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Effects of fluorescent glutamate indicators on neurotransmitter diffusion and uptake
Published 2020-04-01Get full text
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Genetics of Functional Seizures; A Scoping Systematic Review
Published 2023-07-01Get full text
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Vascular cognitive impairment (VCI): Progress towards knowledge and treatment
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Silver Jubilee of Stroke Thrombolysis With Alteplase: Evolution of the Therapeutic Window
Published 2021-03-01“…In 1995, the results of a landmark clinical trial by National Institute of Neurological Disorders and Stroke (NINDS) made a paradigm shift in managing acute cerebral ischemic stroke (AIS) patients at critical care centers. …”
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Preclinical research in Rett syndrome: setting the foundation for translational success
Published 2012-11-01“…In September of 2011, the National Institute of Neurological Disorders and Stroke (NINDS), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the International Rett Syndrome Foundation (IRSF) and the Rett Syndrome Research Trust (RSRT) convened a workshop involving a broad cross-section of basic scientists, clinicians and representatives from the National Institutes of Health (NIH), the US Food and Drug Administration (FDA), the pharmaceutical industry and private foundations to assess the state of the art in animal studies of Rett syndrome (RTT). …”
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Acute myocardial infarction following intravenous tissue plasminogen activator for acute ischemic stroke: An unknown danger
Published 2010-01-01“…Thrombolysis with intravenous tissue (IV) plasminogen activator (tPA) is considered for patients with acute ischemic stroke falling within the described inclusion criteria defined by The National Institute of Neurological Disorders and Stroke (NINDS) rtPA trial. Complications of IV thrombolysis with tPA are commonly related to hemorrhage, anaphylaxis, or arterial occlusion. …”
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Precompetitive Data Sharing as a Catalyst to Address Unmet Needs in Parkinson’s Disease
Published 2015“…Government agencies included EMA, FDA, NINDS/NIH and IMI (Innovative Medicines Initiative). …”
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Vasküler Kognitif Bozukluk ve Demans, Alzheimer Demans ve Normal Yaşlanma ile İlişkili Beyin Beyaz Cevher Hiperintensite Değişiklikleri
Published 2021-12-01“…The basic clinical criteria of DSM-V and NIA-AA were considered for AD. The DSM-V and NINDS-AIREN diagnostic criteria were used for VCID and probable vascular dementia (VaD). …”
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Stroke recovery phenotyping through network trajectory approaches and graph neural networks
Published 2022-06-01“…To demonstrate the utility of this approach, we analyzed data from the NINDS tPA trial using the Trajectory Profile Clustering (TPC) method to identify distinct stroke recovery patterns for 11 different neurological domains at 5 discrete time points. …”
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Current perspectives on the use of intravenous recombinant tissue plasminogen activator (tPA) for treatment of acute ischemic stroke
Published 2014-02-01“…Sherita N Chapman,1 Prachi Mehndiratta,1 Michelle C Johansen,1 Timothy L McMurry,2 Karen C Johnston,1,2 Andrew M Southerland1,2 1Department of Neurology, University of Virginia, Charlottesville, VA, USA; 2Department of Public Health Sciences, University of Virginia, Charlottesville, VA, USA Abstract: In 1995, the NINDS (National Institute of Neurological Disorders and Stroke) tPA (tissue plasminogen activator) Stroke Study Group published the results of a large multicenter clinical trial demonstrating efficacy of intravenous tPA by revealing a 30% relative risk reduction (absolute risk reduction 11%–15%) compared with placebo at 90 days in the likelihood of having minimal or no disability. …”
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Distribution of AAV-TK following Intracranial Convection-Enhanced Delivery into Rats
Published 2000-09-01Get full text
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A large study reveals no association between APOE and Parkinson's disease
Published 2012-05-01“…Patients and methods: In total, 3465 case and control samples were genotyped, obtained from the NINDS Neurogenetics repository. Results: No significant differences in ε4 dosages exist between PD cases and controls. …”
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