Stage B Heart Failure Is Ubiquitous in Emergency Patients with Asymptomatic Hypertension by Kimberly Souffront, Bret P. Nelson, Megan Lukas, Hans Reyes Garay, Lauren Gordon, Thalia Matos, Isabella Hanesworth, Rebecca Mantel, Claire Shubeck, Cassidy Bernstein, George T. Loo, Lynne D. Richardson

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Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation by Ander Puyalto, María Rodríguez-Remírez, Inés López, Irati Macaya, Elizabeth Guruceaga, María Olmedo, Anna Vilalta-Lacarra, Connor Welch, Sergio Sandiego, Silvestre Vicent, Karmele Valencia, Alfonso Calvo, Ruben Pio, Luis E. Raez, Christian Rolfo, Daniel Ajona, Ignacio Gil-Bazo

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Mortality in Patients Hospitalized With Acute Myocardial Infarction Without Standard Modifiable Risk Factors: The ARIC Study Community Surveillance by Zainali S. Chunawala, Melissa C. Caughey, Deepak L. Bhatt, Michael Hendrickson, Sameer Arora, Sripal Bangalore, John P. Erwin, Justin P. Levisay, Jonathan R. Rosenberg, Mark J. Ricciardi, Ron Blankstein, Kunihiro Matsushita, Sidney Smith, Arman Qamar

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Association of True Positivity with Serum Prostate-Specific Antigen Levels and Other Clinical Factors in Indeterminate PSMA-RADS-3A Lesions Identified on ¹⁸F-DCFPyL PET/... by Tushar Garg, Rudolf A. Werner, Hyun Woo Chung, Wajahat Khatri, Kenneth J. Pienta, Martin G. Pomper, Michael A. Gorin, Elie Saad, Steven P. Rowe

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Role of Cardiovascular Imaging in Risk Assessment: Recent Advances, Gaps in Evidence, and Future Directions by Francesco Perone, Marco Bernardi, Alban Redheuil, Dario Mafrica, Edoardo Conte, Luigi Spadafora, Fiona Ecarnot, Lale Tokgozoglu, Carlos G. Santos-Gallego, Sergio Emanuel Kaiser, Federica Fogacci, Annabelle Sabouret, Deepak L. Bhatt, Francesco Paneni, Maciej Banach, Raul Santos, Giuseppe Biondi Zoccai, Kausik K. Ray, Pierre Sabouret

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4468 Evaluating the Emerging Investigators Website as an Educational Resource for Early Career Researchers by Layla Fattah, Inga Peter, Jenny Lin, Janice Lynn Gabrilove

“…The Emerging Investigators website is designed to bring together resources, provide educational support and foster a community of early career researchers throughout the Mount Sinai Health System (MSHS). Locally designed and built, this web-based platform is developed using the principles of Community of Inquiry (COI), which considers how the design of online learning environments might best create and sustain a sense of community among learners. …”
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Impact of Tyrosine Kinase Inhibitors on the Immune Response to SARS-CoV-2 Vaccination in Patients with Non-Small Cell Lung Cancer by Norma Hernández-Pedro, Marisol Arroyo-Hernández, Pedro Barrios-Bernal, Eunice Romero-Nuñez, Victor A. Sosa-Hernandez, Santiago Ávila-Ríos, José Luis Maravillas-Montero, Rogelio Pérez-Padilla, Diego de Miguel-Perez, Christian Rolfo, Oscar Arrieta

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Cancer patient and provider responses to companion scales assessing experiences with LGBTQI-affirming healthcare by Mandi L. Pratt-Chapman, Mandi L. Pratt-Chapman, Mandi L. Pratt-Chapman, Yan Wang, Yan Wang, Gwendolyn P. Quinn, Sylvia Shirima, Sarah Adler, Ruta Brazinskaite, Charles Kamen, Asa Radix, Barbara Warren, Kristen Eckstrand, Ana Maria Lopez

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Best Case/Worst Case: protocol for a multisite randomised clinical trial of a scenario planning intervention for patients with kidney failure by Anne Buffington, Daniel Lam, Amar D Bansal, Karlie Haug, Amy Zelenski, Bret M Hanlon, Lily Stalter, Kristine L Kwekkeboom, Paul Rathouz, Katharine Cheung, Deidra Crews, Rebecca Frazier, Holly Koncicki, Alvin Moss, Maya Rao, Dawn F Wolfgram, Jeniann Yi, Carrie Brill, Rachael Kendrick, Toby C Campbell, Roy Jhagroo, Margaret Schwarze

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Cost‐Effectiveness of Icosapent Ethyl in REDUCE‐IT USA: Results From Patients Randomized in the United States by William S. Weintraub, Deepak L. Bhatt, Zugui Zhang, Sarahfaye Dolman, William E. Boden, Adam P. Bress, Brandon K. Bellows, Catherine G. Derington, Sephy Philip, Gabriel Steg, Michael Miller, Eliot A. Brinton, Terry A. Jacobson, Jean‐Claude Tardif, Christie M. Ballantyne, Paul Kolm

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Does Surgical Margin Width Remain a Challenge for Triple-Negative Breast Cancer? A Retrospective Analysis by Eduard-Alexandru Bonci, Ștefan Țîțu, Alexandru Marius Petrușan, Claudiu Hossu, Vlad Alexandru Gâta, Morvarid Talaeian Ghomi, Paul Milan Kubelac, Teodora Irina Bonci, Andra Piciu, Maria Cosnarovici, Liviu Hîțu, Alexandra Timea Kirsch-Mangu, Diana Cristina Pop, Ioan Cosmin Lisencu, Patriciu Achimaș-Cadariu, Doina Piciu, Hank Schmidt, Bogdan Fetica

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Predicting survival and neurological outcome in out-of-hospital cardiac arrest using machine learning: the SCARS modelResearch in context by Fredrik Hessulf, Deepak L. Bhatt, Johan Engdahl, Peter Lundgren, Elmir Omerovic, Aidin Rawshani, Edvin Helleryd, Christian Dworeck, Hans Friberg, Björn Redfors, Niklas Nielsen, Anna Myredal, Attila Frigyesi, Johan Herlitz, Araz Rawshani

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Quantitative chest computed tomography combined with plasma cytokines predict outcomes in COVID-19 patients by Guillermo Carbonell, Diane Marie Del Valle, Edgar Gonzalez-Kozlova, Brett Marinelli, Emma Klein, Maria El Homsi, Daniel Stocker, Michael Chung, Adam Bernheim, Nicole W. Simons, Jiani Xiang, Sharon Nirenberg, Patricia Kovatch, Sara Lewis, Miriam Merad, Sacha Gnjatic, Bachir Taouli

“…Patients (n = 152) from the Mount Sinai Health System in New York with plasma cytokine assessment and a chest CT within five days from admission were included. …”
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Importance of First Pass Reperfusion in Endovascular Stroke Care ‐ Insights From Thrombectomy and Aneurysm Registry (STAR) by Ilko L. Maier, Eyad Almallouhi, Marios‐Nikos Psychogios, Jan Liman, Sami Al Kasab, Ali Alawieh, Reda Chalhoub, Stacey Wolfe, Adam Arthur, Amir Shaban, Travis Dumont, Peter Kan, Joon‐Tae Kim, Reade De Leacy, Joshua Osbun, Ansaar Rai, Pascal Jabbour, Brian M. Howard, Min Park, Robert M. Starke, Roberto Crosa, Justin Mascitelli, Michael R. Levitt, Adam Polifka, Walter Casagrande, Shinichi Yoshimura, Charles Matouk, Richard W. Williamson, Benjamin Gory, Maxim Mokin, Isabel Fragata, Daniele G. Romano, Shakeel Chowdry, Mark Moss, Alejandro M. Spiotta, Daniel Behme

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Thrombectomy in Stroke Patients With Low Alberta Stroke Program Early Computed Tomography Score: Is Modified Thrombolysis in Cerebral Infarction (mTICI) 2c/3 Superior to mTICI 2b? by Sameh Samir Elawady, Brian Fabian Saway, Hidetoshi Matsukawa, Kazutaka Uchida, Steven Lin, Ilko Maier, Pascal Jabbour, Joon-Tae Kim, Stacey Quintero Wolfe, Ansaar Rai, Robert M. Starke, Marios-Nikos Psychogios, Edgar A Samaniego, Adam Arthur, Shinichi Yoshimura, Hugo Cuellar, Jonathan A. Grossberg, Ali Alawieh, Daniele G. Romano, Omar Tanweer, Justin Mascitelli, Isabel Fragata, Adam Polifka, Joshua Osbun, Roberto Crosa, Charles Matouk, Min S. Park, Michael R. Levitt, Waleed Brinjikji, Mark Moss, Travis Dumont, Richard Williamson, Pedro Navia, Peter Kan, Reade De Leacy, Shakeel Chowdhry, Mohamad Ezzeldin, Alejandro M. Spiotta, Sami Al Kasab

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Impact of Successful Recanalization and Clinical Outcomes of Patients With Acute Ischemic Stroke with 5 or More Thrombectomy Passes by Kazutaka Uchida, Mohammad‐Mahdi Sowlat, Hidetoshi Matsukawa, Sameh Samir Elawady, Ali Alawieh, Conor Cunningham, Sami Al Kasab, Ilko Maier, Pascal Jabbour, Joon‐Tae Kim, Stacey Quintero Wolfe, Ansaar Rai, Robert M Starke, Marios‐Nikos Psychogios, Amir Shaban, Adam Arthur, Hugo Cuellar, Jonathan A. Grossberg, Daniele G. Romano, Omar Tanweer, Justin Mascitelli, Isabel Fragata, Adam Polifka, Joshua Osbun, Roberto Crosa, Charles Matouk, Min S. Park, Michael R. Levitt, Waleed Brinjikji, Mark Moss, Richard Williamson, Pedro Navia, Peter Kan, Reade De Leacy, Shakeel Chowdhry, Mohamad Ezzeldin, Shinichi Yoshimura, Alejandro M. Spiotta

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The American Society of Pain and Neuroscience (ASPN) Evidence-Based Clinical Guideline of Interventional Treatments for Low Back Pain by Sayed D, Grider J, Strand N, Hagedorn JM, Falowski S, Lam CM, Tieppo Francio V, Beall DP, Tomycz ND, Davanzo JR, Aiyer R, Lee DW, Kalia H, Sheen S, Malinowski MN, Verdolin M, Vodapally S, Carayannopoulos A, Jain S, Azeem N, Tolba R, Chang Chien GC, Ghosh P, Mazzola AJ, Amirdelfan K, Chakravarthy K, Petersen E, Schatman ME, Deer T

“…Dawood Sayed,1 Jay Grider,2 Natalie Strand,3 Jonathan M Hagedorn,4 Steven Falowski,5 Christopher M Lam,1 Vinicius Tieppo Francio,6 Douglas P Beall,7 Nestor D Tomycz,8 Justin R Davanzo,9 Rohit Aiyer,10 David W Lee,11 Hemant Kalia,12,13 Soun Sheen,13 Mark N Malinowski,14,15 Michael Verdolin,16 Shashank Vodapally,17 Alexios Carayannopoulos,18– 20 Sameer Jain,21 Nomen Azeem,22,23 Reda Tolba,24,25 George C Chang Chien,26,27 Priyanka Ghosh,28 Anthony J Mazzola,29 Kasra Amirdelfan,30 Krishnan Chakravarthy,31,32 Erika Petersen,33 Michael E Schatman,34,35 Timothy Deer36 1Department of Anesthesiology and Pain Medicine, The University of Kansas Medical Center, Kansas City, KS, USA; 2University of Kentucky, Lexington, KY, USA; 3Interventional Pain Management, Mayo Clinic, Scottsdale, AZ, USA; 4iSpine Pain Physicians, Maple Grove, MN, USA; 5Functional Neurosurgery, Neurosurgical Associates of Lancaster, Lancaster, PA, USA; 6Department of Rehabilitation Medicine, University of Kansas Medical Center, Kansas City, KS, USA; 7Comprehensive Specialty Care, Edmond, OK, USA; 8AHN Neurosurgery, Allegheny General Hospital, Pittsburgh, PA, USA; 9AHN Neurosurgery, Forbes Hospital, Monroeville, PA, USA; 10Interventional Pain Management and Pain Psychiatry, Henry Ford Health System, Detroit, MI, USA; 11Physical Medicine & Rehabilitation and Pain Medicine, Fullerton Orthopedic Surgery Medical Group, Fullerton, CA, USA; 12Rochester Regional Health System, Rochester, NY, USA; 13Department of Physical Medicine & Rehabilitation, University of Rochester, Rochester, NY, USA; 14Adena Spine Center, Adena Health System, Chillicothe, OH, USA; 15Ohio University Heritage College of Osteopathic Medicine, Athens, OH, USA; 16Anesthesiology and Pain Medicine, Pain Consultants of San Diego, San Diego, CA, USA; 17Physical Medicine and Rehabilitation, Michigan State University, East Lansing, MI, USA; 18Department of Physical Medicine and Rehabilitation, Rhode Island Hospital, Newport Hospital, Lifespan Physician Group, Providence, RI, USA; 19Comprehensive Spine Center at Rhode Island Hospital, Newport Hospital, Providence, RI, USA; 20Neurosurgery, Brown University, Providence, RI, USA; 21Interventional Pain Management, Pain Treatment Centers of America, Little Rock, AR, USA; 22Department of Neurology, University of South Florida, Tampa, FL, USA; 23Florida Spine & Pain Specialists, Riverview, FL, USA; 24Pain Management, Cleveland Clinic, Abu Dhabi, United Arab Emirates; 25Anesthesiology, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA; 26Pain Management, Ventura County Medical Center, Ventura, CA, USA; 27Center for Regenerative Medicine, University Southern California, Los Angeles, CA, USA; 28Remedy Medical Group, San Francisco, CA, USA; 29Mount Sinai Health System, New York City, NY, USA; 30IPM Medical Group, Inc., Walnut Creek, CA, USA; 31Division of Pain Medicine, Department of Anesthesiology, University of California San Diego, San Diego, CA, USA; 32Va San Diego Healthcare, San Diego, CA, USA; 33Department of Neurosurgery, University of Arkansas for Medical Science, Little Rock, AR, USA; 34Department of Anesthesiology, Perioperative Care, and Pain Medicine, NYU Grossman School of Medicine, New York, New York, USA; 35Department of Population Health - Division of Medical Ethics, NYU Grossman School of Medicine, New York, New York, USA; 36The Spine and Nerve Center of the Virginias, Charleston, WV, USACorrespondence: Dawood Sayed, The University of Kansas Health System, 3901 Rainbow Blvd, Kansas City, KS, 66160, USA, Tel +1 913-588-5521, Email dsayed@kumc.eduIntroduction: Painful lumbar spinal disorders represent a leading cause of disability in the US and worldwide. …”
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Implementation of a Virtual Interprofessional ICU Learning Collaborative: Successes, Challenges, and Initial Reactions From the Structured Team-Based Optimal Patient-Centered Care... by Simon Zec, MD, Nika Zorko Garbajs, MD, Yue Dong, MD, Ognjen Gajic, MD, Christina Kordik, MA, Lori Harmon, RRT, MBA, CPHQ, Marija Bogojevic, MD, Romil Singh, MD, Yuqiang Sun, MD, Vikas Bansal, MD, Linh Vu, MD, Kelly Cawcutt, MD, John M. Litell, DO, Sarah Redmond, PhD, Eleanor Fitzpatrick, RN, Kirstin J. Kooda, PharmD, Michelle Biehl, MD, Neha S. Dangayach, MD, Viren Kaul, MD, June M. Chae, MD, Aaron Leppin, MD, Mathew Siuba, MD, Rahul Kashyap, MBBS, Allan J. Walkey, MD, Alexander S. Niven, MD, on behalf of the Structured Team-based Optimal Patient-Centered Care for Virus COVID-19 (STOP-VIRUS) Collaborative, Anthony Martinez, MD, Dean Meadows, MD, Helen Stinnett, BA, RRT, Michael Allison, MD, Olubukola Adeyemi, PharmD, Terry Herbert, BSN, RN, Gerald L. Weinhouse, MD, Namrata Patil, MD, MPH, Gaspar Hacobian, PharmD, BCPS, Kamen Rangelov, MD, Jillian Parker, RRT, Michael P. Smith, PharmD, BCCCP, Rachel Smith, RN, MSN, MBA, CCRN, Eliza Deery, MD, Andrea Harper, MS, Emily Davis, RN, CCRN, Grace M. Arteaga, MD, FAAP, FCCM, Jennifer L. Fleegel, RN, CCRN, Julie M. Duncan, RN, Kevin K. Graner, RPh, Tammy J. Schultz, RRT, LRT, Abhishek Giri, MBBS, Ashley Gill, RRT, Catherine L. Mielke, MS, APRN, CNS, Devang Sanghavi, MD, MHA, Jonathan K. Clark, RRT, Julie Shimp, RN, Lisa Marshall, MSN, RN, Michael Spiros, MSN, RN, Nirmaljot Kaur, MD, Sean P. Kiley, MD, Siva Naga Yarrarapu, MBBS, Teresa Keister, RN, Gage Stroope, LRT, CRT, Jackie Stark, PharmD, BCPS, Jessica Poehler, RN, Juan Pablo, Domecq Garces, MD, Nitesh Kumar Jain, MD, MBBS, Syed Anjum Khan, MD, Thoyaja Koritala, MD, Abigail La Nou, MD, FACEP, Christina Hall, MS, RN, Cindy Christensen, MSN, RN, FNP-BC, Kirsten Holbrook, RRT, Sara Toufar, PharmD, RPh, Sarah Normand, PharmD, RPh, Amy Spitzner, RN, CCRN, Carissa Quinn, APRN, CNS, DNP, Christina Xia, PharmD, BCCCP, Holly D. Behrns, LRT, RRT, Erin Barreto, PharmD, RPh, Jennifer Elmer, APRN, CNS, DNP, Sarah Chalmers, MD, PCCM, Macy Cooper, RN, Aaron Harthan, PharmD, BCPPS, Edmundo A. Martinez, MD, Jennifer A. Bandy, RN, BSN, John Sanford, RRT-ACCS, RRT-NPS, Jackie A. Guiliani, BSRT, RRT-NPS, Megan Kupferschmid, MSN, RN, P-CCRN, Anand Pariyadath, MD, Brandy Vitielliss, BSN, RN, Daniel Temas, MD, Smith F. Heavner, MS, RN, PCCN, Amanda Frary, MSN, RN, Murtaza Akhter, MD, Rania Rahman, MD, Mary Mulrow, RN, MN, CCRP, Tracy Cooper, RN, John M. Litell, DO, FACEP, June Mee Chae, MD, Kelly Cawcutt, MD, MS, FACP, FIDSA, Kirstin J. Kooda, PharmD, RPh, Michelle Biehl, MD, Neha S. Dangayach, MD, MSCR, Sarah Redmond, PhD, Viren Kaul, MD, Matthew Siuba, DO, Aaron B. Holley, MD, Alexander A. Kon, MD, MS, Amita Avadhani, PhD, DNP, CNE, DCC, ACNP-BC, NP-C, CCRN, FAANP, FCCM, Amy L. Dzierba, PharmD, FCCP, BCCCP, FCCM, Andre C. Kalil, MD, MPH, FACP, Kelly Cawcutt, MD, MS, FACP, FIDSA, Ashley D. DePriest, MS, RDN, CNSC, Bradley Peters, PharmD, RPh, BCSP, BCCCP, Brenda T. Pun, DNP, RN, FCCM, Courtney E. Bennett, DO, Eric Kriner, BS, RRT, Erin S. DeMartino, MD, Erin Strong, BSN, RN, CCRN, Giora Netzer, MD, Greg S. Martin, MD, MSc, FCCM, Jerry J. Zimmerman, MD, PhD, FCCM, Julia Taylor, MD, MA, HEC-C, Karen A. Korzick, MD, MA, FCCP, FACP, FCCM, Katherine Fischkoff, MD, MPA, FACS, Lewis J. Kaplan, MD, FACS, FCCM, Marlies Ostermann, MD, PhD, Mary Susan Gaeta, MD, FACP, Mary Faith Marshall, HEC-C, PhD, Nahreen Ahmed, MD, MPH, Paul Alan Nyquist, MD, MPH, Pooja A. Nawathe, MD, FAAP, CHSE-A, CHSOS, FCCM, Preeti R. John, MD, MPH, FACS, CPE, HEC-C, Uzma Syed, DO, FIDSA

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Editorial: Optimization of spine surgery outcomes in the pre-, peri-, and postoperative settings by Jonathan J. Rasouli, Jeremy Steinberger, Jeremy Steinberger

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Survey of pediatric dermatologist views on treatment for alopecia areata by David Bitterman, BA, Dov Bitterman, MD, Jacquelyn Sink, MD, Katya Harfmann, MD, Marcia Hogeling, MD, Christine T. Lauren, MD, MHA, Kimberly D. Morel, MD, Leslie Castelo-Soccio, MD, PhD, Nanette B. Silverberg, MD

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