Plastic surgery beyond the human genome by Pleat, J, Dunkin, C, Zitzmann, N

“…Genes provide the instruction template for cellular structure and function. RNA molecules act as intermediaries. However, the true intracellular and extracellular workhorses are proteins.…”

Reversible pressure-induced amorphization of a zeolitic imidazolate framework (ZIF-4). by Bennett, T, Simoncic, P, Moggach, SA, Gozzo, F, Macchi, P, Keen, D, Tan, J, Cheetham, A

“…This occurs irrespective of pore occupancy and takes place via a novel high pressure phase (ZIF-4-I) when solvent molecules are present in the pores. A significant reduction in bulk modulus upon framework evacuation is also observed for both ZIF-4 and ZIF-4-I.…”

IMMOBILIZATION OF SMALL PROTEINS IN CARBON NANOTUBES - HIGH-RESOLUTION TRANSMISSION ELECTRON-MICROSCOPY STUDY AND CATALYTIC ACTIVITY by Tsang, S, Davis, J, Green, M, Allen, H, Hill, O, Leung, Y, Sadler, P

“…The morphologies of the small proteins Zn2Cd5- metallothionein, cytochrome c3 and β-lactamase I immobilized inside carbon nanotubes have been studied by high-resolution transmission electron microscopy (HRTEM); single protein molecules and their associated forms were clearly observed inside the central cavity and a significant amount remained catalytically active indicating that no drastic conformational change had taken place.…”

(5-n-Hexyl-2-hydroxymethyl-1,3-dioxan2-yl)methanol by Zhang, M., Yuan, Xian-You, Ng, S.W.

“…In the title compound, C12H24O4, the dioxane ring adopts a chair conformation; the n-hexyl chain, which occupies an equatorial position, has an extended zigzag conformation. In the crystal, molecules are connected by O-H center dot center dot center dot O hydrogen-bonds into a zigzag chain running along the b axis, giving rise to a herringbone pattern.…”

1-Isopropenyl-1H-1,3-benzimidazol-2(3H)-one by Saber, A., Zouihri, H., Essassi, E.M., Ng, S.W.

“…In the crystal, adjacent molecules are linked by pairs of N-H center dot center dot center dot O hydrogen bonds into inversion dimers.…”

2-Chloro-3-nitropyridine by Ng, S.W.

“…In the crystal, adjacent molecules are linked by non-classical C-H center dot center dot center dot N and C-H center dot center dot center dot O hydrogen bonds, forming a layer motif.…”

5-Methoxy-2- (2-morpholinoethyl)iminiomethyl phenolate by Lair, N.M., Ng, S.W., Ali, Hapipah Mohd

“…Each of the two independent molecules of the title comound, C(14)H(20)N(2)O(3), exists in the zwitterionic form as the imino N atoms are protonated. …”
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2'-(2-Methyl-1H-indol-3-ylmethylene)-benzenesulfonohydrazide by Ali, Hapipah Mohd, Yusnita, J., Basirun, Wan Jefrey, Ng, Seik Weng

“…The molecules of the title compound, C16H15N3O2S, are linked by an N-H(indolyl)O center dot center dot center dot(sulfonyl) hydrogen bond into a linear chain that runs along the a axis. …”

2 '-(5-bromo-2-hydroxybenzylidene)benzenesulfonohydrazide by Ali, Hapipah Mohd, Ng, S.W., Jefrey, B.W., Laila, M.

“…The two symmetry-independent molecules of the title compound, C13H11ClN2O3S, are linked by N-H center dot center dot center dot Os (s = sulfonyl) and N-H center dot center dot center dot O-h (h = hydroxy) hydrogen bonds to furnish a chain that propagates along the a axis of the monoclinic unit cell.…”

Oral Bioavailability Enhancement Of Poorly Soluble And Poorly Permeable Drugs Using Self-Microemulsifying Drug Delivery Systems And The Effect Of Piperine by Chitneni , Mallikarjun

“…There are approximately 40% of new drug molecules discovered and some drugmolecules that are available in the market, having poor bioavailability due to poorsolubility and/or poor permeability. …”
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Single-stage DNA splicing system via Yusof-Goode approach by Wen Li, Lim

“…The motivation behind using the Y-G approach is to simulate the actual recombinant behaviours of deoxyribonucleic acid (DNA) molecules. The current laboratory experimental approaches to obtain the product of the DNA splicing process involve time and cost with high probability of not getting the desired results. …”
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Antibiotic purification by using zeolites adsorbent by Nur Munirah, Abd Wahab

“…Application in separation and purification processes often used the ability of zeolites and other molecular sieves to exclude larger molecules to enter the pores and admit smaller ones. …”
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Enzymatic production of cassava flour using pectinase by Prakash, Nagasvara Ravo

“…The starch granules in cassava is hold up by pectin molecules, in which its cell wall can be broken by pectinase enzyme activity. …”
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You smell : the mysterious science of scent by Becker, Rachel A

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Polymeric Nanoparticles Active against Dual-Species Bacterial Biofilms by Makabenta, Jessa Marie V., Park, Jungmi, Li, Cheng-Hsuan, Chattopadhyay, Aritra Nath, Nabawy, Ahmed, Landis, Ryan F., Gupta, Akash, Schmidt-Malan, Suzannah, Patel, Robin, Rotello, Vincent M.

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Host-microbe interactions and the behavior of Caenorhabditis elegans by Kim, Dennis H, Flavell, Steven W

“…The sensory nervous system of C. elegans detects diverse microbial molecules, ranging from metabolites produced by broad classes of bacteria to molecules synthesized by specific strains of bacteria. …”
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Implementation of Synthetic Pathways to Foster Microbe-Based Production of Non-Naturally Occurring Carboxylic Acids and Derivatives by Vila-Santa, Ana, Mendes, Fernão C., Ferreira, Frederico C., Prather, Kristala L. J., Mira, Nuno P.

“…Synthetic biology has been reshaping the range of molecules that can be produced by microbial cells by setting new-to-nature pathways that leverage on enzyme arrangements not observed in vivo, often in association with the use of substrates that are not enzymes’ natural ones. …”
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Bayesian optimization with known experimental and design constraints for chemistry applications by Hase, Florian

“…In addition, we illustrate their practical utility in two simulated chemical research scenarios: the optimization of the synthesis of o-xylenyl Buckminsterfullerene adducts under constrained flow conditions, and the design of redox active molecules for flow batteries under synthetic accessibility constraints. …”
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Optical Property Prediction and Molecular Discovery through Multi-Fidelity Deep Learning and Computational Chemistry by Greenman, Kevin P.

“…Optical properties are crucial for the design of molecules for numerous applications, including for display technologies and biological imaging. …”
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Definitions and Measures of Performance for Standard Biological Parts by Conboy, Caitlin, Braff, Jen, Endy, Drew

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