Exhausted signature and regulatory network of NK cells in myasthenia gravis by Qing Zhang, Qing Zhang, Xingyu Han, Xingyu Han, Zhuajin Bi, Zhuajin Bi, Mengge Yang, Mengge Yang, Jing Lin, Jing Lin, Zhijun Li, Zhijun Li, Min Zhang, Min Zhang, Bitao Bu, Bitao Bu

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The application of autologous cancer immunotherapies in the age of memory-NK cells by Gaby D. Lizana-Vasquez, Gaby D. Lizana-Vasquez, Madeline Torres-Lugo, R. Brent Dixon, R. Brent Dixon, John D. Powderly, John D. Powderly, Renaud F. Warin, Renaud F. Warin

“…Cellular immunotherapy has revolutionized the oncology field, yielding improved results against hematological and solid malignancies. NK cells have become an attractive alternative due to their capacity to activate upon recognition of “stress” or “danger” signals independently of Major Histocompatibility Complex (MHC) engagement, thus making tumor cells a perfect target for NK cell-mediated cancer immunotherapy even as an allogeneic solution. …”
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NK Cells in the Lymph Nodes and Their Role in Anti-Tumour Immunity by Lara V. Graham, Salim I. Khakoo, Matthew D. Blunt

Subjects: “…natural killer (NK) cells…”
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The role of CD56bright NK cells in neurodegenerative disorders by Carla Rodriguez-Mogeda, Chaja M. J. van Ansenwoude, Lennart van der Molen, Eva M. M. Strijbis, Reina E. Mebius, Helga E. de Vries

Subjects: “…CD56bright NK cells…”
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Analysis of the impact of handling and culture on the expansion and functionality of NK cells by Sara Martin-Iglesias, Lara Herrera, Lara Herrera, Silvia Santos, Silvia Santos, Silvia Santos, Miguel Ángel Vesga, Miguel Ángel Vesga, Miguel Ángel Vesga, Cristina Eguizabal, Cristina Eguizabal, Cristina Eguizabal, Cristina Eguizabal, Senentxu Lanceros-Mendez, Senentxu Lanceros-Mendez, Senentxu Lanceros-Mendez, Unai Silvan, Unai Silvan, Unai Silvan

“…Natural killer (NK) cells are lymphocytes of the innate immune system that play a key role in the elimination of tumor and virus-infected cells. …”
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Differential impact of TIM-3 ligands on NK cell function by Xin Zhang, Lazar Vujanovic, Riyue Bao, Robert L Ferris, Tullia C Bruno, Aditi Kulkarni, Hridesh Banerjee, Housaiyin Li, Juncheng Wang, Lawrence P Kane, Pragati Upadhyay, Jennifer L Anderson, Onyedikachi Victor Onyekachi, Lidia M R B Arantes

“…The primary objectives of this study were to assess the prevalence and function of TIM-3+ natural killer (NK) cells in patients with head and neck squamous cell carcinoma (HNSCC), determine whether the four TIM-3 ligands differentially affect TIM-3+ NK cell functions, identify the most immunosuppressive ligand, and evaluate whether targeting ligand-mediated TIM-3 signaling enhances NK cell effector functions.Methods Single-cell RNA sequencing and flow cytometry were used to study the prevalence, phenotypes and function of TIM-3+ NK cells in HNSCC patient tumors and blood. …”
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NK Cell Patterns in Idiopathic Inflammatory Myopathies with Pulmonary Affection by Marc Pawlitzki, Christopher Nelke, Leoni Rolfes, Rebecca Hasseli, Stylianos Tomaras, Eugen Feist, Anne Schänzer, Saskia Räuber, Liesa Regner, Corinna Preuße, Yves Allenbach, Olivier Benveniste, Heinz Wiendl, Werner Stenzel, Sven G. Meuth, Tobias Ruck

“…NK cell alterations were driven by a particular decrease of CD56^dim NK cells, while CD56^bright NK cells remained unchanged. …”
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Cytotoxic Responses Mediated by NK Cells and Cytotoxic T Lymphocytes in Xenotransplantation by Viktoriia Galdina, Gisella L. Puga Yung, Jörg D. Seebach

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Preclinical and clinical studies of CAR-NK-cell therapies for malignancies by Hongwen Li, Hongwen Li, Hongwen Li, Wenting Song, Wenting Song, Wenting Song, Wenting Song, Zhaoming Li, Zhaoming Li, Zhaoming Li, Mingzhi Zhang, Mingzhi Zhang, Mingzhi Zhang

“…In this review, we will address the advances in and achievements of CAR-NK cell therapy.…”
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Phenotype of Peripheral NK Cells in Latent, Active, and Meningeal Tuberculosis by José Alberto Choreño-Parra, Luis Armando Jiménez-Álvarez, Ellis Daniela Maldonado-Díaz, Graciela Cárdenas, Luis Alejandro Fernández-Lopez, José Luis Soto-Hernandez, Marcela Muñoz-Torrico, Gustavo Ramírez-Martínez, Alfredo Cruz-Lagunas, Armando Vega-López, María Lilia Domínguez-López, Carlos Sánchez-Garibay, Parménides Guadarrama-Ortíz, Silvia Giono, Luis Antonio Jiménez-Zamudio, Shabaana A. Khader, Ethel A. García-Latorre, Citlaltepetl Salinas-Lara, Joaquín Zúñiga

“…Also, we addressed the responses of memory-like NK cell subpopulations to the contact with Mtb antigens in vitro. …”
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Exercise: a non-drug strategy of NK cell activation by Huixin Pan, Rui Meng, Zixuan Jia, Jing Zhang, Wen Ma, Youhan Liu, Qinglu Wang, Qiaoqiao Li

Subjects: “…NK cell…”
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Differential Regulation of NK Cell Receptors in Acute Lymphoblastic Leukemia by Le Jie Lee, Norfarazieda Hassan, Siti Zuleha Idris, Suresh Kumar Subbiah, Heng Fong Seow, Norhafizah Mohtaruddin, Kian Meng Chang, Raudhawati Osman, Hishamshah Mohd Ibrahim, Sheila Nathan, Maha Abdullah

“…Thus, ALL subtypes potentially regulated NK cell suppression by different mechanisms which should be considered in future immunotherapies for ALL.…”
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Balancing act: the complex role of NK cells in immune regulation by Hongwei Jiang, Hongwei Jiang, Hongwei Jiang, Jingting Jiang, Jingting Jiang, Jingting Jiang

Subjects: “…NK cell…”
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An ELF4 hypomorphic variant results in NK cell deficiency by Sandra Andrea Salinas, Emily M. Mace, Matilde I. Conte, Chun Shik Park, Yu Li, Joshua I. Rosario-Sepulveda, Sanjana Mahapatra, Emily K. Moore, Evelyn R. Hernandez, Ivan K. Chinn, Abigail E. Reed, Barclay J. Lee, Alexander Frumovitz, Richard A. Gibbs, Jennifer E. Posey, Lisa R. Forbes Satter, Akaluck Thatayatikom, Eric J. Allenspach, Theodore G. Wensel, James R. Lupski, H. Daniel Lacorazza, Jordan S. Orange

“…NK cell deficiencies (NKD) are a type of primary immune deficiency in which the major immunologic abnormality affects NK cell number, maturity, or function. …”
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Opinion Article: NK Cells in Cutaneous Leishmaniasis: Protection or Damage? by Marton Kaique de Andrade Cavalcante, Marton Kaique de Andrade Cavalcante, Rafael de Freitas e Silva, Rafael de Freitas e Silva, Valéria Rêgo Alves Pereira, Maria Carolina Accioly Brelaz-de-Castro, Maria Carolina Accioly Brelaz-de-Castro

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Increased PD-1+ NK Cell Subset in the Older Population by Deng M, Zeng Y, Liu Y, Wang X, Chen N, Zhang M, Jiang M, Zhao H, Du J

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CAR-NK cells: A promising cellular immunotherapy for cancer by Xie, Guozhu, Dong, Han, Liang, Yong, Ham, James Dongjoo, Rizwan, Romee, Chen, Jianzhu

“…© 2020 The Author(s) Natural Killer (NK) cells and CD8+ cytotoxic T cells are two types of immune cells that can kill target cells through similar cytotoxic mechanisms. …”
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CAR-NK cells: A promising cellular immunotherapy for cancer by Xie, Guozhu, Dong, Han, Liang, Yong, Ham, James Dongjoo, Rizwan, Romee, Chen, Jianzhu

“…© 2020 The Author(s) Natural Killer (NK) cells and CD8+ cytotoxic T cells are two types of immune cells that can kill target cells through similar cytotoxic mechanisms. …”
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N-cadherin protects oral cancer cells from NK cell killing in the circulation by inducing NK cell functional exhaustion via the KLRG1 receptor by Qin Xu, Chao Lou, Kailiu Wu, Jianbo Shi, Zhenlin Dai

“…Soluble N-cadherin triggered NK cell functional exhaustion by interacting with the killer cell lectin-like receptor subfamily G member 1 (KLRG1) receptor and therefore protected tumor cells from NK cell killing in the circulation. …”
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Parainfluenza Virus 5 V Protein Blocks Interferon Gamma-Mediated Upregulation of NK Cell Inhibitory Ligands and Improves NK Cell Killing of Neuroblastoma Cells by Elisabeth M. Shiffer, Jeremiah L. Oyer, Alicja J. Copik, Griffith D. Parks

“…NK cell inhibitory ligands can be upregulated on tumor cell surfaces in response to interferon-gamma (IFN-γ), a cytokine which is produced by activated NK cells. …”
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