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8161
Magnetoresistance and magneto-plasmonic sensors for the detection of cancer biomarkers : A bibliometric analysis and recent advances
Published 2023“…These sensor technologies offer numerous advantages over their counterparts, such as minimal background noise, immunity to environmental influences, compatibility with nanofabrication methods, ability to detect multiple substances simultaneously, straightforward integration, high specificity, distinctive identifying capabilities, real-time monitoring, stability, label-free detection, and remarkable sensitivity for detecting individual molecules. Nevertheless, since the use of these techniques for cancer biomarker detection is relatively new, it is essential to conduct a bibliometric analysis and review recent literature to offer guidance to both early-career and established researchers in this domain. …”
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8162
Synergistic effects of aloe vera and moringa oleifera in chitosan-based composites for preservation of banana fruit
Published 2024“…This research leveraged chitosan's biocompatibility by using sodium tripolyphosphate (NaTPP) as a crosslinker to strengthen chitosan (CH) molecules via ionic gelation, with Tween 80 as an emulsifier. …”
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8163
Layer-by-Layer Nanoparticles for Systemic Codelivery of an Anticancer Drug and siRNA for Potential Triple-Negative Breast Cancer Treatment
Published 2016“…Layer-by-layer films were formed on nanoparticles by alternately depositing siRNA and poly-l-arginine; a single bilayer on the nanoparticle surface could effectively load up to 3500 siRNA molecules, and the resulting LbL nanoparticles exhibit an extended serum half-life of 28 h. …”
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8164
Hematocrit and flow rate regulate the adhesion of platelets to von Willebrand factor
Published 2016“…The work we present here is an important step forward from our earlier work on single molecules and extends into the collective cellular behavior of whole blood. …”
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8165
Assessing high school chemistry students’ modeling sub-skills in a computerized molecular modeling learning environment
Published 2016“…The organic chemistry part of the unit was taught in a Computerized Molecular Modeling (CMM) learning environment, where students explored daily life organic molecules through assignments and two CMM software packages. …”
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8166
Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1
Published 2017“…Induction of this group of genes may indicate a metabolic shift toward glycolysis and fatty acid synthesis to generate and maintain pools of intermediate molecules required for tissue repair, cell growth and compensatory hepatic cell proliferation. …”
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8167
Framework water capacity and infiltration pressure of MFI zeolites
Published 2017“…Accordingly, an estimated decrease of up to 50% in the framework water capacity was observed for these zeolites when compared to the fully-crystallized larger zeolites, where 35 ± 2 water molecules were required to saturate a unit cell. On the other hand, the water infiltration pressure for all of the zeolites was ≈95–100 MPa despite the differences in the synthesis procedure, indicating uniformity in the crystallized pore structure and surface chemistry. …”
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8168
Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites
Published 2017“…A fluorescence-based assay confirms that T-bet dimers are able to bring two independent DNA molecules into close juxtaposition. Furthermore, chromosome conformation capture assays confirm that T-bet functions in the direct formation of chromatin loops in vitro and in vivo. …”
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8169
A Myosin Va Mutant Mouse with Disruptions in Glutamate Synaptic Development and Mature Plasticity in Visual Cortex
Published 2017“…Here, in studies using the dominantnegative MyoVa neurological mutant mouse Flailer, we find that MyoVa plays an essential role in activity-dependent delivery of PSD-95 and other critical PSD molecules to synapses and in endocytosis of AMPA-type glutamate receptors (AMPAR) in the dendrites of CNS neurons. …”
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8170
Molecular dynamics and charge transport in organic semiconductors: a classical approach to modeling electron transfer
Published 2018“…Here we present LMD simulations of charge transfer between a pair of fullerene molecules, which commonly serve as electron acceptors in OSCs. …”
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8171
Isolation of exosomes from whole blood by integrating acoustics and microfluidics
Published 2018“…Exosomes are nanoscale extracellular vesicles that play an important role in many biological processes, including intercellular communications, antigen presentation, and the transport of proteins, RNA, and other molecules. Recently there has been significant interest in exosome-related fundamental research, seeking new exosome-based biomarkers for health monitoring and disease diagnoses. …”
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8172
Transcriptional Reversion of Cardiac Myocyte Fate During Mammalian Cardiac Regeneration
Published 2018“…These downstream signaling molecules are also modulated in the regenerating mouse heart. …”
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8173
A Raf-competitive K-Ras binder can fail to functionally antagonize signaling
Published 2018“…To understand this lack of signaling inhibition, we quantified the number of molecules of R11.1.6 expressed by the inducible cell lines and developed a simple mathematical model describing the competitive binding of Ras by R11.1.6 and Raf. …”
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8174
Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier
Published 2018“…There are 27 different claudin molecules, each with unique properties that render the mucosa an intact barrier that is permselective in a way that is consistent with cell physiology. …”
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8175
Harnessing neuroplasticity for clinical applications
Published 2019“…Improved understanding of adaptive mechanisms at every level, from molecules to synapses, to networks, to behaviour, can be gained from iterative collaborations between basic and clinical researchers. …”
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8176
Antigen structure affects cellular routing through DC-SIGN
Published 2020“…Antigens directed to endosomal compartments are degraded, and the peptides are presented on major histocompatibility complex class II molecules, thereby promoting immunity. Alternatively, HIV-1 can avoid degradation, as virus engagement with C-type lectin receptors (CLRs), such as DC-SIGN (DC-specific ICAM-3–grabbing nonintegrin) results in trafficking to surface-accessible invaginated pockets. …”
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8177
The Order-Disorder Continuum: Linking Predictions of Protein Structure and Disorder through Molecular Simulation
Published 2020“…We find that structure predictor performance from neural networks can be leveraged for the identification of highly dynamic regions within molecules, linked to disorder. Low accuracy structure predictions suggest a lack of static structure for regions that disorder predictors fail to identify. …”
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8178
Mechanistic study of the formation of ring-retaining and ring-opening products from the oxidation of aromatic compounds under urban atmospheric conditions
Published 2020“…These compounds, previously identified as highly oxygenated molecules (HOMs), are produced by more than one pathway with differing numbers of reaction steps with OH, including both auto-oxidation and phenolic pathways. …”
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8179
Investigation of the conserved reentrant membrane helix in the monotopic phosphoglycosyl transferase superfamily supports key molecular interactions with polyprenol phosphate subst...
Published 2020“…These unique amphiphilic molecules are best known as substrates of polytopic membrane proteins, including polyprenol-phosphate phosphoglycosyl and glycosyl transferases, and as components of more complex substrates. …”
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8180
ABC triblock bottlebrush copolymer-based injectable hydrogels: design, synthesis, and application to expanding the therapeutic index of cancer immunochemotherapy
Published 2020“…Following the synthesis and characterization of these materials in vitro, TBC micelles loaded with various biologically active small molecules were investigated as injectable hydrogels for sustained drug release in vivo. …”
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