Targeting MTHFD2 in acute myeloid leukemia by Pikman, Yana, Alexe, Gabriela, Furman, Andrew, Chen, Liying M., Frumm, Stacey M., Ross, Linda, Fenouille, Nina, Bassil, Christopher F., Gould, Joshua, Stone, Richard M., DeAngelo, Daniel J., Galinsky, Ilene, Clish, Clary B., Kung, Andrew L., Banerji, Versha, Stegmaier, Kimberly, Puissant, Alexandre, Lewis, Caroline, Ramos, Azucena, Hemann, Michael, Vander Heiden, Matthew G.

“…We integrated gene expression signatures generated from the treatment of AML cells with multiple small molecules known to promote AML differentiation and death. …”
Get full text
Get full text
Get full text
Get full text

Targeting MTHFD2 in acute myeloid leukemia by Pikman, Yana, Puissant, Alexandre, Alexe, Gabriela, Furman, Andrew, Chen, Liying M., Frumm, Stacey M., Ross, Linda, Fenouille, Nina, Bassil, Christopher F., Lewis, Caroline, Ramos, Azucena, Gould, Joshua, Stone, Richard M., DeAngelo, Daniel J., Galinsky, Ilene, Clish, Clary B., Kung, Andrew L., Hemann, Michael, Vander Heiden, Matthew G., Banerji, Versha, Stegmaier, Kimberly

“…We integrated gene expression signatures generated from the treatment of AML cells with multiple small molecules known to promote AML differentiation and death. …”
Get full text
Get full text
Get full text
Get full text

Complementary use of computer simulations and molecular-thermodynamic theory to model surfactant and solubilizate self-assembly by Stephenson, Brian C. (Brian Curtis)

Get full text

Amphiphilic linear-dendritic block copolymers for drug delivery by Nguyen, Phuong, Ph. D. Massachusetts Institute of Technology

Get full text

Structural and functional consequences of platinum anticancer drug binding to free and nucleosomal DNA by Todd, Ryan Christopher, 1981-

Get full text

Control of size and charge selectivity in amphiphilic graft copolymer nanofiltration membranes by Lovell, Nathan Gary

Get full text

Prediction of concentrations of reactive nitrogen species in aqueous solutions and cells by Lim, ChangHoon, Ph. D. Massachusetts Institute of Technology

Get full text

Beechwood xylan-derived dietary fibers: the production, structural properties, and mechanisms to modulate human gut microbiota by Zhao, Sainan

“…Extracellular xylo-oligosaccharides (XOS) degradation was observed for molecules with a DP exceeding 5. BWXF treatments altered the microbial community structures, and substrate size-dependent effects on the microbial composition and metabolic outputs were observed. …”
Get full text

Covalent organic frameworks for membrane separations by Siow, Samuel Wei Jian

“…COF membranes have demonstrated the ability to effectively separate nano-sized molecules based on size-selective transport through their well-ordered nano-pore structures. …”
Get full text

Development of aquaporin based biomimetic membranes for desalination applications by Li, Xuesong

“…Attributed to its extremely high permeability for water molecules as well as high rejection to small solutes, in recent years there is a surge to mimic the natural cellular membranes by incorporating AQPs into various ultrathin films for water filtration applications. …”
Get full text

Synthesis and characterization of zinc-aluminium layered double hydroxide nanocomposite prepared via coprecipitation method by Ali Ahmed, Abdullah Ahmed

“…The dielectric respone of the LDH is believed to be caused by two charge carriers: the protons of the LDH water molecules and the NO3 interlayer anions which can be described by the anomolous low frequency dispersion with the second type of Universal Power Law. …”
Get full text

In vitro interactions of the small heat shock protein chaperone human [alpha]B-crystallin with its physiological substrates in the lens [gamma]-crystallins by Acosta-Sampson, Ligia I

Get full text

Design, fabrication, and investigation of 2 μm GaSb-based diode lasers by Li, Xiang

“…It can slow down some fast-moving objects such as molecules or electrons and therefore measure some ultrafast processes, e.g., the relaxation processes of carriers in semiconductors, chemical reaction dynamics, and electro-optical sampling of high-speed electronics. …”
Get full text
Get full text

Printing of functional materials in 2D and 3D structures by Halevi, Oded

“…These are molecular nets with metal ions as nodes and organic molecules as linkers. Despite their extensive investigations in the past twenty years, the utilization of MOFs for industrial and commercial applications is scarce, due to physical and chemical limitations. …”
Get full text

Flame synthesis of nanostructured TiO2 for energy and environmental applications by Wu, Shuyang

“…The in situ DRIFTS study on CO2 photoreduction reveals that the surface OVs facilitate the chemical activation of CO2 molecules through one-electron injection process. This results in the formation of the key intermediate CO2- species which facilitates the CO2 photoreduction. …”
Get full text

Analysis of g s-transferase, protien tyrosine phosphatase 1B, nuclear factor kappa-B1 and leptin receptor genetic polymorphisms as risk factors for Malaysian type 2 diabetes mellit... by Etemad, Ali

“…In the human genome, several genes were reported as functional candidate genes for T2DM and its associated disease such as CVD, which have intense effects on metabolism, oxidative stress, enzymatic activity and inflammatory expression; genetic variation within these molecules could determine the insulin resistance or leptin regulation and directly increased the risk of T2DM and its complications. …”
Get full text

Molecularly Imprinted Polymer Layer Using Navicula sp. Frustules As Core Material For Lysozyme Recognition by Lim, Guat Wei

“…Conventionally, MIP prepared via bulk imprinting method usually showed poor binding site accessibility for targeted protein molecules. To overcome this drawback, significant amount of research works have been carried out using nanoparticles as core material for protein imprinting. …”
Get full text

Synthesis and characterization of hafnium and molybdenum bifunctional initiators for the preparation of triblock copolymers by Gabert, Andrea Jennifer

Get full text

Preparation of low-dimensional materials for plasmonic bio-sensing by Das, Chandreyee Manas

“…Many such works promised functionalization-free sensing of bio-molecules. With such inspiration, with the help of commercial sensors we performed an initial assessment of multiple TMDC based arrangements to arrive at the best configuration that we used further for functionalization-free sensing of protein-protein interactions. …”
Get full text

STUDI PROSES MASTIKASI DAN PENGGILINGAN KARET ALAM : PENGARUHNYA TERHADAP KARAKTERISTIK VULKANISASI DAN SIFAT FISIK VULKANISAT by , IR. ABU HASAN M.SI., , Prof. Ir. Rochmadi, SU., Ph.D.

“…The smaller the particle size, the larger the surface area of the carbon black per unit of mass, so that the adsorption of rubber molecules on the surface of carbon black increases. …”