will learn strategies of disease modeling by critically reading and discussing primary research articles. …”
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Dysfunctional tRNA reprogramming and codon-biased translation in cancer by Dedon, Peter C, Begley, Thomas J

“…Furthermore, systems-level analyses of 34 tRNA writers and 493 tRNA genes highlight the theme of tRNA epitranscriptome dysregulation in many cancers and identify candidate tRNA writers, tRNA modifications, and tRNA molecules as drivers of pathological codon-biased translation.…”
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Similarity based functionalization for enumeration of synthetically plausible chemical libraries surrounding a target by Sankaranarayanan, Karthik, Jensen, Klavs F.

“…Functionalization of lead compounds to create analogs is a challenging step in discovering new molecules with desired properties and it is conducted throughout the chemical industry, including pharmaceuticals and agrochemicals. …”
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Formation of nanoparticles of blue haze enhanced by anthropogenic pollution by Zhang, Renyi, Wang, Lin, Khalizov, Alexei F., Zhao, Jun, Zheng, Jun, McGraw, Robert L., Molina, Luisa Tan

“…With one cis-pinonic acid and three to five sulfuric acid molecules in the critical nucleus, the hydrophobic organic acid part enhances the stability and growth on the hydrophilic sulfuric acid counterpart. …”
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Structure of duplex DNA containing the cisplatin 1,2-{Pt(NH3)2}[superscript 2]+-d(GpG) crosslink at 1.77 [Angstrom] resolution by Todd, Ryan C., Lippard, Stephen J.

“…Another new feature of this model is the location of four octahedral [Mg(H2O)6]2+ ions associated with bases in the DNA major groove and the identification of 124 ordered water molecules that participate in hydrogen-bonding interactions with either the nucleic acid or the diammineplatinum(II) moiety.…”
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Enhancement of in vitro Translation by Gold Nanoparticle – DNA Conjugates by Park, Sunho, Hamad-Schifferli, Kimberly

“…Enhancement occurs via a combination of nonspecific adsorption of translation-related molecules and the ribosome to the AuNP−DNA and specific binding to the mRNA of interest. …”
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Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival bearing tumors derived from Brca1-deficient ovarian cancer cells by Goldberg, Michael Solomon, Xing, Deyin, Ren, Yin, Orsulic, Sandra, Sharp, Phillip A., Bhatia, Sangeeta N

“…Inhibition of the DNA repair enzyme poly(ADP-ribose) polymerase 1 (PARP1) with small molecules has been shown to be an effective treatment for ovarian cancer with BRCA mutations. …”
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Dinosaur peptides suggest mechanisms of protein survival by San Antonio, James D., Schweitzer, Mary H., Jensen, Shane T., Kalluri, Raghu, Buckley, Michael, Orgel, Joseph P. R. O.

“…The dinosaur peptides localized to fibril regions protected by the close packing of collagen molecules, and contained few acidic amino acids. Four peptides mapped to collagen regions crucial for cell-collagen interactions and tissue development. …”
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