Implications of a ‘Third Signal’ in NK Cells by Mohamed Khalil, Dandan Wang, Elaheh Hashemi, Scott S. Terhune, Subramaniam Malarkannan

Subjects: “…NK cells…”
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NK cell education: Physiological and pathological influences by Philippe Rascle, Philippe Rascle, Griffin Woolley, Griffin Woolley, Stephanie Jost, Stephanie Jost, Cordelia Manickam, Cordelia Manickam, R. Keith Reeves, R. Keith Reeves, R. Keith Reeves

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NK Cells in Protection from HIV Infection by Nicole F. Bernard, Khlood Alsulami, Erik Pavey, Franck P. Dupuy

“…NK cells can interact with both autologous HIV-infected cells and allogeneic cells bearing MHC antigens seen as non self by educated NK cells. …”
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Editorial: NK cells in viral immunology and immunotherapy by Sachin Mulik, Pranay Dogra, Nabila Jabrane-Ferrat

Subjects: “…NK cells…”
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The Role of NK Cells in Pig-to-Human Xenotransplantation by Gisella Puga Yung, Mårten K. J. Schneider, Jörg D. Seebach

“…Recruitment of human NK cells to porcine tissues has been demonstrated in pig organs perfused ex vivo with human blood in the early 1990s. …”
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NK cells support osteoclast formation in vitro by Owen, S, Danks, L, Sarma, U, Feldmann, M, Brennan, R, Horwood, N

Imaging immune surveillance by T cells and NK cells. by McCann, F, Suhling, K, Carlin, L, Eleme, K, Taner, S, Yanagi, K, Vanherberghen, B, French, P, Davis, D

“…As T cells and natural killer (NK) cells survey the surface of other cells, cognate receptors and ligands are commonly organized into distinct micrometer-scale domains at the intercellular contact, creating an immune or immunological synapse (IS). …”

NK cells support osteoclast formation in vitro by Danks, L, Owen, S, Feldmann, M, Brennan, F, Horwood, N

Functional dichotomy of NK cells in organ transplantation. by Tha-In, T, Luo, S, Bushell, A, Wood, K

“…Evaluation of: Yu G, Xu X, Vu MD, Kilpatrick ED, Li XC. NK cells promote transplant tolerance by killing donor antigen-presenting cells. …”

NK cells and human pregnancy--an inflammatory view. by Sargent, I, Borzychowski, A, Redman, C

“…The discovery that normal pregnancy is a controlled state of inflammation, at an early stage at the implantation site and also later systemically, has challenged this concept, as has the finding that the predominant immune interactions in the decidua are between the placental trophoblast and maternal natural killer (NK) cells instead of T cells. Here, we extend this concept to the interaction between the trophoblast and NK cells in the maternal circulation. …”

329 Redirecting NK cell cytotoxicity by innate cell engagers: a differentiated and innovative approach compared to CAR-NK cells by Ivica Fucek, Joachim Koch, Thomas Grunwald, Jens Pahl, Christian Breunig, Sonya Ioana Ciulean, Julia Uhlig, Thea Eichenberg, Joe Fischer, Michael Albers, Jan Schmollinger, Christoph Bach, Paul Franz, Anna Dünkel, Stephan Fricke, Ulrike Köhl

PECULIARITIES OF NK CELLS DIFFERENTIATION: CD56dim AND CD56bright NK CELLS AT PREGNANCY AND IN NON-PREGNANT STATE by V. A. Mikhailova, K. L. Belyakova, S. A. Selkov, D. I. Sokolov

Subjects: “…nk cells…”
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The co-inhibitory receptor TIGIT regulates NK cell function and is upregulated in human intrahepatic CD56bright NK cells by Annerose E. Ziegler, Annerose E. Ziegler, Pia Fittje, Luisa M. Müller, Annika E. Ahrenstorf, Kerri Hagemann, Sven H. Hagen, Leonard U. Hess, Annika Niehrs, Tobias Poch, Gevitha Ravichandran, Sebastian M. Löbl, Benedetta Padoan, Sébastien Brias, Sébastien Brias, Jana Hennesen, Myrtille Richard, Laura Richert, Sven Peine, Karl J. Oldhafer, Lutz Fischer, Christoph Schramm, Christoph Schramm, Glòria Martrus, Madeleine J. Bunders, Madeleine J. Bunders, Marcus Altfeld, Sebastian Lunemann

Subjects: “…intrahepatic NK cells…”
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NK Cells Equipped With a Chimeric Antigen Receptor That Overcomes Inhibition by HLA Class I for Adoptive Transfer of CAR-NK Cells by Xiaoxuan Zhuang, Eric O. Long

“…Dominant inhibitory receptors for HLA class I (HLA-I) endow NK cells with high intrinsic responsiveness, a process termed licensing or education, but hinder their ability to kill HLA-I+ tumor cells. …”
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g-NK cells from umbilical cord blood are phenotypically and functionally different than g-NK cells from peripheral blood by Fei Gao, Mauricio Campos Mora, Michael Constantinides, Loïs Coenon, Caroline Multrier, Loïc Vaillant, Tianxiang Zhang, Martin Villalba

“…FcRγ-deficient natural killer (NK) cells, designated as g-NK cells, exhibit enhanced antibody-dependent cellular cytotoxicity (ADCC) capacity and increased IFN-γ and TNF-α production, rendering them promising for antiviral and antitumor responses. g-NK cells from peripheral blood (PB) are often associated with prior human cytomegalovirus (HCMV) infection. …”
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Suppressive effects of obesity on NK cells: is it time to incorporate obesity as a clinical variable for NK cell-based cancer immunotherapy regimens? by William J Murphy, Robert J Canter, Sean J Judge, Craig P Collins, Daniel Jaeho Yoon

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Improvement of NK Cell Cytotoxicity in Reconstituting NK Cells after Allogeneic Stem Cell Transplantation by Blocking NKG2A Checkpoint by Mohammed Taha, Cyril Fauriat

“…Background: One cause of tumor relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the alteration of the graft-versus-tumor effect of early reconstituting natural killer (NK) cells due to overexpression of the NKG2A inhibitory receptor. …”
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Advances in bioengineered CAR T/NK cell therapy for glioblastoma: Overcoming immunosuppression and nanotechnology‐based strategies for enhanced CAR T/NK cell therapy by Nasim Dana, Arezou Dabiri, Majed Bahri Najafi, Azadeh Rahimi, Sayed Mohammad Matin Ishaghi, Laleh Shariati, Minmin Shao, Assunta Borzacchiello, Ilnaz Rahimmanesh, Pooyan Makvandi

“…In addition, this review presents valuable insights into the integration of nanotechnology into CAR T/NK cell therapy for enhanced efficiency of these personalized gene therapy products.…”
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NK cell-derived exosomes enhance the anti-tumor effects against ovarian cancer by delivering cisplatin and reactivating NK cell functions by Heyong Luo, Heyong Luo, Yanhua Zhou, Jing Zhang, Yingchun Zhang, Shiqi Long, Xiaojin Lin, Xiaojin Lin, Anqing Yang, Anqing Yang, Jiangyao Duan, Na Yang, Na Yang, Zhiru Yang, Zhiru Yang, Qiyuan Che, Qiyuan Che, Yuxin Yang, Yuxin Yang, Ting Guo, Dan Zi, Weiwei Ouyang, Wei Yang, Zhu Zeng, Xing Zhao, Xing Zhao

“…We demonstrate that eNK-EXO express typical protein markers of natural killer (NK) cells, can be preferentially uptaken by SKOV3 cells, and display cytotoxicity against OC cells. …”
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Expression of a variant of CD28 on a subpopulation of human NK cells: implications for B7-mediated stimulation of NK cells. by Galea-Lauri, J, Darling, D, Gan, S, Krivochtchapov, L, Kuiper, M, Gäken, J, Souberbielle, B, Farzaneh, F

“…The ability of NK cells to kill tumor cells is controlled by a balance between activating and inhibitory signals transduced by distinct receptors. …”