Evaluating Personalized (N-of-1) Trials in Rare Diseases: How Much Experimentation Is Enough? by Ken Cheung, Hiroshi Mitsumoto

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The Catalyst’s Companion: <i>N</i>,<i>N</i>′-Dicyclohexylcarbodiimide (DCC) in Action by Arshdeep Singh, Anjali Sharma, Pooja A. Chawla

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A framework for N-of-1 trials of individualized gene-targeted therapies for genetic diseases by Olivia Kim-McManus, Joseph G. Gleeson, Laurence Mignon, Amena Smith Fine, Winston Yan, Nicole Nolen, Scott Demarest, Elizabeth Berry-Kravis, Richard Finkel, Stefanie Leonard, Samuel Finlayson, Erika Augustine, Gholson J. Lyon, Rebecca Schule, Timothy Yu

“…By nature these new individualized medicines require testing in individualized N-of-1 trials. Here, we provide a framework for maintaining scientific rigor in N-of-1 trials. …”
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StudyMe: a new mobile app for user-centric N-of-1 trials by Alexander M. Zenner, Erwin Böttinger, Stefan Konigorski

“…Abstract N-of-1 trials are multi-crossover self-experiments that allow individuals to systematically evaluate the effect of interventions on their personal health goals. …”
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Alternative Detection of <em>n</em> = 1 Modes Slowing Down on ASDEX Upgrade by Emmanuele Peluso, Riccardo Rossi, Andrea Murari, Pasqualino Gaudio, Michela Gelfusa, on behalf of the ASDEX Upgrade Team, on behalf of the EUROfusion MST1 Team

“…The estimator is based on a weighted average value of the fast Fourier transform of the perturbed radial <i>n</i> = 1 magnetic field, caused by the rotation of the modes. …”
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The Variational Homotopy Perturbation Method for Solving ((n×n)+1) Dimensional Burgers’ Equations by F. A. Hendi, B. S. Kashkari, A. A. Alderremy

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IN VITRO ANTIPLASMODIAL ACTIVITY AND CYTOTOXICITY OF NEW N-BENZYL 1,10- PHENANTHROLINE DERIVATIVES by , Eti Nurwening Sholikhah, Mahardika Agus Wijayanti, Ruslin Hadanu

“…Based on the skeleton, 3 derivatives of N-benzyl 1,10-phenanthroline: (1)-N-(4-methoxy-benzyl)-1,10-phenanthrolinium bromide (1), (1)-N-(4-ethoxy-benzyl)-1,10-phenanthrolinium chloride (2), and (1)-N-(4-ethoxy-benzyl)-1,10-phenanthrolinium bromide (3) have been synthesized. …”

N-Benzyl-1,3-dide-oxy-1,3-imino-l-xylitol. by Jenkinson, S, Lenagh-Snow, G, Fleet, G, Thompson, A

1-amino-N,N-dibenzyl-1,6-dideoxy-beta-L-fructofuranose by Harding, C, Watkin, D, Hotchkiss, D, Cook, J, Fleet, G

(3-Methylbenzonitrile-1κN)-cis-tetrakis(μ-N-phenylacetamidato)-1:2κ4N:O;1:2κ4O:N-dirhodium(II)(Rh—Rh) by Cassandra T. Eagle, Fredricka Quarshie, Kevin M. Cook

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Synthesis, Characterizatiᴏn, and Bioactivity Assessment of Rh(III) and VO(IV) Complexes with Isatin Derivative <i>N1</i>,<i>N2</i>-bis(2-oxoindolin-3-ylidene)ethanebis(thioamide) by Yusra Jalil Ahmed, Shurooq Abdulfattah Hasan, Waeel Mohammed Hamud, Nawal Hamdan Mahmoud

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In vivo effects of N/OFQ(1–13)NH2 and its structural analogue [ORN9]N/OFQ(1–13)NH2 on carrageenan-induced inflammation: rat-paw oedema and antioxidant status by Zamfirova Rositsa, Tzvetanova Elina, Alexandrova Albena, Petrov Lubomir, Mateeva Polina, Pavlova Almira, Kirkova Margarita, Todorov Simeon

Subjects: “…n/ofq(1–13)nh2…”
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Comment on “Designing Robust N-of-1 Studies for Precision Medicine: Simulation Study and Design Recommendations” by Landes, Reid D

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N-Methyl-4-(4-nitrophenyl)-N-nitroso-1,3-thiazol-2-amine by Anna Jezuita, Grzegorz Spaleniak, Krzysztof Ejsmont, Jacek Zaleski, Bartosz Zarychta

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Scaling Behaviour of <i>dN</i>/<i>dy</i> in High-Energy Collisions by Gábor Kasza, Tamás Csörgő

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A scoping review of randomized trials assessing the impact of n-of-1 trials on clinical outcomes. by Joyce P Samuel, Susan H Wootton, Travis Holder, Donald Molony

“…<h4>Background</h4>The single patient (n-of-1) trial can be used to resolve therapeutic uncertainty for the individual patient. …”
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A Novel N of 1 Trial Design and Proposed Utility in Complementary and Alternative Medicine Research by Joshua Z. Goldenberg BA, Cynthia A. Wenner PhD

“…An N of 1 trial is a multiple crossover study in a single participant. …”
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Synthesis of 1-(methylsulfonyl)-1-propene and N,N-dimethyl-1-propene-1-sulfonamide by Ivan Huzhva, Elena Shvets, Maksim Kolosov

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<i>N</i>-(1-azido-2-(azidomethyl)butan-2-yl)-4-methylbenzenesulfonamide by Sara Hajib, Younas Aouine, Hassane Faraj, Anouar Alami

“…A new bi-triazole precursor, <i>N</i>-(1-azido-2-(azidomethyl)butan-2-yl)-4-methylbenzenesulfonamide, was synthesized in two steps from 2-amino-2-ethyl-1,3-propanediol, with an overall yield of 80%. …”
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A scoping review of randomized trials assessing the impact of n-of-1 trials on clinical outcomes by Joyce P. Samuel, Susan H. Wootton, Travis Holder, Donald Molony

“…<h4>Background</h4> The single patient (n-of-1) trial can be used to resolve therapeutic uncertainty for the individual patient. …”
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