Characterization of Anticancer Effects of the Analogs of DJ4, a Novel Selective Inhibitor of ROCK and MRCK Kinases by Vijay Pralhad Kale, Jeremy A. Hengst, Arati K. Sharma, Upendarrao Golla, Sinisa Dovat, Shantu G. Amin, Jong K. Yun, Dhimant H. Desai

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Preclinical efficacy for a novel tyrosine kinase inhibitor, ArQule 531 against acute myeloid leukemia by Ola A. Elgamal, Abeera Mehmood, Jae Yoon Jeon, Bridget Carmichael, Amy Lehman, Shelley J. Orwick, Jean Truxall, Virginia M. Goettl, Ronni Wasmuth, Minh Tran, Shaneice Mitchell, Rosa Lapalombella, Sudharshan Eathiraj, Brian Schwartz, Kimberly Stegmaier, Sharyn D. Baker, Erin Hertlein, John C. Byrd

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Colloidal Assemblies Composed of Polymeric Micellar/Emulsified Systems Integrate Cancer Therapy Combining a Tumor-Associated Antigen Vaccine and Chemotherapeutic Regimens by Chiung-Yi Huang, Shu-Yu Lin, Tsu-An Hsu, Hsing-Pang Hsieh, Ming-Hsi Huang

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Discovery of a Novel Template, 7-Substituted 7-Deaza-4′-Thioadenosine Derivatives as Multi-Kinase Inhibitors by Karishma K. Mashelkar, Woong Sub Byun, Hyejin Ko, Kisu Sung, Sushil K. Tripathi, Seungchan An, Yun A Yum, Jee Youn Kwon, Minjae Kim, Gibae Kim, Eun-Ji Kwon, Hyuk Woo Lee, Minsoo Noh, Sang Kook Lee, Lak Shin Jeong

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Translational research on drug development and biomarker discovery for hepatocellular carcinoma by Valerie Chew, Chien-Huai Chuang, Chiun Hsu

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Sorafenib after combination therapy with gemcitabine plus doxorubicine in patients with sarcomatoid renal cell Carcinoma: a prospective evaluation by Staehler M, Haseke N, Roosen A, Stadler T, Bader M, Siebels M, Karl A, Stief CG

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Recent advances of sorafenib nanoformulations for cancer therapy: Smart nanosystem and combination therapy by Fangmin Chen, Yifan Fang, Xiang Chen, Rui Deng, Yongjie Zhang, Jingwei Shao

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Efficacy and safety of anlotinib combined with the STUPP regimen in patients with newly diagnosed glioblastoma: a multicenter, single-arm, phase II trial by Shuzhen Lai, Peijing Li, Xiaohui Liu, Guihong Liu, Tieming Xie, Xing Zhang, Xiaoxuan Wang, Jing Huang, Yiqiang Tang, Zhigang Liu, Guoping Shen, Chaoming Li, Fangxiao Lu, Lei Wang, Fagui Jiang, Caixing Sun, Yuanyuan Chen, Ming Chen

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Vascular Normalization Caused by Short-Term Lenvatinib Could Enhance Transarterial Chemoembolization in Hepatocellular Carcinoma by Tetsuya Tachiiri, Hideyuki Nishiofuku, Shinsaku Maeda, Takeshi Sato, Shohei Toyoda, Takeshi Matsumoto, Yuto Chanoki, Kiyoyuki Minamiguchi, Ryosuke Taiji, Hideki Kunichika, Satoshi Yamauchi, Takahiro Ito, Nagaaki Marugami, Toshihiro Tanaka

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The Synergistic Cytotoxic Effects of GW5074 and Sorafenib by Impacting Mitochondrial Functions in Human Colorectal Cancer Cell Lines by Je-Ming Hu, Je-Ming Hu, Yung-Lung Chang, Yung-Lung Chang, Cheng-Chih Hsieh, Cheng-Chih Hsieh, Shih-Ming Huang, Shih-Ming Huang

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Design of phase 2 study of TAS-115, a novel oral multi-kinase inhibitor, in patients with idiopathic pulmonary fibrosis by Yasuhiko Nishioka, Sakae Homma, Takahito Okubo, Arata Azuma

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CLINICAL EXPERIENCE OF NEXAVAR (SORAFENIB) APPLICATION IN PATIENTS WITH METASTATIC DIFFERENTIATED THYROID CANCER RESISTANT TO THERAPY 131I by P. A. Isaev, P. O. Rumyantsev, V. V. Polkin, A. A. Ilyin, D. Yu. Syomin, T. A. Agababyan, S. V. Vasilkov, V. S. Medvedev

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Management of Progressive Radioiodine-Refractory Thyroid Carcinoma: Current Perspective by Nervo A, Retta F, Ragni A, Piovesan A, Gallo M, Arvat E

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Emerging Therapies for Childhood Polycystic Kidney Disease by William E. Sweeney, Ellis D. Avner

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Electrolyte disorders induced by six multikinase inhibitors therapy for renal cell carcinoma: a large-scale pharmacovigilance analysis by Xianhua She, Donghong Yin, Qian Guo, Yang Tang, Shuyun Wang, Xuyan Wang

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Efficacy of aluminum chloride in severe regorafenib-associated hand-foot skin reactions: a single-arm trial by Aya Nishizawa, Eiji Shinozaki, Takeru Wakatsuki, Takahiro Satoh, Naoya Yamazaki, Shunsuke Oyamada, Keisuke Ariyoshi, Kota Kihara, Masahiro Tsuboi, Kensei Yamaguchi

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Systemic treatment in patients with Child–Pugh B liver dysfunction and advanced hepatocellular carcinoma by Frederico Costa, Bertram Wiedenmann, Christoph Roderburg, Raphael Mohr, Ghassan K. Abou‐Alfa

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Targeting RET-rearranged non-small-cell lung cancer: future prospects by Bronte G, Ulivi P, Verlicchi A, Cravero P, Delmonte A, Crinò L

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The Efficacy and Safety of the Shouzu Ning Decoction Treatment for Multi-Kinase Inhibitors-Associated Severe Hand–Foot Skin Reaction by Shou L, Shao T, Zhao F, Chen S, Chen Q, Shu Q

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Kinase inhibitor data set for systematic analysis of representative kinases across the human kinome by Oliver Laufkötter, Stefan Laufer, Jürgen Bajorath

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