Surface enhanced Raman spectroscopy on a flat graphene surface by Xu, Weigao, Ling, Xi, Xiao, Jiaqi, Dresselhaus, Mildred, Kong, Jing, Hu, Hongxing, Liu, Zhongfan, Zhang, Jin

“…During the past decades, researchers have made great efforts towards an ideal SERS substrate, mainly including pioneering works on the preparation of uniform metal nanostructure arrays by various nanoassembly and nanotailoring methods, which give better uniformity and reproducibility. …”
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Stimuli-Responsive Boron-Based Materials in Drug Delivery by Bhaskar C. Das, Parthiban Chokkalingam, Pavithra Masilamani, Srushti Shukla, Sasmita Das

“…The potential of developing their capabilities to a wide range of nanoscale systems, such as nanoparticles, nanosheets/nanospheres, nanotubes, nanocarriers, microneedles, nanocapsules, hydrogel, nanoassembly, etc., is also addressed and examined. This review also provides overall design principles to include stimuli-responsive boron nanomaterial-based drug delivery systems, which might inspire new concepts and applications.…”
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Improving the Cellular Uptake of Biomimetic Magnetic Nanoparticles by Federica Vurro, Ylenia Jabalera, Silvia Mannucci, Giulia Glorani, Alberto Sola-Leyva, Marco Gerosa, Alessandro Romeo, Maria Grazia Romanelli, Manuela Malatesta, Laura Calderan, Guillermo R. Iglesias, María P. Carrasco-Jiménez, Concepcion Jimenez-Lopez, Massimiliano Perduca

“…Based on that, difficulties shown in previous studies related to poor cell uptake of BMNPs can be overcome by the novel nanoassembly described here.…”
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Iron oxide@chlorophyll clustered nanoparticles eliminate bladder cancer by photodynamic immunotherapy-initiated ferroptosis and immunostimulation by Yu-Cheng Chin, Li-Xing Yang, Fei-Ting Hsu, Che-Wei Hsu, Te-Wei Chang, Hsi-Ying Chen, Linda Yen-Chien Chen, Zi Chun Chia, Chun-Hua Hung, Wu-Chou Su, Yi-Chun Chiu, Chih-Chia Huang, Mei-Yi Liao

“…Herein, we developed a facile one-pot coprecipitation reaction to fabricate cluster-structured nanoparticles (CNPs) assembled from Fe3O4 and iron chlorophyll (Chl/Fe) photosensitizers. This nanoassembled CNP, as a multifunctional theranostic agent, could perform red-NIR fluorescence and change the redox balance by the photoinduction of reactive oxygen species (ROS) and attenuate iron-mediated lipid peroxidation by the induction of a Fenton-like reaction. …”
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Amphiphilic Cyclodextrin Nanoparticles as Delivery System for Idebenone: A Preformulation Study by Federica De Gaetano, Angela Scala, Consuelo Celesti, Kim Lambertsen Larsen, Fabio Genovese, Corrado Bongiorno, Loredana Leggio, Nunzio Iraci, Nunzio Iraci, Antonino Mazzaglia, Cinzia Anna Ventura

“…Octanoyl-β-cyclodextrin is an amphiphilic cyclodextrin (ACyD8) bearing, on average, ten octanoyl substituents able to self-assemble in aqueous solutions, forming various typologies of supramolecular nanoassemblies. Here, we developed nanoparticles based on ACyD8 (ACyD8-NPs) for the potential intranasal administration of IDE to treat neurological disorders, such as Alzheimer’s Disease. …”
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Development of MRI-Detectable Boron-Containing Gold Nanoparticle-Encapsulated Biodegradable Polymeric Matrix for Boron Neutron Capture Therapy (BNCT) by Chun-Yi Wu, Hsin-Hua Hsieh, Ting-Yu Chang, Jia-Jia Lin, Chin-Ching Wu, Ming-Hua Hsu, Ming-Chia Lin, Shin-Lei Peng

“…This study aimed to develop a novel magnetic resonance imaging (MRI)-detectable boron (B)-containing nanoassemblies and evaluate their potential for boron neutron capture therapy (BNCT). …”
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Engineering of Amphiphilic Erlotinib Analogue as Novel Nanomedicine for Non-Small Cell Lung Cancer Therapy by Cong M, Pang H, Xie G, Li F, Li C, Sun H, Yang S, Zhao W

“…To enhance the efficacy of targeted agents, we demonstrate a novel self-assemble amphiphilic molecule based on erlotinib as an effective nanodrug for anti-cancer treatment.Methods: An amphiphilic molecule composed of hydrophobic erlotinib and hydrophilic biotin block was synthesized and characterized by nuclear magnetic resonance (NMR) as well as high-resolution mass spectrometry (HRMS). Then, nanoassemblies of the amphiphilic molecules are formulated by using nanoprecipitation method. …”
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Three-Biomarker Joint Strategy for Early and Accurate Diagnosis of Acute Myocardial Infarction via a Multiplex Electrochemiluminescence Immunoarray Coupled with Robust Machine Lear... by Mingquan Guo, Dexin Du, Jue Wang, Yao Ma, Di Yang, Mohammad A. Haghighatbin, Jiangnan Shu, Wei Nie, Ruoxian Zhang, Zhiping Bian, Liansheng Wang, Zachary J. Smith, Hua Cui

“…The ECL immunoarray is based on an array microchip with a single-electrode and chemiluminescent immuno-Gold (ciGold) nanoassemblies. The ciGold immunoarray was obtained by successively assembling nanocomposites of Cu2+/cysteine complexes and N-(aminobutyl)-N-(ethylisoluminol) bifunctionalized gold nanoparticles combined with chitosan and antibody conjugated gold nanoparticles on the surface of a microchip. …”
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A Self-Assembling Amphiphilic Peptide Dendrimer-Based Drug Delivery System for Cancer Therapy by Dandan Zhu, Huanle Zhang, Yuanzheng Huang, Baoping Lian, Chi Ma, Lili Han, Yu Chen, Shengmei Wu, Ning Li, Wenjie Zhang, Xiaoxuan Liu

“…These AmPDs assembled into nanoassemblies for efficient encapsulation of the anti-cancer drug doxorubicin (DOX). …”
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Effective use of dry foaming agents in the manufacture of foam gypsum thermal insulation nanocompositions by Ruslan I. Shigapov, Dmitry A. Sinitsin, Rauf M. Khalikov, Elena A. Solovyeva, Igor V. Nedoseko

“…Controlled hardening of gypsum foam nanoassemblers using dry foaming agents is a promising direction in the technology of production of heat-insulating building materials. …”
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Bioengineered Carboxymethylcellulose–Peptide Hybrid Nanozyme Cascade for Targeted Intracellular Biocatalytic–Magnetothermal Therapy of Brain Cancer Cells by Alexandra A. P. Mansur, Sandhra M. Carvalho, Luiz Carlos A. Oliveira, Elaine Maria Souza-Fagundes, Zelia I. P. Lobato, Maria F. Leite, Herman S. Mansur

“…They formed inorganic–inorganic dual-nanozyme systems functionalized by a carboxymethylcellulose biopolymer organic shell, which can trigger a biocatalytic cascade reaction in the cancer tumor microenvironment for the combination of magnetothermal–chemodynamic therapy. These nanoassemblies were produced through a <i>green</i> aqueous process under mild conditions and chemically biofunctionalized with integrin-targeting peptide (iRDG), creating bioengineered nanocarriers. …”
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