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8041
Cellular crosstalk mechanism of Toll-like receptors in gingival overgrowth (Review)
Published 2015“…These observations suggest that TLRs provide new insight into the connection among infection, inflammation, drugs and gingival fibrosis, and are therefore efficient therapeutic target molecules. We hypothesize that TLRs are critical for the development and progression of gingival overgrowth, and thus blocking TLR expression may serve as a novel target for antifibrotic therapy.…”
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Journal Article -
8042
Peptide-assembled graphene oxide as fluorescent turn-on sensor for ultrasensitive Lipopolysaccharide (Endotoxin) detection
Published 2015“…Specificity tests were conducted with various biological molecules to evaluate the sensing performance. Results & Discussion Specific binding of LPS with peptide release the peptides from GO, resulting in fluorescence recovery, allowing ultrasensitive detection of LPS with the limit of detection of 130 pM, the most sensitive synthetic LPS sensors to-date. …”
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Journal Article -
8043
Plasmonic colloidosomes: dynamic three-dimensional platform for biphasic, microfluidic and airborne surface-enhanced raman scattering applications
Published 2019“…Current commercial sensing methods such as fluorescence, UV-vis and chromatography do not provide sufficient molecular fingerprints of target analytes to prevent false positives from similar molecules. As a temporary solution, surface-enhanced Raman scattering (SERS) has enabled ultratrace detection with highly specific molecular information, yet suffers the need for stringent laser alignment while only capable of static measurements due to the use of rigid 2D substrates. …”
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Thesis-Doctor of Philosophy -
8044
Bio-laser emission imaging and analysis of optical resonators
Published 2020“…This is achieved by studying how the size and concentration of gain molecules within the nucleus affect output characteristic of laser emission which includes laser modes, intensity, spectrum, and threshold. …”
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Final Year Project (FYP) -
8045
Controlling supramolecular chiral nanostructures by self-assembly of a biomimetic β-sheet-rich amyloidogenic peptide
Published 2020“…The presence of His-rich and Ala-rich segments results in an amphiphilic behavior and drives its assembly into fibrillar supramolecular chiral aggregates with helical ribbon configuration in solution, with the His-rich region exposed to the solvent molecules. Upon increase in concentration, the fibrils undergo gel formation, while preserving the same mesoscopic features. …”
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Journal Article -
8046
Ultrathin silica mesh protected Pt nanoparticles for hydrogen evolution reaction (HER)
Published 2021“…The remarkable catalytic stability and activity can be attributed to porous network of the SiO2 layers, which not only prevented Pt from sintering during HER, but also allowed reactant molecules to be transported through its pores easily to reach the active catalytic sites on encapsulated Pt nanoparticles. …”
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Final Year Project (FYP) -
8047
Fabrication and characterization of biomimetic reverse osmosis membrane for brackish water desalination
Published 2021“…The pRPH nanochannels are believed to provide a preferred passage for water molecules to diffuse through the PA active layer quickly with lower hydraulic resistance as well as a shorter diffusion distance. …”
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Final Year Project (FYP) -
8048
Tailored indium sulfide-based materials for solar-energy conversion and utilization
Published 2021“…Meanwhile, pleasurable characters of In2S3 have been modulated via defective engineering, doping, and hybridization (with inorganic materials or bio-molecules). Gratifyingly, In2S3-based photocatalytic, photoelectrocatalytic and photovoltaic systems have made significant impact on the field of energy and environmental issues. …”
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Journal Article -
8049
Plasmon enhancement of organic photovoltaic efficiency in bulk-heterojunction cells of P3HT/PCBM
Published 2009“…Through the use of citrate molecules as surfactants, we developed a novel method of deposition by immersing plasma-cleaned ITO substrates into an Au colloid to adhere 9-48nm Au nanoparticles onto the ITO surface without the need for any binding agents. …”
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Final Year Project (FYP) -
8050
Modelling bacterial chemotaxis for indirectly binding attractants
Published 2021“…In bacterial chemotaxis, chemoattractant molecules may bind either directly or indirectly with receptors within the cell periplasmic space. …”
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Journal Article -
8051
MYC overexpression in cancer increases chromatin interactions at superenhancers and c-Myc binding sites
Published 2022“…Our results suggest that c-Myc molecules are recruited to and accumulates within zones of high transcription activity, binding first at stable promoter binding sites at low expression levels, then at superenhancer binding sites when overexpressed. …”
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Thesis-Doctor of Philosophy -
8052
High performance electrically pumped semiconductor lasers
Published 2022“…The long-wave infrared band contains many fingerprint absorption peaks of gas molecules and is located within a low-loss atmospheric window, so the development of high-power long-wave infrared quantum cascade laser research is of great importance in the fields of gas sensing, free-space communication and infrared countermeasures. …”
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Thesis-Master by Coursework -
8053
Gold nanorods surface modification and bioconjugation for label-free biosensor
Published 2009“…Following EDC/NHS activation, anti-rabbit IgG was bioconjugated onto the MPA molecules present on the PEG/MPA-GNRs. The rabbit IgG was detected by the shift in the longitudinal peak of the antibody conjugated GNRs, which was produced by the formation of its antibody-antigen complex with the anti-rabbit IgG on the PEG/MPA-GNRs. …”
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Final Year Project (FYP) -
8054
N-heterocyclic carbene-mediated carbon-sulfur bond-forming reactions
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Journal Article -
8055
Bisguanidinium-pyridoxal phosphate catalysed asymmetric reactions
Published 2024“…Cofactors are essential non-protein molecules or ions that play a crucial role in facilitating the optimal functioning of enzymes. …”
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Thesis-Doctor of Philosophy -
8056
Investigating the effects of cellulose nanocrystals and genipin on upcycled keratin films for packaging applications
Published 2024“…However, there was a slight increase in hydrophobicity observed with the addition of genipin which can be attributed to the presence of non-covalent molecular interactions between the genipin molecules and the keratin chains. Biodegradation tests in soil and seawater environments were used to confirm biodegradability of the fabricated film samples, which revealed that the rate of degradation can be controlled by varying the amounts of cellulose nanocrystals and genipin. …”
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Final Year Project (FYP) -
8057
Mechanisms of stress transfer at the collagen fibril and proteoglycan gel interface in extra-cellular matrices
Published 2010“…These are: (1) the long-range order of radial (i.e. side-to-side) packing of collagen molecules in fibrils, the mechanics of fibril-fibril sliding during the elastic loading stage, and (2) the underlying (van Der Waals forces of) interactions between the glycosaminoglycans (GAGs), associated with collagen-bound PGs,from adjacent fibrils. …”
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Research Report -
8058
Theoretical studies and model calculations of femtosecond stimulated Raman spectroscopy
Published 2012“…The theoretical descriptions of Femtosecond stimulated Raman spectroscopy (FSRS) and its features were studied using three- state model and displaced harmonic oscillator model. Two molecules were studied using displaced harmonic oscillator model: Rhodamine 6G (R6G) and crystal violet (CV) and compared to experiment. …”
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Thesis -
8059
Understanding structural-property relationships in keratin hydrogels
Published 2013“…Results have shown the promising effect of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDAC) to be used as a catalyst for successful attachment of cysteine molecules on the Poly(acrylic acid) of 450 kDa in molecular weight, PAA450, that the 200 mM EDAC used was able to increase the thiol group concentration to 45.38 μM as compared to 0.942 μM measured in control using a thiol group assay. …”
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Final Year Project (FYP) -
8060
Transition metal-catalyzed functionalization of alkynes and arenes
Published 2014“…Transition metal-catalyzed reactions are one of the most powerful and direct approaches for the synthesis of organic molecules. During the past several decades, new synthetic methodologies come out continuously. …”
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Thesis