NK cells associate with ALS in a sex- and age-dependent manner by Benjamin J. Murdock, Joshua P. Famie, Caroline E. Piecuch, Kristen D. Raue, Faye E. Mendelson, Cole H. Pieroni, Sebastian D. Iniguez, Lili Zhao, Stephen A. Goutman, Eva L. Feldman

“…NK cells are innate immune cells implicated in ALS; whether NK cells impact ALS in a sex- and age-specific manner was investigated. …”
Get full text

CAR-NK Cells: A Chimeric Hope or a Promising Therapy? by Mohamad Sabbah, Ludovic Jondreville, Claire Lacan, Francoise Norol, Vincent Vieillard, Damien Roos-Weil, Stéphanie Nguyen

“…However, the majority of the reports on CAR-NK cells concern preclinical or early clinical trials. …”
Get full text

Interferon-epsilon is a novel regulator of NK cell responses in the uterus by Jemma R Mayall, Jay C Horvat, Niamh E Mangan, Anne Chevalier, Huw McCarthy, Daniel Hampsey, Chantal Donovan, Alexandra C Brown, Antony Y Matthews, Nicole A de Weerd, Eveline D de Geus, Malcolm R Starkey, Richard Y Kim, Katie Daly, Bridie J Goggins, Simon Keely, Steven Maltby, Rennay Baldwin, Paul S Foster, Michael J Boyle, Pradeep S Tanwar, Nicholas D Huntington, Paul J Hertzog, Philip M Hansbro

“…Regulation of natural killer (NK) cell responses in the uterus during infection is critical, yet no studies have identified uterine-specific factors that control NK cell responses in this immune-privileged site. …”
Get full text

RETRACTED: CAR-NK Cell: A New Paradigm in Tumor Immunotherapy by Faroogh Marofi, Alaa S. Al-Awad, Heshu Sulaiman Rahman, Heshu Sulaiman Rahman, Alexander Markov, Alexander Markov, Walid Kamal Abdelbasset, Walid Kamal Abdelbasset, Yulianna Ivanovna Enina, Mahnaz Mahmoodi, Ali Hassanzadeh, Mahboubeh Yazdanifar, Max Stanley Chartrand, Mostafa Jarahian

“…More importantly, CAR-NK cells represent antigen receptors against tumor-associated antigens (TAAs), thereby redirecting the effector NK cells and supporting tumor-related immunosurveillance. …”
Get full text

The Rise of NK Cell Checkpoints as Promising Therapeutic Targets in Cancer Immunotherapy by Haoyu Sun, Haoyu Sun, Haoyu Sun, Cheng Sun, Cheng Sun, Cheng Sun

Subjects: “…NK cell…”
Get full text

IL-27 imparts immunoregulatory function to human NK cell subsets. by Alice Laroni, Roopali Gandhi, Vanessa Beynon, Howard L Weiner

“…Interleukin-27 (IL-27) is a cytokine with multiple roles in regulating the immune response, but its effect on human CD56(bright) and CD56(dim) NK cell subsets is unknown. NK cell subsets interact with other components of the immune system, leading to cytotoxicity or immunoregulation depending on stimulating factors. …”
Get full text

CAR NK Cell Therapy for the Treatment of Metastatic Melanoma: Potential & Prospects by Winston Hibler, Glenn Merlino, Yanlin Yu

Subjects: Get full text

Antitumor Immunity: Role of NK Cells and Extracellular Vesicles in Cancer Immunotherapy by Angelina E. Prokopeva, Charles C. Emene, Marina O. Gomzikova

“…One promising strategy for treating tumor diseases is NK cell-based immunotherapy. NK cells have the ability to recognize and destroy transformed cells without prior activation as well as tumor cells with reduced MHC-I expression. …”
Get full text

Research Progress of Chimeric Antigen Receptor NK Cells in Treatment of Lymphoma by HU Run, YAO Pei, LI Junen, GUI Renjie, DUAN Huaxin

“…This review will systematically introduce the current research status of CAR-NK cells in lymphoma.…”
Get full text

CAR-NK cells for cancer immunotherapy: recent advances and future directions by Tianye Li, Tianye Li, Mengke Niu, Weijiang Zhang, Weijiang Zhang, Shuang Qin, Jianwei Zhou, Jianwei Zhou, Ming Yi

“…Unlike predominant treatments that target T cell immunity, the limited success of T cell immunotherapy emphasizes the urgency for innovative approaches, with a spotlight on harnessing the potential of NK cells. Despite tumors adapting mechanisms to evade NK cell-induced cytotoxicity, there is optimism surrounding Chimeric Antigen Receptor (CAR) NK cells. …”
Get full text

T and NK Cell-Based Immunotherapy in Chronic Viral Hepatitis and Hepatocellular Carcinoma by Paola Fisicaro, Carolina Boni

“…In chronic viral hepatitis and in hepatocarcinoma (HCC), antigen-specific T cells are deeply exhausted, and evidence of dysfunction has also been observed for NK cells, which can play a pathogenetic role, exerting a regulatory activity on adaptive immune responses [...]…”
Get full text

Rough operators: sphingomyelinase inhibitors spike NK cells to kill cancer by Mattias Carlsten, Yenan T. Bryceson

Get full text

NK cells propagate T cell immunity following in situ tumor vaccination by Won Jong Jin, Justin C. Jagodinsky, Jessica M. Vera, Paul A. Clark, Cindy L. Zuleger, Amy K. Erbe, Irene M. Ong, Trang Le, Kaitlin Tetreault, Tracy Berg, Alexander L. Rakhmilevich, KyungMann Kim, Michael A. Newton, Mark R. Albertini, Paul M. Sondel, Zachary S. Morris

“…This is dependent on NK cell expression of CD86, which is upregulated downstream of KLRK1. …”
Get full text

Immunological Drivers in Graves' Disease: NK Cells as a Master Switcher by Daniela Gallo, Eliana Piantanida, Matteo Gallazzi, Luigi Bartalena, Maria Laura Tanda, Antonino Bruno, Lorenzo Mortara

“…We analyzed cellular and molecular NK-cell associated mechanisms potentially impacting on GD, in a view of identification of the main NK-cell subset with highest immunoregulatory role.…”
Get full text

Licensed and unlicensed NK cells: Differential roles in cancer and viral control by Megan M Tu, Ahmad Bakur Mahmoud, Ahmad Bakur Mahmoud, Andrew P Makrigiannis

Subjects: Get full text

Phenotypic diversity of human adipose tissue-resident NK cells in obesity by Martha E. Haugstøyl, Martha E. Haugstøyl, Martin Cornillet, Kristina Strand, Kristina Strand, Natalie Stiglund, Dan Sun, Laurence Lawrence-Archer, Laurence Lawrence-Archer, Iren D. Hjellestad, Iren D. Hjellestad, Christian Busch, Gunnar Mellgren, Gunnar Mellgren, Niklas K. Björkström, Johan Fernø, Johan Fernø

Subjects: Get full text

Microchip screening platform for single cell assessment of NK cell cytotoxicity by Karolin eGuldevall, Ludwig eBrandt, Elin eForslund, Elin eForslund, Karl eOlofsson, Thomas Wilhelm Frisk, Per Erik Olofsson, Karin eGustafsson, Bruno eVanherberghen, Otto eManneberg, Hjalmar eBrismar, Klas eKärre, Michael eUhlin, Michael eUhlin, Björn eÖnfelt, Björn eÖnfelt

Subjects: Get full text

Non-Genetically Improving the Natural Cytotoxicity of Natural Killer (NK) Cells by Martin Villalba, Martin Villalba, Catherine Alexia, Anais Bellin-Robert, Alexis Fayd'herbe de Maudave, Delphine Gitenay

Subjects: “…NK cells…”
Get full text

Killing the Invaders: NK Cell Impact in Tumors and Anti-Tumor Therapy by Martina Molgora, Victor S. Cortez, Marco Colonna

Subjects: “…NK cells…”
Get full text

Revisiting the prominent anti-tumoural potential of pre-mNK cells by Fanny eGuimont-Desrochers, Sylvie eLesage

Subjects: Get full text